DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Vps26 and Vps26a

DIOPT Version :9

Sequence 1:	NP_569952.2	Gene:	Vps26 / 31144	FlyBaseID:	FBgn0014411	Length:	478	Species:	Drosophila melanogaster
Sequence 2:	XP_006256522.1	Gene:	Vps26a / 361846	RGDID:	1359254	Length:	359	Species:	Rattus norvegicus

Alignment Length:	311	Identity:	213/311 - (68%)
Similarity:	252/311 - (81%)	Gaps:	4/311 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 NFLG--FGQSADIEIVF-DGAEHKTAEVKGEDGKVEKMLLFYDGETVSGKVNVTLKKPGSKLEHQ 63
            :|||  ||...:|::.. ||...|.||:|.|||||||..||||||:||||||:..|:||.:||||
  Rat    34 SFLGGFFGPICEIDVALSDGETRKMAEMKTEDGKVEKHYLFYDGESVSGKVNLAFKQPGKRLEHQ 98

  Fly    64 GIKIEFIGQIELYYDRGNHHEFKCLAKALARPGDLIQNNSYPFDFPKVEKQFEVYAGSNVRLRYF 128
            ||:|||:|||||:.|:.|.|||..|.|.||.||:|.|:.||.|:|.:|||.:|.|.|:|||||||
  Rat    99 GIRIEFVGQIELFNDKSNTHEFVNLVKELALPGELTQSRSYDFEFMQVEKPYESYIGANVRLRYF 163

  Fly   129 LRATIVRRISDITKEVDIAVHTLCSYPEMNNPIKMEVGIEDCLHIEFEYNKSKYHLRDTIIGKIY 193
            |:.|||||::|:.||.|:.||.|.:|||:||.||||||||||||||||||||||||:|.|:||||
  Rat   164 LKVTIVRRLTDLVKEYDLIVHQLATYPEVNNSIKMEVGIEDCLHIEFEYNKSKYHLKDVIVGKIY 228

  Fly   194 FLLVRIKIKHMEIAIIKKESTGTGPTMFNENETIAKYEIMDGAPVKGESIPIRVFLAGYNLTPTM 258
            ||||||||:|||:.:||||.||.||:...|.||||||||||||||||||||||:|||||:.||||
  Rat   229 FLLVRIKIQHMELQLIKKEITGIGPSTTTETETIAKYEIMDGAPVKGESIPIRLFLAGYDPTPTM 293

  Fly   259 RDINKKFSVKYFLNLVLMDTEDRRYFKQQEITLWRKA-DKPRYHGAQQHQQ 308
            ||:||||||:|||||||:|.|||||||||||.||||| :|.|......||:
  Rat   294 RDVNKKFSVRYFLNLVLVDEEDRRYFKQQEIILWRKAPEKLRKQRTNFHQR 344

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Vps26	NP_569952.2	Vps26	6..280	CDD:146336	190/274 (69%)
Vps26a	XP_006256522.1	Vps26	40..315	CDD:146336	190/274 (69%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	419	1.000	Domainoid score	I622
eggNOG	1	0.900	-	-		E1_KOG3063
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53681
OrthoDB	1	1.010	-	-		D342422at33208
OrthoFinder	1	1.000	-	-		FOG0001850
OrthoInspector	1	1.000	-	-		otm45458
orthoMCL	1	0.900	-	-		OOG6_101403
Panther	1	1.100	-	-	O	PTHR12233
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1209
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	12	11.830