DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Pgam5 and pgam-5

DIOPT Version :9

Sequence 1:	NP_569951.1	Gene:	Pgam5 / 31143	FlyBaseID:	FBgn0023517	Length:	289	Species:	Drosophila melanogaster
Sequence 2:	NP_495593.2	Gene:	pgam-5 / 174231	WormBaseID:	WBGene00019941	Length:	284	Species:	Caenorhabditis elegans

Alignment Length:	254	Identity:	111/254 - (43%)
Similarity:	156/254 - (61%)	Gaps:	13/254 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 RDPQTVVQNSWTHSDKPVD---PWALWDTNWDCREPRALVRPLRNSQPEEENRYNAELEKAKAKK 85
            |......||   |..|..|   |...||.|||.|:|.:||...:..:.:||.:... :|:.||..
Worm    33 RTASAFTQN---HGHKTFDEHFPRGEWDKNWDFRDPISLVDKGKWEKADEEGKKKL-IEEKKATA 93

  Fly    86 ARHIILVRHGEY-LDVGDSDDTHHLTERGRKQAEFTGKRLCELGIKWDKVVASTMVRAQETSDII 149
            .|:|.|:|||:| ||    .:...||..||:|||..||||....||:..:..||||||.||::||
Worm    94 TRNIFLIRHGQYHLD----HEVKMLTPLGREQAELLGKRLANSDIKFTNMTMSTMVRATETANII 154

  Fly   150 LKQIDFEKEKVVNCAFLREGAPIPPQPPVGHWKPEASQFLRDGSRIEAGFRRYFHRAYPDQEKES 214
            ||.:..:..: .:..|:.||.|.||.|....|:|...:|..:.:|||:.:|:.||||.|.|:::|
Worm   155 LKHLPDDLTR-TSSPFIEEGPPYPPVPDHKTWRPLDPEFYTEAARIESAYRKIFHRASPSQKEDS 218

  Fly   215 YTLIVGHGNVIRYFVCRALQFPAEGWLRININHASITWLTISPSGNVSIKYLGDSGFMP 273
            :.|||.|.||||||:|||||||.|||||:::.:.|:||:||.|.|:||::.:||.|.:|
Worm   219 FELIVCHANVIRYFICRALQFPPEGWLRMSLGNCSLTWITIRPKGHVSVRSIGDIGHLP 277

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pgam5	NP_569951.1	HP_PGM_like	88..265	CDD:132718	85/177 (48%)
pgam-5	NP_495593.2	HP_PGM_like	96..270	CDD:132718	85/178 (48%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160157802
Domainoid	1	1.000	79	1.000	Domainoid score	I5660
eggNOG	1	0.900	-	-		E1_KOG4609
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H14597
Inparanoid	1	1.050	206	1.000	Inparanoid score	I2426
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG58579
OrthoDB	1	1.010	-	-		D1112626at2759
OrthoFinder	1	1.000	-	-		FOG0006616
OrthoInspector	1	1.000	-	-		otm14764
orthoMCL	1	0.900	-	-		OOG6_104882
Panther	1	1.100	-	-	LDO	PTHR20935
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2720
SonicParanoid	1	1.000	-	-		X4856
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	16	15.840