Protein Alignment Pex5 and Pex5l

DIOPT Version :10

• Sequence 1: NP_726771.1
• Gene: Pex5 / 31141
• FlyBaseID: FBgn0023516
• Length: 614
• Species: Drosophila melanogaster
• Sequence 2: XP_063137479.1
• Gene: Pex5l / 286937
• RGDID: 708407
• Length: 673
• Species: Rattus norvegicus
• Alignment Length: 619
• Identity: 192/619 - (31%)
• Similarity: 302/619 - (48%)
• Gaps: 117/619 - (18%)

  Fly    30 LCNT----VTKPIASITA-------------------DKQLRSISTSNTMSFRPLVEGDCGGVNP 71
            ||.|    :.||:.|.||                   .|..:|.|:|.:.|.:...:|.
  Rat   132 LCETKSEAIAKPVTSNTAVLTTGLDLLDLSEPVSQTQTKAKKSESSSKSSSLKKKADGS------ 190

  Fly    72 LMQLGGQFTRDVAHKDEGYVQRHFERAARPEDQLINEFLGQVTAPPQSFQMDTLLQEMRDINIHG 136
                      |:...|              .:|......|..|:......:.|.|::..|:..||
  Rat   191 ----------DLISAD--------------AEQRAQALRGPETSSLDLVDIQTQLEKWDDVKFHG 231

  Fly   137 NPQQQMHSQQAEQWGQDFARGLAPALPNKMIHMQAQQQDLQHAQEFFDEPLI----SSQNFRSLP 197
            :...:.| ..||:               |....:|..::|..:.|...:|.:    |:.|..|..
  Rat   232 DRTSKGH-LMAER---------------KSCSSRAGSKELLWSSEHRSQPELSTGKSALNSESAS 280

  Fly   198 PLRQPLMPIAAGQQQDPFFDSAMETIITDHLPQAPQGESLDDWISDYQRSTEQKEQTAANFNEKF 262
            .| :.:.|..|...::..:.||:          ..:..||::   :::|:     :.|...:.:|
  Rat   281 EL-ELVAPAQARLTKEHRWGSAL----------LSRNHSLEE---EFERA-----KAAVESDTEF 326

  Fly   263 WERLQDEWQKLADENEHPWLSEYNDNMDAY---------KEYEFAEGNPMSDVENPFEKGKEYLS 318
            |:::|.||:::|..|   |:||   |.:|.         |.|.|...||..|....||:|.:.|.
  Rat   327 WDKMQAEWEEMARRN---WISE---NQEAQNQVTVSASEKGYYFHTENPFKDWPGAFEEGLKRLK 385

  Fly   319 KGDIPSAVLCFEVAAKKQPERAEVWQLLGTSQTENEMDPQAIAALKRAYDLQPDNQQVLMALAAC 383
            :||:|..:|..|.|..:.|..||.||.||.:|.|||.:..||.||:|..:|||:|.:.|||||..
  Rat   386 EGDLPVTILFMEAAILQDPGDAEAWQFLGITQAENENEQAAIVALQRCLELQPNNLKALMALAVS 450

  Fly   384 YTNEGLQNNAVRMLCNWLTVHPKYQHLVAAHPELQAEGTSLASSLIGPSKLRDLQQIYLEAVRQH 448
            |||...|.:|...|.||:..:|||::||............::.|.:..|.|..::.:||||..|:
  Rat   451 YTNTSHQQDACEALKNWIKQNPKYKYLVKNKKGSPGLTRRMSKSPVDSSVLEGVKDLYLEAAHQN 515

  Fly   449 PSEVDAEVQDALGVLYNLSGEFDKAVDCYQSALQVDPQNAKTWNRLGASLANGSRSVEAVEAYQQ 513
            ...:|.::|..||||::|||||::|:|.:.:||.|.|::...||||||:||||.||.||||||.:
  Rat   516 GDMIDPDLQTGLGVLFHLSGEFNRAIDAFNAALTVRPEDYSLWNRLGATLANGDRSEEAVEAYTR 580

  Fly   514 ALQLQPGFIRVRYNVGVCCMNLKAYKEAVEHLLTALTMQAHTNAARELPNAAMAATFRGQNQMSE 578
            ||::||||||.|||:|:.|:||.||:|||.:.||||::|..:...:::|:.|          :|.
  Rat   581 ALEIQPGFIRSRYNLGISCINLGAYREAVSNFLTALSLQRKSRNQQQVPHPA----------ISG 635

  Fly   579 SIWSTLKMVISLMGRSDLQSYVSDRNLAALNEAF 612
            :||:.|::.:|||.:.:|....:..:|..|..||
  Rat   636 NIWAALRIALSLMDQPELFQAANLGDLDVLLRAF 669

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pex5	NP_726771.1	LapB	310..561	CDD:442196	116/250 (46%)
		TPR repeat	310..334	CDD:276809	10/23 (43%)
		TPR repeat	339..369	CDD:276809	15/29 (52%)
		TPR repeat	374..397	CDD:276809	10/22 (45%)
		TPR repeat	454..482	CDD:276809	13/27 (48%)
		TPR repeat	487..517	CDD:276809	20/29 (69%)
		TPR repeat	522..549	CDD:276809	16/26 (62%)
Pex5l	XP_063137479.1	None