DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG14814 and CG11322

DIOPT Version :9

Sequence 1:	NP_569947.2	Gene:	CG14814 / 31139	FlyBaseID:	FBgn0023515	Length:	1052	Species:	Drosophila melanogaster
Sequence 2:	NP_609071.2	Gene:	CG11322 / 33949	FlyBaseID:	FBgn0031856	Length:	480	Species:	Drosophila melanogaster

Alignment Length:	496	Identity:	124/496 - (25%)
Similarity:	210/496 - (42%)	Gaps:	83/496 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   564 HIDEDRWRKLIDSDSGTDASDDEDADATFSESGSDSDSDKDKENKQKRGDLTYLDLSKDEVEVIS 628
            ::||...::..||.|.::...:||     |....|.:..:.:...:||..|.||:|. |::.::.
  Fly    28 NLDEMSIQQFSDSSSQSEGDGEED-----SNDADDEEYQQPEWTGRKRPPLVYLELG-DKIIIVR 86

  Fly   629 NPDQDSPSPKCHRRLDDILRSCRASVKAKLPATPVQQPNIRRQLFTPNAGFENDNQAKEIVNRAL 693
            |..|  |:.|..   ||:      .:|.|:.......|: ||:|:.|...::...:..|.:|
  Fly    87 NEPQ--PNVKLE---DDV------QLKTKMHKFLGLIPS-RRKLYNPAVVYDMKPEDIENIN--- 136

  Fly   694 DLDMLDELESDYLPGTPVHRRVQEVK-------KKLGIGQQGQTTPHESPILKLLTPKTAPPKG- 750
              .:::...:...|.||...:....|       .||.:....:.||.||         .|..|.
  Fly   137 --CVVNSSHASAEPFTPSAEQPIRPKTMMTSTWSKLNLSNIDEPTPEES---------QAKSKND 190

  Fly   751 ------------TAPPKTSAPPKVSTPPKSTKQIPKPRKQKDLSPVASGGKC--------GFLKS 795
                        ..|.....|..:...|...:.....|:.|...|      |        ||::|
  Fly   191 FELWSIAFSFDQCTPDLHKEPIDLIDLPNEEQLAANCRRHKSSVP------CLERHPKFYGFVRS 249

  Fly   796 LEGQVSRDRADNEAFFYRE-NFARNKDQLAQHLYKMYNAQVFNNELDVPITWSKLLRNTAGRCMN 859
            |...:|.:.....|..||: ||...|..||:.|:.::|..:|:..|.|||.|...:..   ||..
  Fly   250 LSPSISLNMCHPLALTYRQNNFKICKVALAKVLFNIFNHAIFHCGLQVPIVWKHAMHT---RCTC 311

  Fly   860 KRKLN---QRSSVVELSVKVLTTADRLRCTLIHELCHAAAWVFNGEGGHGRVWKMWAQRANDKFP 921
            :..::   :|.:.:.|...:.|||:.:|| |:||:||.||:|||.|.|||...:.||.:|....|
  Fly   312 QLTVDAHGKRRAKILLLRSIKTTAELIRC-LLHEMCHVAAFVFNRELGHGDNCRRWAYQAKMALP 375

  Fly   922 DLPQIKVCHNYSIEFKYTYKCLSCDKASHAHSRSRKVEDLRCRICRGPITL-FLNKKDKQGNTVS 985
            :.|.|:  .|....||||  |..|.:.|:..: ...:::|||..|:..::: .:.|.:....|.|
  Fly   376 EAPTIE--DNCIDSFKYT--CTMCTRCSYGVA-DLSMQNLRCYYCQFEVSVKNVWKSEMYDWTRS 435

  Fly   986 TPAGEAKGFAKFVKDNF-QRHKRDNMTAAQVMRILSVEYAK 1025
            .|.  ...|..|:.|.: |..::...|.:..|.:|:.|:.:
  Fly   436 DPT--MTPFKCFIWDRYLQLGEQGANTHSTNMALLNEEFMR 474

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14814	NP_569947.2	SprT	821..973	CDD:214794	51/155 (33%)
CG11322	NP_609071.2	DUF45	278..422	CDD:302795	51/152 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45455774
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3854
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR23099
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840