DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment prage and RNH70

DIOPT Version :9

Sequence 1:	NP_001188528.1	Gene:	prage / 31136	FlyBaseID:	FBgn0283741	Length:	852	Species:	Drosophila melanogaster
Sequence 2:	NP_011792.1	Gene:	RNH70 / 853193	SGDID:	S000003508	Length:	553	Species:	Saccharomyces cerevisiae

Alignment Length:	171	Identity:	76/171 - (44%)
Similarity:	116/171 - (67%)	Gaps:	13/171 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   669 DFVRT---EHRGSGEDEPAVYALDCEMSYTGRGLDVTKVSLVALNGQLVYEHFVRPVCDIIDYNT 730
            |:|:|   .|.||     .::||||||..:.:||.:|::|||..:.:::||..|:|...|:||.|
Yeast   211 DWVQTVDFTHGGS-----HIFALDCEMCLSEQGLVLTRISLVNFDNEVIYEELVKPDVPIVDYLT 270

  Fly   731 QYSGITETDLCSGA-KSLAEVQRDLLQLITADTILIGHGLENDLRALRLVHNTLIDTSISFPHCN 794
            :||||||..|..|| |:|.|||:|||::|:...|||||.|:|||:.::|.|..::||:|.:.|..
Yeast   271 RYSGITEEKLTVGAKKTLREVQKDLLKIISRSDILIGHSLQNDLKVMKLKHPLVVDTAIIYHHKA 335

  Fly   795 GFPYRRALRHLTKVHLKRDIQAGDGTTGHSSFEDSRACMEL 835
            |.|::.:|::|::..|.:.||.|:    |.|.||:|||:||
Yeast   336 GDPFKPSLKYLSETFLNKSIQNGE----HDSVEDARACLEL 372

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
prage	NP_001188528.1	PH-like	<614..650	CDD:302622
		DnaQ	675..>837	CDD:223916	73/162 (45%)
		REX1_like	686..837	CDD:99848	70/151 (46%)
RNH70	NP_011792.1	REX1_like	226..374	CDD:99848	70/151 (46%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0847
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002085
OrthoInspector	1	1.000	-	-		otm46628
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12801
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2254
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	7	6.900