Protein Alignment prage and ISG20L2

DIOPT Version :10

• Sequence 1: NP_001188528.1
• Gene: prage / 31136
• FlyBaseID: FBgn0283741
• Length: 852
• Species: Drosophila melanogaster
• Sequence 2: NP_001290024.1
• Gene: ISG20L2 / 81875
• HGNCID: 25745
• Length: 353
• Species: Homo sapiens
• Alignment Length: 180
• Identity: 64/180 - (35%)
• Similarity: 101/180 - (56%)
• Gaps: 26/180 - (14%)

  Fly   673 TEHRGSGEDEP---AVYALDCEMSYTG-RG--LDVTKVSLVALNGQLVYEHFVRPVCDIIDYNTQ 731
            :|::.||..:.   .:.|:||||..|| :|  ..:.:.|:|..||.::|:.::.|.|.|:||.|:
Human   164 SENKCSGASQKLPRKMVAIDCEMVGTGPKGHVSSLARCSIVNYNGDVLYDEYILPPCHIVDYRTR 228

  Fly   732 YSGITETDLCSGAKSLAEVQRDLLQLITADTILIGHGLENDLRALRLVHNTLI--DTSISFPHCN 794
            :|||.:..:.: |......:..:|:::|. .|::||.:.||.:||:..|...:  ||| ..|..|
Human   229 WSGIRKQHMVN-ATPFKIARGQILKILTG-KIVVGHAIHNDFKALQYFHPKSLTRDTS-HIPPLN 290

  Fly   795 GFPYRRA---------LRHLTKVHLKRDIQAGDGTTGHSSFEDSRACMEL 835
                |:|         |:||||..|.||||.  |.:||||.||::|.|||
Human   291 ----RKADCPENATMSLKHLTKKLLNRDIQV--GKSGHSSVEDAQATMEL 334

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
prage	NP_001188528.1	PH-like	<614..650	CDD:473070
		REX1_like	686..837	CDD:99848	61/164 (37%)
ISG20L2	NP_001290024.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..93
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	125..172		3/7 (43%)
		ISG20	180..336	CDD:99852	61/164 (37%)