DRSC/TRiP Functional Genomics Resources

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Protein Alignment prage and ISG20L2

DIOPT Version :9

Sequence 1:NP_001188528.1 Gene:prage / 31136 FlyBaseID:FBgn0283741 Length:852 Species:Drosophila melanogaster
Sequence 2:NP_001290024.1 Gene:ISG20L2 / 81875 HGNCID:25745 Length:353 Species:Homo sapiens


Alignment Length:180 Identity:64/180 - (35%)
Similarity:101/180 - (56%) Gaps:26/180 - (14%)


- Green bases have known domain annotations that are detailed below.


  Fly   673 TEHRGSGEDEP---AVYALDCEMSYTG-RG--LDVTKVSLVALNGQLVYEHFVRPVCDIIDYNTQ 731
            :|::.||..:.   .:.|:||||..|| :|  ..:.:.|:|..||.::|:.::.|.|.|:||.|:
Human   164 SENKCSGASQKLPRKMVAIDCEMVGTGPKGHVSSLARCSIVNYNGDVLYDEYILPPCHIVDYRTR 228

  Fly   732 YSGITETDLCSGAKSLAEVQRDLLQLITADTILIGHGLENDLRALRLVHNTLI--DTSISFPHCN 794
            :|||.:..:.: |......:..:|:::|. .|::||.:.||.:||:..|...:  ||| ..|..|
Human   229 WSGIRKQHMVN-ATPFKIARGQILKILTG-KIVVGHAIHNDFKALQYFHPKSLTRDTS-HIPPLN 290

  Fly   795 GFPYRRA---------LRHLTKVHLKRDIQAGDGTTGHSSFEDSRACMEL 835
                |:|         |:||||..|.||||.  |.:||||.||::|.|||
Human   291 ----RKADCPENATMSLKHLTKKLLNRDIQV--GKSGHSSVEDAQATMEL 334

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
prageNP_001188528.1 PH-like <614..650 CDD:302622
DnaQ 675..>837 CDD:223916 63/178 (35%)
REX1_like 686..837 CDD:99848 61/164 (37%)
ISG20L2NP_001290024.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..93
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 125..172 3/7 (43%)
ISG20 180..336 CDD:99852 61/164 (37%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C165154933
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0847
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
43.740

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