DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment prage and Aen

DIOPT Version :9

Sequence 1:	NP_001188528.1	Gene:	prage / 31136	FlyBaseID:	FBgn0283741	Length:	852	Species:	Drosophila melanogaster
Sequence 2:	NP_001347638.1	Gene:	Aen / 68048	MGIID:	1915298	Length:	336	Species:	Mus musculus

Alignment Length:	159	Identity:	54/159 - (33%)
Similarity:	87/159 - (54%)	Gaps:	15/159 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   687 ALDCEMSYT---GRGLDVTKVSLVALNGQLVYEHFVRPVCDIIDYNTQYSGITETDLCSGAKSLA 748
            |:||||..|   ||..::.:.|:|:.:|.::|:.::||...|:||.|::||||...: ..|....
Mouse   111 AIDCEMVGTGPQGRVSELARCSVVSYSGDVLYDKYIRPEMPIVDYRTRWSGITRQHM-HKAIPFQ 174

  Fly   749 EVQRDLLQLITADTILIGHGLENDLRALRLVH-------NTLIDTSISFPHCNGFPYRRALRHLT 806
            ..|:::|:|:.. .:::||.|.||.:||:.||       .|.:...:|.| .:....|.:|:.|.
Mouse   175 VAQKEILKLLKG-KVVVGHALHNDFQALKYVHPRSQTRDTTYVPNLLSQP-SSLIRTRVSLKDLA 237

  Fly   807 KVHLKRDIQAGDGTTGHSSFEDSRACMEL 835
            ...|.:.||.|.  .||||.||:...|||
Mouse   238 LNLLHKKIQVGH--QGHSSVEDAMTAMEL 264

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
prage	NP_001188528.1	PH-like	<614..650	CDD:302622
		DnaQ	675..>837	CDD:223916	54/159 (34%)
		REX1_like	686..837	CDD:99848	54/159 (34%)
Aen	NP_001347638.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..37
		Nucleolar localization signal. /evidence=ECO:0000250	25..33
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	56..102
		DnaQ_like_exo	110..266	CDD:324557	54/159 (34%)
		Nuclear localization signal. /evidence=ECO:0000250	164..187		4/24 (17%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	276..336
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167845407
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0847
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.740