Protein Alignment prage and AEN

DIOPT Version :9

• Sequence 1: NP_001188528.1
• Gene: prage / 31136
• FlyBaseID: FBgn0283741
• Length: 852
• Species: Drosophila melanogaster
• Sequence 2: NP_073604.3
• Gene: AEN / 64782
• HGNCID: 25722
• Length: 325
• Species: Homo sapiens
• Alignment Length: 202
• Identity: 62/202 - (30%)
• Similarity: 96/202 - (47%)
• Gaps: 33/202 - (16%)

  Fly   676 RGSGEDEPAVYALDCEMSYT---GRGLDVTKVSLVALNGQLVYEHFVRPVCDIIDYNTQYSGITE 737
            :.||.......|:||||..|   ||..::.:.|:|:.:|.::|:.::||...|.||.|::||||.
Human   101 KASGPLPSKCVAIDCEMVGTGPRGRVSELARCSIVSYHGNVLYDKYIRPEMPIADYRTRWSGITR 165

  Fly   738 TDLCSGAKSLAEVQRDLLQLITADTILIGHGLENDLRALRLVH-------NTLIDTSISFP--HC 793
            ..: ..|......|:::|:|:.. .:::||.|.||.:||:.||       .|.:...:|.|  |.
Human   166 QHM-RKAVPFQVAQKEILKLLKG-KVVVGHALHNDFQALKYVHPRSQTRDTTYVPNFLSEPGLHT 228

  Fly   794 NGFPYRRALRHLTKVHLKRDIQAGDGTTGHSSFEDSRACMEL--------------MLWRVNREL 844
            ..   |.:|:.|....|.:.||.|.  .||||.||:...|||              .||....:.
Human   229 RA---RVSLKDLALQLLHKKIQVGQ--HGHSSVEDATTAMELYRLVEVQWEQQEARSLWTCPEDR 288

  Fly   845 DPAWSWD 851
            :|..|.|
Human   289 EPDSSTD 295

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
prage	NP_001188528.1	PH-like	<614..650	CDD:302622
		DnaQ	675..>837	CDD:223916	57/186 (31%)
		REX1_like	686..837	CDD:99848	55/176 (31%)
AEN	NP_073604.3	Nucleolar localization signal	27..35
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	85..105		1/3 (33%)
		DnaQ	106..314	CDD:223916	60/197 (30%)
		DnaQ_like_exo	111..267	CDD:299142	55/162 (34%)
		Nuclear localization signal. /evidence=ECO:0000269|PubMed:18264133	165..188		4/24 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	281..325		5/15 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165154937
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0847
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.740