DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment prage and Pan2

DIOPT Version :9

Sequence 1:	NP_001188528.1	Gene:	prage / 31136	FlyBaseID:	FBgn0283741	Length:	852	Species:	Drosophila melanogaster
Sequence 2:	NP_001382635.1	Gene:	Pan2 / 408200	RGDID:	1303301	Length:	1207	Species:	Rattus norvegicus

Alignment Length:	191	Identity:	52/191 - (27%)
Similarity:	87/191 - (45%)	Gaps:	29/191 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   658 GSVVGVNGPYYDFVRTEHRGSGEDEPAVYALDCEMSYTGRGLDVTKVSLVALNGQ----LVYEHF 718
            |.:||::.   :||..     .|:|..:.:...:.:.....:.|.:::.|...|.    ...:.:
  Rat   977 GDLVGLDA---EFVTL-----NEEEAELRSDGTKSTIKPSQMSVARITCVRGQGPNEGIPFIDDY 1033

  Fly   719 VRPVCDIIDYNTQYSGITETDLCS--GAKSLAEVQRDLLQ---LITADTILIGHGLENDLRALRL 778
            :.....::||.||||||...||.:  .:|.|..::...|:   ||......:||||:.|.|.:.|
  Rat  1034 ISTQEQVVDYLTQYSGIKPGDLDAKISSKHLTTLKSTYLKLRFLIDIGVKFVGHGLQKDFRVINL 1098

  Fly   779 V--HNTLIDTSISFPHCNGFPYRR--ALRHLTKVHLKRDIQAGDGTTGHSSFEDSRACMEL 835
            :  .:.::||...| |   .|.:|  :||.|....|...||   |.| |.|.||:|..::|
  Rat  1099 MVPKDQVLDTVYLF-H---MPRKRMISLRFLAWYFLDLKIQ---GET-HDSIEDARTALQL 1151

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
prage	NP_001188528.1	PH-like	<614..650	CDD:302622
		DnaQ	675..>837	CDD:223916	47/174 (27%)
		REX1_like	686..837	CDD:99848	45/163 (28%)
Pan2	NP_001382635.1	WD 1. /evidence=ECO:0000255\|HAMAP-Rule:MF_03182	153..193
		WD 2. /evidence=ECO:0000255\|HAMAP-Rule:MF_03182	195..231
		WD 3. /evidence=ECO:0000255\|HAMAP-Rule:MF_03182	244..280
		WD 4. /evidence=ECO:0000255\|HAMAP-Rule:MF_03182	328..367
		Linker. /evidence=ECO:0000255\|HAMAP-Rule:MF_03182	368..484
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0847
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810