DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment prage and ISG20

DIOPT Version :9

Sequence 1:	NP_001188528.1	Gene:	prage / 31136	FlyBaseID:	FBgn0283741	Length:	852	Species:	Drosophila melanogaster
Sequence 2:	NP_001290162.1	Gene:	ISG20 / 3669	HGNCID:	6130	Length:	181	Species:	Homo sapiens

Alignment Length:	171	Identity:	62/171 - (36%)
Similarity:	94/171 - (54%)	Gaps:	24/171 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   677 GSGEDEPAVYALDCEMSYTG--RGLDVTKVSLVALNGQLVYEHFVRPVCDIIDYNTQYSGITETD 739
            ||.|    |.|:||||...|  |...:.:.|||.::|.::|:.|:||..:|.||.|:.||:|...
Human     3 GSRE----VVAMDCEMVGLGPHRESGLARCSLVNVHGAVLYDKFIRPEGEITDYRTRVSGVTPQH 63

  Fly   740 LCSGAKSLAEVQRDLLQLITADTILIGHGLENDLRALR--LVHNTLIDTS--------ISFPHCN 794
            :. ||...|..:.::|||:.. .:::||.|::|.:||:  :...|:.|||        ....||.
Human    64 MV-GATPFAVARLEILQLLKG-KLVVGHDLKHDFQALKEDMSGYTIYDTSTDRLLWREAKLDHCR 126

  Fly   795 GFPYRRALRHLTKVHLKRDIQAGDGTTGHSSFEDSRACMEL 835
                |.:||.|::..|.:.||  :...||||.||:||.|||
Human   127 ----RVSLRVLSERLLHKSIQ--NSLLGHSSVEDARATMEL 161

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
prage	NP_001188528.1	PH-like	<614..650	CDD:302622
		DnaQ	675..>837	CDD:223916	62/171 (36%)
		REX1_like	686..837	CDD:99848	58/162 (36%)
ISG20	NP_001290162.1	DnaQ_like_exo	8..163	CDD:415823	58/162 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0847
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810