DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment prage and Aen

DIOPT Version :9

Sequence 1:	NP_001188528.1	Gene:	prage / 31136	FlyBaseID:	FBgn0283741	Length:	852	Species:	Drosophila melanogaster
Sequence 2:	NP_001101957.1	Gene:	Aen / 361594	RGDID:	1305051	Length:	332	Species:	Rattus norvegicus

Alignment Length:	290	Identity:	86/290 - (29%)
Similarity:	130/290 - (44%)	Gaps:	73/290 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   584 VPVERSL----SKPCARCKRHFLVDELTGQYLTHEECQYHSGKYQRYYDGVSHGRWTCCNEGEES 644
            || |.||    :|..|| :||                :..|.::||:.     .|.....|.|..
  Rat     6 VP-ESSLTSLKTKDVAR-RRH----------------KRRSRQHQRFM-----ARKALLQEQESL 47

  Fly   645 S----PGCC--------------LGDRHVWSGSVVGVNG-----PYYDFVRTEHRGSGEDEPAVY 686
            |    ||.|              .|:|...:.:..|..|     |    |..|...||   |:.|
  Rat    48 SMVPGPGLCPLPSPTQTPAGTEASGNRKQRTKARSGSKGLCSKRP----VPREAPSSG---PSKY 105

  Fly   687 -ALDCEMSYT---GRGLDVTKVSLVALNGQLVYEHFVRPVCDIIDYNTQYSGITETDLCSGAKSL 747
             |:||||..|   ||..::.:.|:|:.:|.::|:.::||...|:||.|::||||...: ..|...
  Rat   106 VAIDCEMVGTGPQGRVSELARCSVVSYSGDVLYDKYIRPEMPIVDYRTRWSGITRQHM-HKAIPF 169

  Fly   748 AEVQRDLLQLITADTILIGHGLENDLRALRLVH--NTLIDTSISFPHCNGFP-----YRRALRHL 805
            ...|:::|:|:.. .:::||.|.||.:||:.||  :.:.||:. .|:....|     .|.:|:.|
  Rat   170 QVAQKEILKLLKG-KVVVGHALHNDFQALKYVHPGSQIRDTTY-VPNLLSQPSSLTRARVSLKDL 232

  Fly   806 TKVHLKRDIQAGDGTTGHSSFEDSRACMEL 835
            ....|.:.||.|.  .||||.||:...|||
  Rat   233 ALNLLHKKIQVGH--HGHSSVEDAMTAMEL 260

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
prage	NP_001188528.1	PH-like	<614..650	CDD:302622	10/53 (19%)
		DnaQ	675..>837	CDD:223916	59/172 (34%)
		REX1_like	686..837	CDD:99848	56/161 (35%)
Aen	NP_001101957.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..102		29/125 (23%)
		Nucleolar localization signal. /evidence=ECO:0000250\|UniProtKB:Q8WTP8	21..29		3/24 (13%)
		DnaQ	102..>263	CDD:223916	57/164 (35%)
		DnaQ_like_exo	106..262	CDD:299142	55/160 (34%)
		Nuclear localization signal. /evidence=ECO:0000250\|UniProtKB:Q8WTP8	160..183		4/24 (17%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	272..332
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166348817
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0847
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740