DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment prage and Trex2

DIOPT Version :9

Sequence 1:	NP_001188528.1	Gene:	prage / 31136	FlyBaseID:	FBgn0283741	Length:	852	Species:	Drosophila melanogaster
Sequence 2:	NP_036037.1	Gene:	Trex2 / 24102	MGIID:	1346343	Length:	236	Species:	Mus musculus

Alignment Length:	194	Identity:	42/194 - (21%)
Similarity:	64/194 - (32%)	Gaps:	75/194 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly   691 EMSYTGRGLDVTKVSLVAL--------NGQLV--YEHFVR----PVCDI----IDYNTQYSGITE 737
            |..:|.:..::|.:|..:|        ||.:|  .:.|:.    |:|.:    .||:...
Mouse    67 ERPFTAKASEITGLSSESLMHCGKAGFNGAVVRTLQGFLSRQEGPICLVAHNGFDYDFPL----- 126

  Fly   738 TDLCSGAKSLAEVQRDLLQLITADTILIGHGLENDLRALRLVHNTLIDTSISFPHCNGFPYRRAL 802
              ||:      |:||            :|..|..|        ...:||   .|...|..  ||.
Mouse   127 --LCT------ELQR------------LGAHLPQD--------TVCLDT---LPALRGLD--RAH 158

  Fly   803 RHLTKVH----------LKRDIQAGDGTTGHSSFEDSRACMELMLWRVNRELDPAW------SW 850
            .|.|:..          ..|..|| :.:..||:..|....:.:.|.|....|  ||      ||
Mouse   159 SHGTRAQGRKSYSLASLFHRYFQA-EPSAAHSAEGDVHTLLLIFLHRAPELL--AWADEQARSW 219

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
prage	NP_001188528.1	PH-like	<614..650	CDD:302622
		DnaQ	675..>837	CDD:223916	35/173 (20%)
		REX1_like	686..837	CDD:99848	35/173 (20%)
Trex2	NP_036037.1	TREX1_2	10..204	CDD:99839	36/175 (21%)
Trex2	NP_036037.1	Substrate binding. /evidence=ECO:0000250	16..17
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0847
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900