Protein Alignment prage and Rexo4

DIOPT Version :10

• Sequence 1: NP_001188528.1
• Gene: prage / 31136
• FlyBaseID: FBgn0283741
• Length: 852
• Species: Drosophila melanogaster
• Sequence 2: NP_997117.2
• Gene: Rexo4 / 227656
• MGIID: 2684957
• Length: 432
• Species: Mus musculus
• Alignment Length: 509
• Identity: 101/509 - (19%)
• Similarity: 168/509 - (33%)
• Gaps: 183/509 - (35%)

  Fly   383 QKTCDSSSSSALSSPTSSATTSATSSPTNSPTSYPRANGNRKRIEAALEWRREQELGRQNANFLV 447
            :|....|.:.|.|....|...:....|..:|.::.:            .|:..|||.:|.:....
Mouse    47 KKKFRKSKALAGSGVPGSHPAAVAGRPPKAPENFSQ------------NWKALQELLKQKSQAAE 99

  Fly   448 PPLRQYEQLEFDDK---TVVQQLRRHIIDNHLLRVYGFPVDSVVHEGAIEIFKCMPHMSFAAALA 509
            .||..    :.|||   .::||.|:
Mouse   100 KPLVS----QMDDKMHPQIIQQNRK---------------------------------------- 120

  Fly   510 ETAQAVTVINYHDGLTNRAEEEVANSTDSGNSSPQSLDSESGGEWSGSECESSNSSSSSAGEAAL 574
                                              ::.|...|.:....:.:|:..|.:||
Mouse   121 ----------------------------------KASDKSKGDKQRTEKAKSTRGSVTSA----- 146

  Fly   575 GLELKYCHFVPVERSLSKPCARCKRHFLVDELTGQYLTHEECQYHSGKYQRYYDGVSH-----GR 634
                      |.:|.:..|         ..:.:|..      |....|.:.|.|..||     .:
Mouse   147 ----------PTDRKILVP---------PTDTSGTE------QKKGAKKRTYSDISSHQGALKPK 186

  Fly   635 WTCCNEG---EESSPGCCLGDRHVW-----SGSVVGVNGPYYDFVRTEHRG------SGEDEPA- 684
            |......   .:.:|    .:..:|     ...:....||....:..:..|      |.|.|.|
Mouse   187 WKATEAAVILNQPTP----TEEDIWFDDVDPDDIEDAIGPEAAMLVRKRLGQKKRTISLEKEQAF 247

  Fly   685 -----VYALDCEMSYTG-RGLD--VTKVSLVALNGQLVYEHFVRPVCDIIDYNTQYSGITETDLC 741
                 ..||||||...| :|.:  ..:||:|...|:.||:.:|:|...:.||.|..|||...:|.
Mouse   248 GGLTKALALDCEMVGVGPKGEESIAARVSIVNQYGKCVYDKYVKPTEPVTDYRTAVSGIRPENLK 312

  Fly   742 SGAKSLAEVQRDLLQLITADTILIGHGLENDLRALRLVH--NTLIDTSISFPHCNGFPYRR---- 800
            .| :....|::::.:::.. .||:||.|.|||:.|.|.|  ..:.||. .|.     |:|.
Mouse   313 QG-EEFEVVKKEVAEMLKG-RILVGHALHNDLKVLFLDHPKKKIRDTQ-KFK-----PFRSRVKS 369

  Fly   801 ---ALRHLTKVHLKRDIQAGDGTTGHSSFEDSRACMELMLWRVNRELDPAWSWD 851
               :|:.|::..|...:|..:    |.|.:|::|.|.|.: .|.||      |:
Mouse   370 GRPSLKRLSEKILGIRVQQAE----HCSIQDAQAAMRLYV-MVKRE------WE 412

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
prage	NP_001188528.1	PH-like	<614..650	CDD:473070	8/43 (19%)
		REX1_like	686..837	CDD:99848	51/162 (31%)
Rexo4	NP_997117.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	42..177		34/249 (14%)
		REX4_like	254..404	CDD:99847	50/161 (31%)