Protein Alignment prage and LOC101929627

DIOPT Version :10

• Sequence 1: NP_001188528.1
• Gene: prage / 31136
• FlyBaseID: FBgn0283741
• Length: 852
• Species: Drosophila melanogaster
• Sequence 2: XP_005251179.1
• Gene: LOC101929627 / 101929627
• -ID: -
• Length: 675
• Species: Homo sapiens
• Alignment Length: 622
• Identity: 174/622 - (27%)
• Similarity: 276/622 - (44%)
• Gaps: 136/622 - (21%)

  Fly   315 AATPC-------TGQKAKQGNAKWRQQQPNPSSNNQQQ------QMQQ--------QMQQQKRGR 358
            |..||       ..:|..:..|....:.|.||....|.      ||.:        |.:.|.||.
Human    96 ATAPCWFPPGYPEAKKVAEEAALEAPEFPLPSHQPAQSFGLWVPQMHKQASAFVDIQAEPQNRGP 160

  Fly   359 NKKPGKWSNNIIDN---PNSNHGGS----SQQKTCDSSSSSALSSPTSSATTSATSSPTNSPTSY 416
            ...|. |...:.::   | :..|.:    :..:..:..|...:|:|....|.:.:|||. ..|.|
Human   161 AVPPA-WPKMVTESCYFP-AQRGSACRLPAAPRLTERPSGVRISAPRKRKTIAHSSSPC-LVTGY 222

  Fly   417 PRANGNRKRIEAALEWRREQELGRQNANFLVPPLRQYEQLEFDDKTVVQQLRRHIIDNH------ 475
              .:..|.|:.::.:..|..::|||       |.:...:.....||......:.|:...
Human   223 --TDAKRTRVASSSQRSRGSKVGRQ-------PGKTRNRSGMACKTTATTSSKRIVRRASLPSLS 278

  Fly   476 -----LLRVYGFPVDSVVHEGAIEIF--KCMPHMSFAAALAETAQAVTVINYHDGLTNRAEEEVA 533
                 :||..|..|.:|:..|.:::|  :|   :.|.|:..|..:  ..:|         ||:||
Human   279 LKKPIILRSSGCQVPTVLRRGYLQLFTEEC---LKFCASKQEAEE--KALN---------EEKVA 329

  Fly   534 -----NSTDSGNSSPQSLDSESGGEWSGSECESSNSSSSSAGEAALGLELKYCHFVPVERSLS-- 591
                 |.....|....:|....|         .:.||......|||...|:  .|:..:..|.
Human   330 YDCSPNKNRYLNVVLNTLKRLKG---------LTPSSMPGLSRAALYSRLQ--EFLLTQDQLKEN 383

  Fly   592 ----------------------------KPCARCKRHFLVDELTGQYLTHEECQYHSGKYQRYYD 628
                                        :.|.||...:||.. :|:.:..:.|.||.|:.:.  .
Human   384 GYPFPHPERPGGAVLFTGQGKGPGDSSCRVCCRCGTEYLVSS-SGRCVRDQLCYYHWGRVRS--S 445

  Fly   629 GVSHGR---WTCCNEGEESSPGCCLGDRHVWSGSVVGVNGPYYDFVRTEHRGSGEDE-PAVYALD 689
            .|:.||   :||| .....|.||.:..:||..|....::|    ||.|..:....|. |.:||||
Human   446 QVAGGRVSQYTCC-AAAPGSVGCQVAKQHVRDGRKESLDG----FVETFKKELSRDAYPGIYALD 505

  Fly   690 CEMSYTGRGLDVTKVSLVALNGQLVYEHFVRPVCDIIDYNTQYSGITETDLCSGAKSLAEVQRDL 754
            |||.||..||::|:|::|..:.::||:.||:|..:|:||||::||:||.|:...:.:|.:||..|
Human   506 CEMCYTTHGLELTRVTVVDADMRVVYDTFVKPDNEIVDYNTRFSGVTEADVAKTSITLPQVQAIL 570

  Fly   755 LQLITADTILIGHGLENDLRALRLVHNTLIDTSISFPHCNGFPYRRALRHLTKVHLKRDIQAGDG 819
            |...:|.||||||.||:||.||:|:|:|::||::.|||..||||:|:||:|...:|.:.||  |.
Human   571 LSFFSAQTILIGHSLESDLLALKLIHSTVVDTAVLFPHYLGFPYKRSLRNLAADYLAQIIQ--DS 633

  Fly   820 TTGHSSFEDSRACMELMLWRV---------NRELDPA 847
            ..||:|.||:.||::|::|:|         :|...||
Human   634 QDGHNSSEDANACLQLVMWKVRQRAQIQPRHRSASPA 670

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
prage	NP_001188528.1	PH-like	<614..650	CDD:473070	13/38 (34%)
		REX1_like	686..837	CDD:99848	75/150 (50%)
LOC101929627	XP_005251179.1	EloA-BP1	281..401	CDD:464914	28/144 (19%)
		REX1_like	502..651	CDD:99848	75/150 (50%)