DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment prage and Trex1

DIOPT Version :9

Sequence 1:	NP_001188528.1	Gene:	prage / 31136	FlyBaseID:	FBgn0283741	Length:	852	Species:	Drosophila melanogaster
Sequence 2:	NP_001020160.1	Gene:	Trex1 / 100049583	RGDID:	1311998	Length:	316	Species:	Rattus norvegicus

Alignment Length:	268	Identity:	47/268 - (17%)
Similarity:	81/268 - (30%)	Gaps:	89/268 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   228 YGRQFVHSSCIEDKLLGHHNPGHRNSTSSDATSEDIDSSSELPNK-----SKGNSC-AGSIHASG 286
            |.:..:...|    ||..|.....||:.|:.....:.....:.:|     :.|..| :|:...:|
  Rat    26 YSQPKITELC----LLAVHRHALENSSMSEGQPPPVPKPPRVVDKLSLCIAPGKPCSSGASEITG 86

  Fly   287 GSKSRSKRHQKQSGQQT----------RNPD------HNGQR------------TGAATPCTGQK 323
            .:.:..:.|.:|.....          |.|.      |||.|            ....:|..|..
  Rat    87 LTTAGLEAHGRQRFNDNLATLLQVFLQRQPQPCCLVAHNGDRYDFPLLQAELASLSVISPLDGTF 151

  Fly   324 AKQGNA--KWRQQQPNPSSNNQQQ---------------------------------QMQQQMQQ 353
            .....|  |..:|..:||.:..::                                 |.:.|...
  Rat   152 CVDSIAALKTLEQASSPSEHGPRKSYSLGSIYTRLYGQAPTDSHTAEGDVLALLSICQWKPQALL 216

  Fly   354 QKRGRNKKPGKWSNNIIDNPNSNHGGSSQQKTCDSSSSSALSSPTSSATTSATSSPTNS------ 412
            |...::.:|       .......:|.::   |..::|....::.|||...:|..||:|.
  Rat   217 QWVDKHARP-------FSTIKPMYGMAA---TTGTASPRLCAATTSSPLATANLSPSNGRSRGKR 271

  Fly   413 PTSYPRAN 420
            |||.|..|
  Rat   272 PTSPPPEN 279

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
prage	NP_001188528.1	PH-like	<614..650	CDD:302622
		DnaQ	675..>837	CDD:223916
		REX1_like	686..837	CDD:99848
Trex1	NP_001020160.1	TREX1_2	14..211	CDD:99839	29/188 (15%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0847
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900