Protein Alignment Adar and TAD1

DIOPT Version :10

• Sequence 1: NP_001368969.1
• Gene: Adar / 31130
• FlyBaseID: FBgn0026086
• Length: 681
• Species: Drosophila melanogaster
• Sequence 2: NP_011271.1
• Gene: TAD1 / 852608
• SGDID: S000003212
• Length: 400
• Species: Saccharomyces cerevisiae
• Alignment Length: 365
• Identity: 76/365 - (20%)
• Similarity: 142/365 - (38%)
• Gaps: 75/365 - (20%)

  Fly   334 VLAGI-VMTENMNFCEAKVISVSTGTKCV-SGEHMSVNGAVLNDSHAEIVSRRCLLKYLYAQLDL 396
            :|||: .:..:....:.:::|::||.|.: ..|.....|.:|:|.||||::.|.....|..::.
Yeast    56 ILAGVAAINRDGGANKIEILSIATGVKALPDSELQRSEGKILHDCHAEILALRGANTVLLNRIQ- 119

  Fly   397 QCNQATAYQSIFVRNTDGQYP--YKLKSGVHFHLYINTAPCGDARIFSPHEN----------DTG 449
              |...:....|:::.| :.|  :.||......|||:..|||||.:...::|          |:.
Yeast   120 --NYNPSSGDKFIQHND-EIPARFNLKENWELALYISRLPCGDASMSFLNDNCKNDDFIKIEDSD 181

  Fly   450 VDKHPNRKARGQLRTKIESGEGTIPVKSSDGIQTWDGVLQGQRLLTMSCSDKIARWNIVGIQGSL 514
            ..::.:|..:..||.::......:       ::|..|.......|:.|||||:.......:...|
Yeast   182 EFQYVDRSVKTILRGRLNFNRRNV-------VRTKPGRYDSNITLSKSCSDKLLMKQRSSVLNCL 239

  Fly   515 LSSIIE-PVYLHSIVLGSL-----LHPEHMYRAVCGRIEKSIQGLP--PPYHLNKPRLALVTSAE 571
            ...:.| ||:|..||:.:|     .|.|..:......::..|:.|.  .|::.:|
Yeast   240 NYELFEKPVFLKYIVIPNLEDETKHHLEQSFHTRLPNLDNEIKFLNCLKPFYDDK---------- 294

  Fly   572 PRNQAKAPNF--GINWTIGD--TELEVVNSLTG-----------RTIGGQVSRITKQAFFVKYGF 621
             .::...|..  .:...:.|  ||..::|.:..           :....||||..:...|
Yeast   295 -LDEEDVPGLMCSVKLFMDDFSTEEAILNGVRNGFYTKSSKPLRKHCQSQVSRFAQWELF----- 353

  Fly   622 LMANLPGILVRKVTTDY-GQTKANVKDYQIAKLELFSAFK 660
                      :|:..:| |.:....|..|..:.:|..|.|
Yeast   354 ----------KKIRPEYEGISYLEFKSRQKKRSQLIIAIK 383

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Adar	NP_001368969.1	DSRM_STRBP_RED-like_rpt1	105..167	CDD:380694
		DSRM_SF	213..>259	CDD:444671
		ADEAMc	306..677	CDD:214718	76/365 (21%)
TAD1	NP_011271.1	ADEAMc	22..400	CDD:214718	76/365 (21%)