DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Adar and adad2

DIOPT Version :9

Sequence 1:	NP_001368969.1	Gene:	Adar / 31130	FlyBaseID:	FBgn0026086	Length:	681	Species:	Drosophila melanogaster
Sequence 2:	NP_001072832.1	Gene:	adad2 / 780293	XenbaseID:	XB-GENE-6456955	Length:	438	Species:	Xenopus tropicalis

Alignment Length:	448	Identity:	126/448 - (28%)
Similarity:	190/448 - (42%)	Gaps:	88/448 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   264 KNAAAKAALASLCNISYSPMVVPQKNVPLPIDDKSSSMELPQIHADTIGRLVLEKFMEVIKGQEA 328
            |..||...|.|...:...|.:............:.|..:||  |......||.:.|..:::..|.
Frog    10 KQQAAILPLQSQQQLGIVPDLEEMNEEGTKTSSEVSQDKLP--HWQRCAVLVSDIFHSLLRDNEY 72

  Fly   329 YSRRKVLAGIVMTENMNFCEAK-----VISVSTGTKCVSGEHMSVNGAVLNDSHAEIVSRRCLLK 388
            ||.|.::|..::...:...:.|     |::..||..|..| ....:|.:::||||.:|:||.||:
Frog    73 YSHRNIVAAFILEREVRGDKVKDDIYAVVAFGTGDSCYQG-WQDYSGLLVHDSHALVVARRALLR 136

  Fly   389 YLYAQLDLQCNQATAYQS---------IFVRNTDGQYPYKLKSGVHFHLYINTAPCGDARIFSPH 444
            |||.||::       |||         ||..:...|. ..||..:..||||:....|..::..|
Frog   137 YLYKQLNM-------YQSDLPLAKEKCIFCPSQQSQM-LVLKPNIFLHLYISFTSEGSTQVSHP- 192

  Fly   445 ENDTGVDKHP----NRKARGQLRTKIESGEGTIPVKSSDGIQTWDGVLQ--GQRLLTMSCSDKIA 503
                .||..|    :..|:|.|          :||.        |..|.  ..|:..||..||:.
Frog   193 ----WVDLSPCVSLHVHAKGSL----------LPVS--------DCPLSVLAARVCCMSALDKLM 235

  Fly   504 RWNIVGIQGSLLSSIIEPVYLHSIVLGSLLHPEH--MYRAVCGRIEKSIQ-GLPPPYHLNKPRL- 564
            :||::|:||:|||..|:|:|:.|||.||....|.  :.:||..|::.|:. .|.|.|.::.|.:
Frog   236 KWNVLGVQGALLSQSIDPLYITSIVTGSSTEEEQDFLCKAVTERMKLSLDLSLFPSYSVHTPYIF 300

  Fly   565 ---ALVTSAEPRNQAKAPNFGINWTIGDTELEVVNSLTGRTIGGQ-------VSRITKQAFF--- 616
               .:.||......:|   ..:||:.||..:|||:..||||:...       |||:.|.|..
Frog   301 SGPCISTSKTSPLYSK---HSLNWSRGDHYIEVVDGSTGRTVDCSSTLGHFPVSRLCKAAMLKYY 362

  Fly   617 ----VKYGFLMANLPGILVRKVTTDYGQTKANVKDYQIAKLELFSAFKREDLGSWLKK 670
                ::||.|...:          .|.|:|.....||..|....|.|.....|.|.:|
Frog   363 WGLQIEYGKLHERI----------SYIQSKIFSDQYQRVKSLFHSHFCARTQGLWPRK 410

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Adar	NP_001368969.1	DSRM_STRBP_RED-like_rpt1	105..167	CDD:380694
		DSRM_SF	213..>259	CDD:412133
		ADEAMc	306..677	CDD:214718	117/406 (29%)
adad2	NP_001072832.1	A_deamin	102..410	CDD:413428	105/352 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D947117at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920