Protein Alignment Adar and adarb1b

DIOPT Version :10

• Sequence 1: NP_001368969.1
• Gene: Adar / 31130
• FlyBaseID: FBgn0026086
• Length: 681
• Species: Drosophila melanogaster
• Sequence 2: XP_021334693.1
• Gene: adarb1b / 558759
• ZFINID: ZDB-GENE-030219-15
• Length: 750
• Species: Danio rerio
• Alignment Length: 669
• Identity: 303/669 - (45%)
• Similarity: 406/669 - (60%)
• Gaps: 76/669 - (11%)

  Fly    73 GYNRKLPQKRGYEMPKYSD--PKKKMCKERIPQPKNTVAMLNELRHGLIYKLESQTGPVHAPLFT 135
            |..||.|.:.|.....:|.  |||:........|||.:..|||::.||.|||.|||||||||:|.
Zfish    94 GGGRKRPLEEGNNGHSHSKFRPKKRKKTPGPVLPKNALMQLNEIKPGLQYKLLSQTGPVHAPVFV 158

  Fly   136 ISVEVDGQKYLGQGRSKKVARIEAAATALRSFIQFKD--------GAVLSPLKPAGNLDFTSDEH 192
            ::|||:||.:.|.|.:||.|::.||..|||||:||.:        |..|:.     |.|||||:.
Zfish   159 MTVEVNGQLFEGSGPTKKKAKLNAAEKALRSFVQFPNASEAHLAMGRTLTV-----NTDFTSDQA 218

  Fly   193 LENDV--------------------SKSAITVDGQKKVPD------------------------K 213
            ...|:                    ...::...|:..||.                        |
Zfish   219 DFPDMLFNGFETPAPPEETFFLGSNGNGSLNPLGEYPVPQAAGTNSLVQAPLPPPSSFASSASGK 283

  Fly   214 GPVMLLYELFNDVNFECINIDGAQNNCRFKMTVTINEKKFDGTGPSKKTAKNAAAKAALASLCNI 278
            .|||:|.||...:.:|.::..|..:...|.|:||::.:.|:|:|.:||.||..||:|||:||.|
Zfish   284 NPVMILNELRPGLKYEFVSESGESHAKNFVMSVTVDSQMFEGSGRNKKLAKARAAQAALSSLFN- 347

  Fly   279 SYSPMVVPQKNVPLPIDDKSSSMELPQIHADTIGRLVLEKFMEVIKG-QEAYSRRKVLAGIVMTE 342
                |.:.|.....||..:...:.|||:.||.:.|||::||.|:... ...::|||||||:|||.
Zfish   348 ----MQLDQTPSRQPIPREGLQLHLPQVLADAVSRLVVDKFSELTDNFTSPHARRKVLAGVVMTT 408

  Fly   343 NMNFCEAKVISVSTGTKCVSGEHMSVNGAVLNDSHAEIVSRRCLLKYLYAQLD--LQCNQATAYQ 405
            ..:..:|:||.|||||||::||:||..|..|||.||||::||.|::|||.||:  |..|:....:
Zfish   409 GTDVKDAQVICVSTGTKCINGEYMSDRGLALNDCHAEIIARRSLIRYLYMQLEHFLSNNKEEHQK 473

  Fly   406 SIFVRNTDGQYPYKLKSGVHFHLYINTAPCGDARIFSPHE---NDTGVDKHPNRKARGQLRTKIE 467
            |||::..  :..|:||..|.|||||:|:||||||||||||   .|.| |:|||||||||||||||
Zfish   474 SIFMQCE--KRGYRLKDSVQFHLYISTSPCGDARIFSPHEAGVEDQG-DRHPNRKARGQLRTKIE 535

  Fly   468 SGEGTIPVKSSDGIQTWDGVLQGQRLLTMSCSDKIARWNIVGIQGSLLSSIIEPVYLHSIVLGSL 532
            ||||||||:||:.||||||||||:|||||||||||||||:|||||||:|...||:|..||:||||
Zfish   536 SGEGTIPVRSSNTIQTWDGVLQGERLLTMSCSDKIARWNVVGIQGSLMSYFSEPIYFSSIILGSL 600

  Fly   533 LHPEHMYRAVCGRIEKSIQGLPPPYHLNKPRLALVTSAEPRNQAKAPNFGINWTIGDTELEVVNS 597
            .|.:|:.||:..|| ..|:.||..:.||:|.|:.:::||.|...|||||.:|||:||..|||:|:
Zfish   601 YHADHLSRAMYQRI-ADIEDLPQQFSLNRPLLSGISNAEARQPGKAPNFSVNWTVGDQALEVINA 664

  Fly   598 LTGRTIGGQVSRITKQAFFVKYGFLMANLPGILVRKV--TTDYGQTKANVKDYQIAKLELFSAFK 660
            .||:...|:.||:.|.|.:.::..|.:.|...|..||  .:.|.:.|....:|..||..|..||.
Zfish   665 TTGKDDMGRASRLCKHALYSRWVRLHSKLSPTLRIKVPKPSSYHEAKQAAVEYHTAKQTLIKAFH 729

  Fly   661 REDLGSWLKKPIEQDEFGL 679
            :..||:|:|||||||:|.|
Zfish   730 KAGLGAWVKKPIEQDQFSL 748

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Adar	NP_001368969.1	DSRM_STRBP_RED-like_rpt1	105..167	CDD:380694	35/61 (57%)
		DSRM_SF	213..>259	CDD:444671	16/45 (36%)
		ADEAMc	306..677	CDD:214718	205/378 (54%)
adarb1b	XP_021334693.1	DSRM_RED1_rpt1	123..194	CDD:380724	39/70 (56%)
		DSRM_RED1_rpt2	282..350	CDD:380727	29/72 (40%)
		ADEAMc	371..747	CDD:214718	205/379 (54%)