DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Adar and Ilf3

DIOPT Version :9

Sequence 1:	NP_001368969.1	Gene:	Adar / 31130	FlyBaseID:	FBgn0026086	Length:	681	Species:	Drosophila melanogaster
Sequence 2:	XP_011240705.1	Gene:	Ilf3 / 16201	MGIID:	1339973	Length:	916	Species:	Mus musculus

Alignment Length:	335	Identity:	100/335 - (29%)
Similarity:	144/335 - (42%)	Gaps:	63/335 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 GRACYKSCHHAMRVARSSFGY----QRQQFYAASSYAGKRSRF-FVKRRFTFPSLPGNPVSAPSD 68
            |...|..|.   :.|..:.|:    ||:....::.:|.:.:.| .:.:......||......|.:
Mouse   306 GSGIYDPCE---KEATDAIGHLDRQQREDITQSAQHALRLAAFGQLHKVLGMDPLPSKMPKKPKN 367

  Fly    69 INMNGYNRKLPQKRGYEMPKYSDP-------------KKKMCKER----IPQPKNTVAMLNELRH 116
            .|...|..::|....|.:.....|             |||:.|:.    .||..|.:..||:|:.
Mouse   368 ENPVDYTVQIPPSTTYAITPMKRPMEEDGEEKSPSKKKKKIQKKEEKADPPQAMNALMRLNQLKP 432

  Fly   117 GLIYKLESQTGPVHAPLFTISVEVDGQKYLGQGRSKKVARIEAAATAL-----------RSFIQF 170
            ||.|||.|||||||||:||:||||||..:...|.|||.|::..|...|           |...:.
Mouse   433 GLQYKLISQTGPVHAPIFTMSVEVDGSNFEASGPSKKTAKLHVAVKVLQDMGLPTGAEGRDSSKG 497

  Fly   171 KDGAVLSPLKPA-------------GNLDFTSDEHLENDVSKSAITVDGQKKVPDKGPVMLLYEL 222
            :|.|..|..|||             .:..|.||...|..   ..:|..|      |.|||.|.|.
Mouse   498 EDSAEESDGKPAIVAPPPVVEAVSNPSSVFPSDATTEQG---PILTKHG------KNPVMELNEK 553

  Fly   223 FNDVNFECINIDGAQNNCRFKMTVTINEKKFDGTGPSKKTAKNAAAKAALASLCNISYSPMVV-- 285
            ...:.:|.|:..|..::.||.|.|.::.:||.|.|.:||.||..||.|||..|  ...:|:.:
Mouse   554 RRGLKYELISETGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAYAALAALEKL--FPDTPLALEA 616

  Fly   286 -PQKNVPLPI 294
             .:|..|:|:
Mouse   617 NKKKRTPVPV 626

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Adar	NP_001368969.1	DSRM_STRBP_RED-like_rpt1	105..167	CDD:380694	34/72 (47%)
		DSRM_SF	213..>259	CDD:412133	17/45 (38%)
		ADEAMc	306..677	CDD:214718
Ilf3	XP_011240705.1	DZF	106..360	CDD:128842	11/56 (20%)
		DSRM_ILF3_rpt1	416..488	CDD:380739	35/71 (49%)
		DSRM_ILF3_rpt2	538..609	CDD:380741	29/78 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	62	1.000	Domainoid score	I10264
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000