Protein Alignment Adar and ADAD2

DIOPT Version :9

• Sequence 1: NP_001368969.1
• Gene: Adar / 31130
• FlyBaseID: FBgn0026086
• Length: 681
• Species: Drosophila melanogaster
• Sequence 2: NP_631913.3
• Gene: ADAD2 / 161931
• HGNCID: 30714
• Length: 665
• Species: Homo sapiens
• Alignment Length: 466
• Identity: 134/466 - (28%)
• Similarity: 206/466 - (44%)
• Gaps: 85/466 - (18%)

  Fly   255 GTGPSKKTAKNAAAKAALASLCNISYSPMVVPQ-----KNVPL-PIDDKSSSMELPQIHADTIGR 313
            ||..||..||.   :|||::||.|. |.:..|:     ...|| |:     |:|....|......
Human   231 GTANSKTEAKQ---QAALSALCYIR-SQLENPESPQTSSRPPLAPL-----SVENILTHEQRCAA 286

  Fly   314 LVLEKFMEVIKGQEAY-SRRKVLAGIVMTE----NMNFCEA------------KVISVSTGTKCV 361
            ||...|..::..:..| :.:..:||:::..    :...|..            |::::.||:.|.
Human   287 LVSAGFDLLLDERSPYWACKGTVAGVILERGWAVSAPSCTEIPRARGHVKEIYKLVALGTGSSCC 351

  Fly   362 SGEHMSVNGAVLNDSHAEIVSRRCLLKYLYAQLDL--QCNQATAYQSIFVRNTDGQYPYKLKSGV 424
            :| .:..:|..|:|.|..:::||.||::|:.||.|  |.......||:.........|:.||..|
Human   352 AG-WLEFSGQQLHDCHGLVIARRALLRFLFRQLLLATQGGPKGKEQSVLAPQPGPGPPFTLKPRV 415

  Fly   425 HFHLYINTAPCGDAR-IFSPHENDTGVDKHPNRKAR----GQLRTKIESGEGTIPV--KSSDGIQ 482
            ..||||:..|.|.|| |:.|..::.|:...|..:.:    |||:          ||  .:.....
Human   416 FLHLYISNTPKGAARDIYLPPTSEGGLPHSPPMRLQAHVLGQLK----------PVCYVAPSLCD 470

  Fly   483 TWDGVLQGQRLLTMSCSDKIARWNIVGIQGSLLSSIIEPVYLHSIVLGSLLH-PEHMYRAVCGR- 545
            |..|.|        |.|||:|||.::|:.|:||:.::.|:|..|::|....| |..:.||:..|
Human   471 THVGCL--------SASDKLARWAVLGLGGALLAHLVSPLYSTSLILADSCHDPPTLSRAIHTRP 527

  Fly   546 IEKSIQG--LPPPYHLNKPRLALVTSAEPRNQAKAP------NFGINWTIGDTELEVVNSLTGRT 602
            ...|:.|  |||||    .|.||...|.|......|      ...:||::||..:|||:..|||.
Human   528 CLDSVLGPCLPPPY----VRTALHLFAGPPVAPSEPTPDTCRGLSLNWSLGDPGIEVVDVATGRV 588

  Fly   603 IG----GQVSRITKQAFFVKY--GFLMANLPGILVRKVTTDYGQTKANVKDYQIAKLELFSAFKR 661
            ..    |..||:.|.:|...:  .......|.:|..|.   |...||.  .||.|:.:|.....:
Human   589 KANAALGPPSRLCKASFLRAFHQAARAVGKPYLLALKT---YEAAKAG--PYQEARRQLSLLLDQ 648

  Fly   662 EDLGSWLKKPI 672
            :.||:|..||:
Human   649 QGLGAWPSKPL 659

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Adar	NP_001368969.1	DSRM_STRBP_RED-like_rpt1	105..167	CDD:380694
		DSRM_SF	213..>259	CDD:412133	2/3 (67%)
		ADEAMc	306..677	CDD:214718	115/409 (28%)
ADAD2	NP_631913.3	dsrm	<217..251	CDD:278464	11/22 (50%)
		A_deamin	343..658	CDD:280326	104/342 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165158123
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2777
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D947117at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.750