Protein Alignment Adar and adad1

DIOPT Version :10

• Sequence 1: NP_001368969.1
• Gene: Adar / 31130
• FlyBaseID: FBgn0026086
• Length: 681
• Species: Drosophila melanogaster
• Sequence 2: NP_001116945.1
• Gene: adad1 / 100144718
• XenbaseID: XB-GENE-493326
• Length: 584
• Species: Xenopus tropicalis
• Alignment Length: 685
• Identity: 174/685 - (25%)
• Similarity: 282/685 - (41%)
• Gaps: 183/685 - (26%)

  Fly    70 NMNGYNRKLPQKRGYEMPKYSDPKKKMCKERIPQPKNTVAMLNELRHGLIY--------KLESQT 126
            |:|...|.       .:|.::    :|.|:.:|.....|.:.:.:.....|        |:...|
 Frog     4 NVNWIQRS-------SVPSFA----QMLKKNLPAQAPAVNLSSTVSTCCPYVEPDCGTAKVTQIT 57

  Fly   127 GPVHAPLFTISVEVDGQKYLGQGRSKKVARIEAAATAL------RSF-IQFKDGAVLSPLKPAGN 184
            |....|..                ||.|  :.|:.::|      :.| ::::.|    .|.|...
 Frog    58 GNFREPFL----------------SKMV--VPASLSSLPPRKVTKEFVVKYRRG----DLNPVSA 100

  Fly   185 L-DFTSDEHLENDVSKSAITVDGQKKVPDKGPVMLLYELFNDVNFECINIDGAQNNCRFKMTVTI 248
            | .|...:.:|.|:.::..|          |.|...|..|      |..|||.:    :|
 Frog   101 LYQFAQMQRMEIDLKETVTT----------GNVFGAYFAF------CAVIDGIE----YK----- 140

  Fly   249 NEKKFDGTGPSKKTAKNAAAKAALASL---------------CNISYSPMVVPQKNVPLPIDDKS 298
                 .|.|.:||.||..||:.||..|               .||..:|.::|.|.   .:..::
 Frog   141 -----TGMGQNKKEAKANAAQLALDELLLHEDSELTATHPESLNIMENPPLIPLKP---KVTTET 197

  Fly   299 SSMELPQ------IHADTIGRLVLEKFMEVI-KGQEAYSRRKVLAGIVMTE-NMNFCEAKVISVS 355
            |::...:      || :.|..::.|.|..:| |..|..|....||..|:.: ..|:   :|::|.
 Frog   198 STISRARTDKRTFIH-EKISSIIKETFTNLISKYPEYESCGSSLAAFVIEKGGQNW---EVVAVG 258

  Fly   356 TGTKCVSGEHMSVNGAVLNDSHAEIVSRRCLLKYLYAQLDL--QCNQATAYQSIFVRNTDGQYPY 418
            || :...|:.:..:|.||:||||.:|:||.||:|.|.||.|  ..|.....:|||........ .
 Frog   259 TG-EFNYGQSLQSDGRVLHDSHAIVVARRSLLRYFYRQLLLFYSGNNGMMDKSIFCTEPATNL-L 321

  Fly   419 KLKSGVHFHLYINTAPCGDAR-----IFSPHENDTGVDKHPNRKARGQLRTKIESGEGTIPVKSS 478
            .||...:..||:|..|.|.|:     ..|||    .:..|   :|..:|...:......||....
 Frog   322 ALKPNFNIFLYMNQLPKGAAQTNPQLCLSPH----SLSAH---EANDKLSLHVSVEGKNIPAAYY 379

  Fly   479 DGIQTWDGVLQGQRLLTMSCSDKIARWNIVGIQGSLLSSIIEPVYLHSIVLGSLLHPEHMYRAVC 543
            .|...       ..|.:||.:||:.||.::|:||:|||..|:|||:.:|::|:         |.|
 Frog   380 SGEIV-------HNLYSMSSTDKLTRWEVLGVQGALLSVFIQPVYISTIIVGN---------AAC 428

  Fly   544 G-----------RIEKSIQG-LPPPYHLNKPRLALV-----TSAEPRNQAKAPNFGINWTIGDTE 591
            .           ||:.::.. ||..|.:|:|.:::|     |:.:|.|:    :..:||:.||..
 Frog   429 SDTRGLEIAVKQRIDDALTSKLPMFYLVNRPYISIVSSTHQTNMDPVNR----SLSLNWSQGDAC 489

  Fly   592 LEVVNSLTGRTI------GGQ--VSRITKQAFFVKYGFLM------ANLPGILVRKVTTDYGQTK 642
            :|||:::.|:|:      .|.  .||:.|.|...::..::      |..|.:       .|.:.|
 Frog   490 VEVVDAVRGKTVERSPFKSGSCLASRLCKAAMLCRFNLVVKESKREAIAPDL-------SYHEAK 547

  Fly   643 ANVKDYQIAKLELFSAFKREDLGSWLKKPIEQDEF 677
            .....||.||..|.:.||::..|||:.||...|||
 Frog   548 HLAGPYQEAKCLLKAYFKQQGFGSWIVKPPIIDEF 582

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Adar	NP_001368969.1	DSRM_STRBP_RED-like_rpt1	105..167	CDD:380694	11/75 (15%)
		DSRM_SF	213..>259	CDD:444671	11/45 (24%)
		ADEAMc	306..677	CDD:214718	119/410 (29%)
adad1	NP_001116945.1	DSRM_ADAD1	96..163	CDD:380734	25/96 (26%)
		A_deamin	256..576	CDD:460458	102/355 (29%)