DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Scgdelta and sgcd

DIOPT Version :9

Sequence 1:	NP_001162639.2	Gene:	Scgdelta / 31129	FlyBaseID:	FBgn0025391	Length:	404	Species:	Drosophila melanogaster
Sequence 2:	NP_001001816.2	Gene:	sgcd / 324961	ZFINID:	ZDB-GENE-030131-3684	Length:	292	Species:	Danio rerio

Alignment Length:	268	Identity:	112/268 - (41%)
Similarity:	161/268 - (60%)	Gaps:	11/268 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly   134 LGLIGWRKKCLYTLLLLLMLLIITNLVLTLWILKVMEFSTEGMGQLKIVPGGIQLSGQAIIMDML 198
            :|:.||||:|||..:||||:||:.||.||:||||||.|:.:|||.|:|...|::|.|.:..:..|
Zfish    27 VGIYGWRKRCLYFFVLLLMILIVVNLALTIWILKVMNFTIDGMGHLRITERGLKLEGDSEFLQPL 91

  Fly   199 RASTIRSRHGQPISIESSRNFSINTRDPNGMIENHLFLGHDKFECLSAGFRINDTNGRSLFSVNR 263
            .|..|:||.|.|:.::||:|.|:|..:....:.:.|..|............:..::|:.|||.:.
Zfish    92 YAKEIQSRPGSPLFLQSSKNVSVNILNEKKQLVSQLVAGSHGVHARGKMLEVKSSSGKLLFSADD 156

  Fly   264 DEVTIGAHALRIDGEGGAVFRESVQTPHVRAEPGRELRLESPTRQLEMTAAKDINLQSRAGGIEV 328
            .||.:||..||:.|..||||..||:||||||||.:|||||||||.|.|.|.|.:.:::.||..:.
Zfish   157 HEVVVGAERLRVMGAEGAVFSNSVETPHVRAEPFKELRLESPTRSLYMEAPKGVKIEADAGDFQA 221

  Fly   329 VALEDVKFRALDGSLRLESSKILMPNLRTAQPPILGTAQSRDHMHRVFQLCACSNGKLFLAAPHS 393
            ....|::..:.||.:.|::|||.:|.|...:....|..|:      ||::|.|.||||||:.
Zfish   222 TCRSDLRLESKDGEISLDASKIKLPRLPEGKASTSGPRQT------VFEVCVCPNGKLFLSQ--- 277

  Fly   394 ICAGDDST 401
              ||..||
Zfish   278 --AGTGST 283

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Scgdelta	NP_001162639.2	Sarcoglycan_1	160..393	CDD:282624	92/232 (40%)
sgcd	NP_001001816.2	Sarcoglycan_1	26..279	CDD:309778	108/262 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170577409
Domainoid	1	1.000	215	1.000	Domainoid score	I2655
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H285
Inparanoid	1	1.050	215	1.000	Inparanoid score	I3593
OMA	1	1.010	-	-		QHG52294
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001824
OrthoInspector	1	1.000	-	-		otm25701
orthoMCL	1	0.900	-	-		OOG6_106318
Panther	1	1.100	-	-	LDO	PTHR12939
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1185
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	12	11.900