DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Scgdelta and SGCZ

DIOPT Version :9

Sequence 1:	NP_001162639.2	Gene:	Scgdelta / 31129	FlyBaseID:	FBgn0025391	Length:	404	Species:	Drosophila melanogaster
Sequence 2:	NP_631906.2	Gene:	SGCZ / 137868	HGNCID:	14075	Length:	312	Species:	Homo sapiens

Alignment Length:	278	Identity:	107/278 - (38%)
Similarity:	162/278 - (58%)	Gaps:	15/278 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly   134 LGLIGWRKKCLYTLLLLLMLLIITNLVLTLWILKVMEFSTEGMGQLKIVPGGIQLSGQAIIMDML 198
            :|:.||||:|||..:|||::.:|.||.:|:||||||.|:.:|||.|::...||:|.|.:..:..|
Human    39 VGIYGWRKRCLYFFVLLLLVTMIVNLAMTIWILKVMNFTVDGMGNLRVTKKGIRLEGISEFLLPL 103

  Fly   199 RASTIRSRHGQPISIESSRNFSINTRDPNGMIENHLFLGHDKFECLSAGFRIN-DTNGRSLFSVN 262
            ....|.||...|:.::|.||.::|.|:..|.:...|.:|.|..|.....|.:. ..:||.|||.:
Human   104 YVKEIHSRKDSPLVLQSDRNVTVNARNHMGQLTGQLTIGADAVEAQCKRFEVRASEDGRVLFSAD 168

  Fly   263 RDEVTIGAHALRIDGEGGAVFRESVQTPHVRAEPGRELRLESPTRQLEMTAAKDINLQSRAGGIE 327
            .||:||||..|::.|..||||..||:|||:||||.::||||||||.|.|.|.:.:.:.:.||..:
Human   169 EDEITIGAEKLKVTGTEGAVFGHSVETPHIRAEPSQDLRLESPTRSLIMEAPRGVQVSAAAGDFK 233

  Fly   328 VVALEDVKFRALDGSLRLESSKILMPNLRT-----AQPPILGTAQSRDHMHRVFQLCACSNGKLF 387
            ....:::..::.:|.:.|.:..|.:.||.|     :.|....:.|:      |::||.|.||||:
Human   234 ATCRKELHLQSTEGEIFLNAETIKLGNLPTGSFSSSSPSSSSSRQT------VYELCVCPNGKLY 292

  Fly   388 L--AAPHSICAGDDSTVC 403
            |  |...|.|. ..|.:|
Human   293 LSPAGVGSTCQ-SSSNIC 309

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Scgdelta	NP_001162639.2	Sarcoglycan_1	160..393	CDD:282624	89/240 (37%)
SGCZ	NP_631906.2	Sarcoglycan_1	38..297	CDD:398454	102/263 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165144334
Domainoid	1	1.000	208	1.000	Domainoid score	I2861
eggNOG	1	0.900	-	-		E1_KOG3950
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	213	1.000	Inparanoid score	I3641
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG52294
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001824
OrthoInspector	1	1.000	-	-		otm40990
orthoMCL	1	0.900	-	-		OOG6_106318
Panther	1	1.100	-	-	O	PTHR12939
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3754
SonicParanoid	1	1.000	-	-		X1185
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	14	13.790