DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3795 and Prss53

DIOPT Version :9

Sequence 1:	NP_001284790.1	Gene:	CG3795 / 31128	FlyBaseID:	FBgn0025378	Length:	305	Species:	Drosophila melanogaster
Sequence 2:	XP_006230384.1	Gene:	Prss53 / 499270	RGDID:	1566127	Length:	591	Species:	Rattus norvegicus

Alignment Length:	287	Identity:	67/287 - (23%)
Similarity:	102/287 - (35%)	Gaps:	94/287 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    77 HFCAGTIFSERAILTAAHCMFSNRRKLKAKKLMVVAGTPRRLLKSSTTQIIEAEEL----LPHPK 137
            |.|:|::.::..:|||||| |......:.....||.|:.::...|.     .|||:    |..||
  Rat    60 HICSGSLVADTWVLTAAHC-FEKMATAELSSWSVVLGSLKQEGLSP-----GAEEVGVAALQLPK 118

  Fly   138 YKKGKSQKYDIGLI-----LLEADLSLGDAVAKIPLYNKVPVAGAPCSIVGW------------- 184
            .....||..|:.|:     ::...|.|.......|.       ||.|...||
  Rat   119 AYNHYSQGSDLALLQLTHPIVHTTLCLPQPTHHFPF-------GASCWATGWDQNTSDGKYCPRH 176

  Fly   185 -------GTVI---------------QFGPLPDEAINGDMQI----LPDTFC------EKLL-GW 216
                   |:|:               ...|||......::::    .|...|      ::|| ..
  Rat   177 KSRESQTGSVLTVLALCSHCVSELDSTLSPLPVSRTLRNLRLRLISRPTCNCLYNRLHQRLLANP 241

  Fly   217 SNAGMLCANDKHDSDVDSCQGDSGGPLICDN-----MVTGIVSFGMGCGEPDSAGIYTDVYHFRD 276
            :.:||||...:.... ..||||||||::|..     :..||:||...|.:.|:..:.||:.....
  Rat   242 ARSGMLCGGAQPGVQ-GPCQGDSGGPVMCREPDGHWVQVGIISFTSNCAQEDTPVLLTDMAAHSS 305

  Fly   277 WI--------------------TENSC 283
            |:                    .||||
  Rat   306 WLQAHVDRAAFLVQDPGVVKMSDENSC 332

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3795	NP_001284790.1	Tryp_SPc	60..281	CDD:238113	63/283 (22%)
CG3795	NP_001284790.1	Tryp_SPc	60..278	CDD:214473	62/260 (24%)
Prss53	XP_006230384.1	Tryp_SPc	45..310	CDD:238113	63/263 (24%)
Prss53	XP_006230384.1	Tryp_SPc	341..561	CDD:238113
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24276
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100