DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3795 and PRSS55

DIOPT Version :9

Sequence 1:	NP_001284790.1	Gene:	CG3795 / 31128	FlyBaseID:	FBgn0025378	Length:	305	Species:	Drosophila melanogaster
Sequence 2:	NP_940866.2	Gene:	PRSS55 / 203074	HGNCID:	30824	Length:	352	Species:	Homo sapiens

Alignment Length:	250	Identity:	79/250 - (31%)
Similarity:	123/250 - (49%)	Gaps:	39/250 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    46 VTGGYRPDTNDLVKYTVSLR-MGKPKKFFGDNHFCAGTIFSERAILTAAHCMFSNRRKLKAKKLM 109
            :|||...:..:. .:.||:: ..:|        ||.|:|.::..|||||||::|  .:|..::|.
Human    68 ITGGMEAEVGEF-PWQVSIQARSEP--------FCGGSILNKWWILTAAHCLYS--EELFPEELS 121

  Fly   110 VVAGTPRRLLKSSTTQIIEAEELLPHPKYKKGKSQKYDIGLILLEADLSLGDAVAKIPLYNKVPV 174
            ||.||  ..|.|.:.:|.|...::.|..:|:..... ||.|:||.:.:.|.|  .|:|:.  :|.
Human   122 VVLGT--NDLTSPSMEIKEVASIILHKDFKRANMDN-DIALLLLASPIKLDD--LKVPIC--LPT 179

  Fly   175 AGAP-----CSIVGWGTVIQFGPLPDEAINGDMQILPDTF-----CEKLLGWSNAGMLCANDKHD 229
            ...|     |.:.|||   |.......::..|:...|...     |.|:.......||||..|::
Human   180 QPGPATWRECWVAGWG---QTNAADKNSVKTDLMKAPMVIMDWEECSKMFPKLTKNMLCAGYKNE 241

  Fly   230 SDVDSCQGDSGGPLICDN------MVTGIVSFGMGCGEPDSAGIYTDVYHFRDWI 278
            | .|:|:|||||||:|..      ...||:|:|..|||.::.||||.:.::..||
Human   242 S-YDACKGDSGGPLVCTPEPGEKWYQVGIISWGKSCGEKNTPGIYTSLVNYNLWI 295

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3795	NP_001284790.1	Tryp_SPc	60..281	CDD:238113	75/235 (32%)
CG3795	NP_001284790.1	Tryp_SPc	60..278	CDD:214473	74/234 (32%)
PRSS55	NP_940866.2	Tryp_SPc	67..295	CDD:214473	77/248 (31%)
		Tryp_SPc	68..298	CDD:238113	78/249 (31%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	308..330
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910