Protein Alignment b6 and PTX3

DIOPT Version :10

• Sequence 1: NP_477365.1
• Gene: b6 / 31124
• FlyBaseID: FBgn0024897
• Length: 558
• Species: Drosophila melanogaster
• Sequence 2: NP_002843.2
• Gene: PTX3 / 5806
• HGNCID: 9692
• Length: 381
• Species: Homo sapiens
• Alignment Length: 292
• Identity: 62/292 - (21%)
• Similarity: 107/292 - (36%)
• Gaps: 73/292 - (25%)

  Fly    36 GTAAYSL-KQSHPGAASSSHEISTSFSQFGGDKETTEVEDELLLG------RAAIVNGVDSSAAV 93
            |..|.|| :...|||.:              :...|...||||..      |.|.:.|.::....
Human    93 GRLAESLARPCAPGAPA--------------EARLTSALDELLQATRDAGRRLARMEGAEAQRPE 143

  Fly    94 SHPISFADHLED----QYESYSIEDEAPKE--------PLAFPRSPVYGSDRCSVKKFAFNQDGE 146
            ....:.|..||:    :.:.::::..|.:.        .:.||..        |.|.|     |.
Human   144 EAGRALAAVLEELRQTRADLHAVQGWAARSWLPAGCETAILFPMR--------SKKIF-----GS 195

  Fly   147 VEYGNPMPELDQFTICFWMRFTNHSGDHVLLTYEAGKEPREVQ--------IWVANAQNSSFLSM 203
            |....|| .|:.|:.|.|::.|:.....:|.:|...:.|.|:|        ::|...:.:..::.
Human   196 VHPVRPM-RLESFSACIWVKATDVLNKTILFSYGTKRNPYEIQLYLSYQSIVFVVGGEENKLVAE 259

  Fly   204 AIKGQQMYRLNYPLKMRQWHHMCSSWNGKTGEWQAWLKAERIGRGFHNSLVGHKIPANGKLRSG- 267
            |:           :.:.:|.|:|.:||.:.|....|:..| :.........||.:|..|.|:.|
Human   260 AM-----------VSLGRWTHLCGTWNSEEGLTSLWVNGE-LAATTVEMATGHIVPEGGILQIGQ 312

  Fly   268 ---GSSVTGEVSHGLHF--EMTLVQVYRVALS 294
               |..|.|.....|.|  .:|...::...||
Human   313 EKNGCCVGGGFDETLAFSGRLTGFNIWDSVLS 344

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
b6	NP_477365.1	LamG	134..>264	CDD:473984	31/137 (23%)
PTX3	NP_002843.2	CHAD	69..>165	CDD:444338	18/85 (21%)
		PTX	175..381	CDD:128463	43/196 (22%)