Protein Alignment CG32809 and si:ch211-278a6.1

DIOPT Version :9

• Sequence 1: NP_001245466.1
• Gene: CG32809 / 31121
• FlyBaseID: FBgn0023531
• Length: 1264
• Species: Drosophila melanogaster
• Sequence 2: XP_021330368.1
• Gene: si:ch211-278a6.1 / 565863
• ZFINID: ZDB-GENE-060503-699
• Length: 1611
• Species: Danio rerio
• Alignment Length: 1470
• Identity: 319/1470 - (21%)
• Similarity: 505/1470 - (34%)
• Gaps: 514/1470 - (34%)

  Fly    45 GRLPSN--EQGGDERRRAMRRDD---PRRH-TLGGDM-------LVYGSQHPHA----------- 85
            |..||.  |:||.   ..:..||   ||.: |||.:.       ||:.|:|.|.
Zfish     2 GNAPSQDPERGGG---HMISTDDLEYPREYRTLGNNTRRFSNVGLVHTSEHRHTVIAAQSLETLT 63

  Fly    86 --HQMAPQQQRAMDLE----------------------MSTRAQKNKKNQPMRGY---------- 116
              |:...:::|.:.::                      |...|:::.:.|....|
Zfish    64 NLHKADMERKRDVFMDHLKNKYPPQHSLPPSPSPSHGSMRGSAERSAREQQQPNYWSFKSRSPRH 128

  Fly   117 APVNQGPLFDDDPGI----------MSEVETASTGFRRGGKQRSSLPVVRTPSKTLERPLGLVFL 171
            :...|..|.|....:          |||.: ...||.|..:.|.|||:.|:.|:...|..|::||
Zfish   129 SQSTQSGLADQASKLSFASAESLETMSEAD-MPLGFNRMNRFRQSLPLSRSASQNKLRSPGVLFL 192

  Fly   172 QYRSETKRALLPNEITSIDTVRALFVRSFPRQLTMSYLEGPNVKIYIHDASKDMFYELEDVRSHL 236
            |:..||:|..:.:|:.|::|:.||.|..||::||...|:.||..|.|.|.::::|||||||
Zfish   193 QFGDETRRVHITHELNSLETLHALIVHMFPQKLTAGMLKSPNTAILIKDEARNVFYELEDV---- 253

  Fly   237 REIRDRSVLRLFESTEVAA---------------------------------------------- 255
            |:|:|||:::::....:.|
Zfish   254 RDIQDRSIIKIYRKEPIYASYPAAHLANGDLRREMVYTSRDSSPTRRLNTLPSSSTSHSSGSPSR 318

  Fly   256 ---------PPQILPGGPGIPQPL-PQAQANWDQDQSYFSEPEFDSDYKHQHIHKSKIGKQPAPY 310
                     ||..  .|||.|.|. ||..                   :|.| |.|....|....
Zfish   319 SRLSYSGGRPPSF--AGPGHPHPQGPQHS-------------------QHSH-HPSPSHGQGQGL 361

  Fly   311 YVGSSQTLPR--------------------GMYSS-----ERNKVSM-------------GAPVK 337
            ...||..|.|                    |:|:.     ...::|:             |.||.
Zfish   362 TPSSSAILERRDVKPDEEMSGKNMVLLKNEGLYADPYSLMHEGRLSIASTQSLATIADPFGFPVS 426

  Fly   338 PLRSLNPRGSMEPLFPYT--------PDQLY----------------------------SIP--- 363
              ..|..|||:..|..|:        .|.||                            .||
Zfish   427 --GGLYRRGSVRSLSTYSAAALQNDLEDSLYKPGGSLYSDAYSSSTLGMGFRLPPSSPQKIPDVQ 489

  Fly   364 ----DGYTSSPERSSRGNYEEPYYSQYGTRGAVVAPIIDEEQS----------DGTMTEDQYALY 414
                |.:|.||.|.|      |..:.:....|..:..::..:|          ||:    :.|.:
Zfish   490 LRDRDSFTGSPSRGS------PVRTTFRKDSASSSVFVESPKSRPSSSSEPLGDGS----KGAGF 544

  Fly   415 GIKVGPGPNRLTHRGNQIYDPTRPEDLHRIRVEHMERQLANLTGLVQKALVNQNPQIAPLAVPTL 479
            |..:.         |.:|       |..|.|:|.||:|:|:||||||..|..         .|..
Zfish   545 GSPLS---------GGEI-------DSRRDRMEAMEKQIASLTGLVQSVLTR---------APDS 584

  Fly   480 DPNYLVVPSQMQANGSGDELYIREKAPKLGKNSCQKSVSFEKSVSFSDDIQGIPKSHNPLHAAET 544
            |....::...|.|....|:                 ...|.:...||.             :.:|
Zfish   585 DSTCGLLRLCMMAGCPPDQ-----------------GADFSRPFPFSS-------------SEKT 619

  Fly   545 KPTKPAIKSSTLPRTSSQERDRLKPPPP----PKPIVLAQTAHPNYRADIALAPEVYNHLRGLQK 605
            :.|...  |:|  .|...::..|.|..|    |.|......|....|..:.|      ||..||:
Zfish   620 ESTSEG--SAT--GTGRLKKKALTPSAPLALMPPPSSGGSQASTVSRLQMQL------HLHDLQQ 674

  Fly   606 KAKDLRMEVRTLRRLSQAQAVAVREDIKGTFMRIRATLLASSGSFWDHQGDQDATRISREEELYK 670
            .|.|||.::..||::......::|..:|.|...:...|             .||.| .:|:.|.:
Zfish   675 NATDLRKQLAQLRKMQLQNQDSIRSLLKRTETELSLRL-------------SDALR-KQEDPLQR 725

  Fly   671 QEVI----RLE---------KDLSDLEGSVENLRGEVINRRTRVNMTAVEDMALVLSRASKTVAE 722
            |.::    ||:         :.|.|||.|||.::.|:......|.:..:|:.:.:|.:..:|:.|
Zfish   726 QRLLVEEERLKYLNEEELIIQQLHDLEKSVEEIQKEISVNHRHVTVQELEEKSSMLRKLGETLTE 790

  Fly   723 LKLKFPSLSNGLRCILSNEMEKVVREEKFLKEEPDRLESALRRCKKLTGTLVTLKRLASVQEQRL 787
            ||.:||.|.:.:|.:|..|:|.|    |||||||.||::.|:|||.:|.||.||:|
Zfish   791 LKNQFPGLQSKMRVVLRVEVEAV----KFLKEEPHRLDALLKRCKSITDTLTTLRR--------- 842

  Fly   788 PPNEPTISEETPRSAD-ISAPDKPIPTPRMGSFALSGGLAPENALDALLDELK-------TFSKP 844
                 .::|...:|.| .|:|          |..|.||           ||.:       ..|.|
Zfish   843 -----QVNEGVWKSQDEFSSP----------SAKLGGG-----------DEYRKNTDFDIPTSPP 881

  Fly   845 IAQQQQQQQQQQQQQQQQHQH-QQLYEIRPEDS--------------------ASDESAQAAVQS 888
            ::..:...........|.|.| ...:..|.:||                    .|::::...|:.
Zfish   882 LSLNESSLANWSPHPGQGHGHSNSSHAQREKDSHGVMVGSLKTRGLEELGGRGGSEKASSVEVRL 946

  Fly   889 TVTTQISQARL----YTEASVN-VQQATTGSMVIAVASGTVSAQ----AQAQRGVLTHQQSQSQA 944
            .......:.|.    |:...:| :.:.|...::.|:.....:|:    ||.|........:|:|.
Zfish   947 AAERDWEEKRASLTQYSAQDINRLLEETQAELMKAIPDLDFAAKQIKPAQNQNQNQNQNPNQNQN 1011

  Fly   945 QLMVHTN------------------MGSLR-----RLHSYPSESDGELPGPPPTGPRASETSSST 986
            .....||                  .||.|     .:..|.:|...:.|.|||  ||.|..||
Zfish  1012 PSPSSTNATPEHRPNKPQHKLNSKDSGSRRGSDELTVARYRTEKPSKSPPPPP--PRRSFPSS-- 1072

  Fly   987 SLANGGSSSKPPVPERNAELI----------TKVGHKRIPPPPPPRTSSRSPLASPTSPNVPPNQ 1041
                      |.:..|:.|:|          ::....:.|.....|:.|.:|..:.|.|.:...:
Zfish  1073 ----------PGLTTRSGEIIIPGKSIKKSESEEAESQKPHVKLRRSISEAPRPASTPPTIAGGE 1127

  Fly  1042 ---------AAAATVNLIP-----NSNSN-----------ASANANANANSNATGNKGIVGETTS 1081
                     ||.....|.|     :.||:           .|:|..........|:..:.....|
Zfish  1128 REEADDEKLAAELEQQLTPSKSGFHENSSDLTQKPMIQHGVSSNPVPQIVLTECGSLPMSPSEDS 1192

  Fly  1082 VVSGDTSSGDNSSGNESGND-------HVQRQVALEMRHQELLKKQKMLQ-EQYQRLQQMSKLPS 1138
            ..:..:|.......|::|||       |:.|...|.:..|:|...||:.| :.....|:..:.|.
Zfish  1193 AENRPSSDDQTIKDNDTGNDIRVSYFSHIVRTPRLSLWKQDLTTSQKVPQIQDLDAAQRELQCPV 1257

  Fly  1139 VDVASSSSSSAQDIASGSNTLRKLGSETNIQQKIAALSLA 1178
            .||..|.....::.|. ...||:   |..:|:.:.|::.|
Zfish  1258 HDVTQSCLPLTRERAI-KQPLRR---EPRVQESLEAVTEA 1293

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32809	NP_001245466.1	AIP3	170..>247	CDD:281852	34/76 (45%)
si:ch211-278a6.1	XP_021330368.1	AIP3	191..>262	CDD:332043	34/74 (46%)
		SMC_N	<672..>846	CDD:330553	62/205 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170590887
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	225	1.000	Inparanoid score	I3477
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002249
OrthoInspector	1	1.000	-	-		otm25602
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR22741
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2349
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	8	8.040