Protein Alignment CG32809 and Srcin1

DIOPT Version :10

• Sequence 1: NP_001245466.1
• Gene: CG32809 / 31121
• FlyBaseID: FBgn0023531
• Length: 1264
• Species: Drosophila melanogaster
• Sequence 2: XP_017170155.1
• Gene: Srcin1 / 56013
• MGIID: 1933179
• Length: 1510
• Species: Mus musculus
• Alignment Length: 1196
• Identity: 280/1196 - (23%)
• Similarity: 438/1196 - (36%)
• Gaps: 383/1196 - (32%)

  Fly    11 SASSNQSVGGSSSSSSKKKRKGREGEDWQNEAKSGRLPSNEQGGDERRRAMR-RDDPRRHTLGGD 74
            :|.|.:::.|...:.:.:||     :.:.:..|| :.|       :...|:| :.|..|..:||.
Mouse   116 AAQSLEALSGLQKADADRKR-----DAFMDHLKS-KYP-------QHALALRGQQDRMREQVGGW 167

  Fly    75 ML------------VYGSQHPHAHQMAPQQQRAMDLEMSTRAQKNKKNQPMRGYAPVNQGPLFDD 127
            .:            ::|...|.......||......:  ||:.::            .||.
Mouse   168 TVDPVCLLSSLCSHLHGDSTPSGAGQPAQQPNYWSFK--TRSSRH------------TQGA---- 214

  Fly   128 DPGI-----------------MSEVETASTGFRRGGKQRSSLPVVRTPSKTLERPLGLVFLQYRS 175
            .||:                 |||.| ...||.|..:.|.|||:.|:.|:|..|..|::|||:..
Mouse   215 QPGLADQAAKLSYASAESLETMSEAE-LPLGFSRMNRFRQSLPLSRSASQTKLRSPGVLFLQFGE 278

  Fly   176 ETKRALLPNEITSIDTVRALFVRSFPRQLTMSYLEGPNVKIYIHDASKDMFYELEDVRSHLREIR 240
            ||:|..:.:|::|:||:.||....||::|||..|:.||..|.|.|.::::|||||||    |:|:
Mouse   279 ETRRVHITHEVSSLDTLHALIAHMFPQKLTMGMLKSPNTAILIKDEARNVFYELEDV----RDIQ 339

  Fly   241 DRSVLRLF--ESTEVAAPPQILPGG---------------------------------------- 263
            |||:::::  |....|.|...|..|
Mouse   340 DRSIIKIYRKEPLYAAFPGSHLTNGDLRVCLRAPKTLREMVYASRESSPTRRLNNLSPASHLASS 404

  Fly   264 ---PGIPQPLPQAQANWDQDQSYFS-----EPEFDSDYKHQHIHK-----SKIGKQPAPYYV--- 312
               ||:|..||....:....:|..|     .|.:.....|....:     :..|..|:|..:
Mouse   405 SPPPGLPSGLPSGLPSGSPSRSRLSYAGGRPPSYAGSPVHHAAERLGGAPTGQGVSPSPSAILER 469

  Fly   313 --------------GSSQTLPRGMYSS-----ERNKVSMGAPV-KPLR-----SLNPRGSMEPLF 352
                          |.......|:|:.     ...::|:.|.. .|..     .|..|||:..|.
Mouse   470 RDVKPDEDLAGKAGGMVLVKGEGLYADPYGLLHEGRLSLAAAAGDPFAYPGAGGLYKRGSVRSLS 534

  Fly   353 PYT--------PDQLYS-------IPDGY-----TSSPER----SSRGNYEEPYYSQYG---TRG 390
            .|:        .|.||.       ..|||     .|||::    |:......|.:|.|.   :||
Mouse   535 TYSAAALQSDLEDSLYKAGAGGPLYGDGYGFRLPPSSPQKLADVSAPSGGPPPPHSPYSGPPSRG 599

  Fly   391 AVVAPIIDEE---------------QSDGTMTEDQYALYGIKVGPGPNRLTHRGNQIYDPTRPED 440
            :.|.....::               :|.|:.:........:..|||...|...|    .|...:|
Mouse   600 SPVRQSFRKDSGSSSVFAESPGGKARSTGSASTAGAPPSELFPGPGERSLVGFG----PPVPAKD 660

  Fly   441 LH-RIRVEHMERQLANLTGLVQKALVNQNPQIAPLAVPTLDPNYLVVPSQMQANGSGDELYIREK 504
            .. |.|:|.||:|:|:||||||.||:..:           :|.   .||:.....:|   .....
Mouse   661 TETRERMEAMEKQIASLTGLVQSALLRGS-----------EPE---TPSEKVEGSNG---AATPS 708

  Fly   505 APKLGKNSCQKSVSFEKSVSFSDDIQGIPKSHNPLHAAETKPTKPAIKSSTLPRTSSQERDRLKP 569
            ||..|..|                                       |||.....|.
Mouse   709 APVCGSGS---------------------------------------KSSGATPVSG-------- 726

  Fly   570 PPPPKPIVLAQTAHPNYRADIALAPEVYNHLRGLQKKAKDLRMEVRTLRRLSQAQAVAVREDIKG 634
            ||||     :.::.|..:.......::..||||||..|.|||.:::.||:|......:||..:|.
Mouse   727 PPPP-----SASSTPAGQPTAVSRLQMQLHLRGLQNSASDLRGQLQQLRKLQLQNQESVRALLKR 786

  Fly   635 T----FMRIRATLLASSGSFWDHQGDQDATR-----ISREEELYKQEVIR-------LEKDLSDL 683
            |    .||:                 .:|.|     :.|:..|.::|.:|       :.:.|:||
Mouse   787 TEAELSMRV-----------------SEAARRQEDPLQRQRTLVEEERLRYLNDEELITQQLNDL 834

  Fly   684 EGSVENLRGEVINRRTRVNMTAVEDMALVLSRASKTVAELKLKFPSLSNGLRCILSNEMEKVVRE 748
            |.|||.::.:|.:....|....:|:.||||.:..:|:.|||..||.|.:.:|.:|..|:|.|
Mouse   835 EKSVEKIQRDVAHNHRLVPGPELEEKALVLKQLGETLTELKAHFPGLQSKMRVVLRVEVEAV--- 896

  Fly   749 EKFLKEEPDRLESALRRCKKLTGTLVTLKRLASVQEQRLPPNEPTISEETPRSADISAPDKPIPT 813
             |||||||.||:..|:||:.:|.||..::|  .|.|...||         |.:....:|.|
Mouse   897 -KFLKEEPQRLDGLLKRCRGVTDTLAQIRR--QVDEGMWPP---------PNNLLNQSPKK---- 945

  Fly   814 PRMGSFALSGGLAPENALDALLD-ELKTFSKPIAQQQQQQQQQQQQQQQQHQHQQLYEIRPEDSA 877
                       :|.|......|| |:...|.|:                     .|:|:    |.
Mouse   946 -----------VAAETDFSKGLDFEIPPPSPPL---------------------NLHEL----SG 974

  Fly   878 SDESAQAAVQSTVTTQ--ISQARLYTEASVNVQQATTGSMVIAVASGTVSAQAQAQRGVLTHQQS 940
            ..|......:||..|:  .:.::..|:.:|:|:.|              ....:.:|..||...:
Mouse   975 PAEGTPLTPKSTNPTKGLDASSKRNTDKAVSVEAA--------------ERDWEEKRAALTQYSA 1025

  Fly   941 QSQAQLMVHTNMGSLRRLHSYPSESDGELPGP-------PPTGPRASETSSSTSLANGGSSSKPP 998
            :...:|:..|....|:.:......|... |||       ||..|...:.:..|..:....|.:..
Mouse  1026 KDINRLLEETQAELLKAIPDLDCASKTH-PGPAPTPDHKPPKAPHGQKAAPRTEPSGRRGSDELT 1089

  Fly   999 VPERNAELITKVGHKRIPPPPPPRTS 1024
            ||....|..:|     .|||||||.|
Mouse  1090 VPRYRTEKPSK-----SPPPPPPRRS 1110

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32809	NP_001245466.1	AIP3	170..>247	CDD:427585	35/76 (46%)
Srcin1	XP_017170155.1	AIP3	273..>352	CDD:427585	36/82 (44%)
		SMC_N	<784..938	CDD:481474	57/185 (31%)
		Herpes_BLLF1	<1158..1509	CDD:282904