Protein Alignment CG32809 and Etl4

DIOPT Version :10

• Sequence 1: NP_001245466.1
• Gene: CG32809 / 31121
• FlyBaseID: FBgn0023531
• Length: 1264
• Species: Drosophila melanogaster
• Sequence 2: XP_063132338.1
• Gene: Etl4 / 291356
• RGDID: 1563437
• Length: 2028
• Species: Rattus norvegicus
• Alignment Length: 1562
• Identity: 324/1562 - (20%)
• Similarity: 532/1562 - (34%)
• Gaps: 593/1562 - (37%)

  Fly     7 SKDKSASSNQSVGGSSSSSSKKKRKGREG---------------------EDWQNEAKSG----- 45
            ||....||.|.   .:|...|.:|.|.||                     |..:.:.||.
  Rat    22 SKKDDLSSKQK---KTSRGEKTERTGSEGNLAEHQQVQTAVATAAQRKAAEAHKEQGKSNLHVTS 83

  Fly    46 ------RLPSNE-QGGDERRRAMR--RDDPRRHTLGG---DMLVYGSQ----------------- 81
                  |.|... ..|:.|.:..:  |:.||||||||   ...:.|.|
  Rat    84 QEDAACRRPKERLSNGNTRAQVSKPARNIPRRHTLGGPRSSKEILGMQTSEMDRKREAFLEHLKQ 148

  Fly    82 -HPH------AHQMAPQQQRAMDLEMSTRAQ------------KNKKNQPMRGYAPVNQGPLFDD 127
             :||      .||...:.|....:.:|.:|:            ..:...|...::|  |.|...|
  Rat   149 KYPHHATAIMGHQERLRDQALQCMLVSLQAELDIQRYLMKIESSQRTKSPKLSHSP--QPPNLGD 211

  Fly   128 DPGIMSE-----VETASTG-----FRRGGKQRSSLPVVRTPSKTLERPLGLVFLQYRSETKRALL 182
            ....:||     :|..|.|     |.||.:.|:||||||:.::|.||.||:::|||..|||:..:
  Rat   212 PVEHLSETSGDSLEAMSEGDVPSPFARGSRTRASLPVVRSTNQTKERSLGVLYLQYGDETKQLRM 276

  Fly   183 PNEITSIDTVRALFVRSFPRQLTMSYLEGPNVKIYIHDASKDMFYELEDVRSHLREIRDRSVLRL 247
            ||||||.||:|||||.:||:||||..||.|:|.|||.|.|::::|||.|||:    |:|||:|::
  Rat   277 PNEITSADTIRALFVSAFPQQLTMKMLESPSVAIYIKDESRNVYYELNDVRN----IQDRSLLKV 337

  Fly   248 FEST------------------------------------EVAAPPQILPGGP---GIPQPLPQA 273
            :...                                    ..|.||.::|..|   .:|..||.:
  Rat   338 YNKDPSHAFNHMAKAVNGDVRMQREIVYARGDGLVAPRPGSTAHPPHVIPNSPPSTPVPHSLPPS 402

  Fly   274 QANWDQDQSYFSEPEFDSDYKHQHIHKSKIGKQPAPYYVGSSQTLPRGMYSSERNKVSMGAPVKP 338
            .:......|                         .|..:..:.|:||...||        .||.
  Rat   403 PSRIPYGGS-------------------------RPMAIPGNATIPRDRLSS--------LPVS- 433

  Fly   339 LRSLNP-------RGSMEP----------LFP----YTPDQLY----------------SIPDGY 366
             ||::|       |..::|          :|.    |....||                .:||..
  Rat   434 -RSISPSPSAILERRDVKPDEDMSSKNLVMFRNEGFYADPYLYHEGRMSIASSHGGHPLDVPDHV 497

  Fly   367 TS-------------SPERSSRGNYEEPYYSQYGTR---------GAVVAPIIDEEQSDGTMTED 409
            .:             :|...:..:.|:..|.|...:         |:...|.......|..|. |
  Rat   498 IAYHRTAIRSASAYCNPSMQAEMHMEQSLYRQKPRKYPDSHLPALGSKTPPASPHRVGDLRMI-D 561

  Fly   410 QYALYGIKVGP---------GPNRLTHR---GNQIY----------------------------- 433
            .:....:. ||         .|:|.:.:   |..:|
  Rat   562 MHPQLNVH-GPPHTLQPDRASPSRQSFKKESGTLVYIEKPRNTPGLSGLVDLGPPLVEKQVFAYS 625

  Fly   434 DPTRPEDLH-RIRVEHMERQLANLTGLVQKALVNQNPQIAPLAVPTLDPNYLVVPSQMQANGSGD 497
            ..|.|:|.. |.|::.||:|:|:||||||.||. :.|..:.....:.:.......::.||.|:|
  Rat   626 TATIPKDRETRERMQAMEKQIASLTGLVQSALF-KGPITSSSKEASSEKMMKATANRNQAEGAG- 688

  Fly   498 ELYIREKAPKLGKNSCQKSVSFEKSVSFSDDIQGIPKSHNPLHAAETKPTKPAIKSSTLPRTSSQ 562
                            ...||..||:.                         |::||.
  Rat   689 ----------------AAHVSAGKSLG-------------------------AVESSL------- 705

  Fly   563 ERDRLKPPPPPKPIVLAQTAHPNYRADIALAPEVYNHLRGLQKKAKDLRMEVRTLRRLSQAQAVA 627
                  ||..|.|               |....::..|..:::...:||::::.:|:|.......
  Rat   706 ------PPSQPLP---------------AGTSPIHTSLLDMRRNVAELRLQLQQMRQLQLQNQEI 749

  Fly   628 VREDIKGTFMRIRATLLASSGSFWDHQGDQDATRISREEELYKQEVIRLEKDLSDLEGSVENLRG 692
            :|..:|...:.|.:.:..:.....| ...:..|.:.:|.:.|..|..|:.|.|.:||..||:|:.
  Rat   750 LRAMMKKAELEISSKVKETMKRLED-PVQRQRTLVEQERQKYLHEEERIVKKLRELEDFVEDLKK 813

  Fly   693 EVINRRTRVNMTAVEDMALVLSRASKTVAELKLKFPSLSNGLRCILSNEMEKVVREEKFLKEEPD 757
            :..:....|.:..|||.|.:|.:..:.||.||.:||:|.|.:|.:|..|:|.|    :||||||.
  Rat   814 DSSSAGRVVTLKDVEDGAFLLRQVGEAVATLKGEFPTLQNKMRAVLRIEVEAV----RFLKEEPH 874

  Fly   758 RLESALRRCKKLTGTLVTLKR-----------------------------LASVQEQRLPPNEPT 793
            :|:|.|:|.:.:|..|..|:|                             |...:|....|.:|
  Rat   875 KLDSLLKRVRSMTDVLTMLRRHVTDGLLKGTDAAQAAQYVAMEKATAAEVLKHQEETTHAPGQP- 938

  Fly   794 ISEETPRSADISAPDKPIPT--------------PRMGSFALS-------GGLAPENAL------ 831
            :...|....|:.:...|:.|              |...|.||:       ||..|..|:
  Rat   939 LHCSTGSPGDVKSEVVPLSTMTVHHVQSSPVVMQPSQHSSALTNPAQNLPGGTRPHTAISQEVIS 1003

  Fly   832 ---------------------DALLDELKTFS---KPIAQQQQQQQQQQQQQQQQHQHQQLYEIR 872
                                 ...::|:.:.|   :.::.::.:::.::::|..:|.:.:.:|
  Rat  1004 SPQSAPAPQSPQTPLNGSSVQSLFIEEIHSVSAKNRAVSIEKAERKWEEKRQNLEHYNGKEFE-- 1066

  Fly   873 PEDSASDESAQAAVQSTVTTQISQARLYTEASVNVQQATTG------SMVIAVASGTVSAQAQAQ 931
                                     :|..||.||:.::...      |..:|...||...:.:
  Rat  1067 -------------------------KLLEEAQVNIMKSIPNLEMPPTSSPVAKGDGTAVDKLE-- 1104

  Fly   932 RGVLTHQQSQSQAQLMVHTNMGSLRRLHSYPSESDGELPGPPPTGPRAS---------------- 980
               |:.....|:.:|                .:..|:.|.|||..||.|
  Rat  1105 ---LSEDSPNSEQEL----------------DKLGGKSPPPPPPPPRRSYLPGSGLTTTRSGDVI 1150

  Fly   981 ETSSSTSLANGGSSSKPPVPERNAELITKVGHKRIPPPPPPRTSSRSPLASPTSPNVPPNQA--- 1042
            .|....|::...|....|.|:..|        .:.||..|      :|...|:.|.||.:.:
  Rat  1151 YTGRKESMSKVTSEEPGPTPQTRA--------TKCPPEEP------APACVPSPPPVPASSSKDG 1201

  Fly  1043 -----------------AAATVNLIPNSNSNASANANANANSNATGNKGIVGETTSVVSGDTSSG 1090
                             ..:..::.|||::..|     .|:|:....:          .|.|:..
  Rat  1202 EEEEEGDKIMAELQAFQRCSFTDVNPNSHAEQS-----RADSHLKDTR----------PGATAPP 1251

  Fly  1091 DNSSGNESG--NDHVQRQVALEMRHQELLKK----QKMLQEQYQRLQQMSKLPS---------VD 1140
            ....|:..|  ::.:|.   ||..|:::.|.    :...|.:.|::...:..||         ||
  Rat  1252 KEKKGSSGGWRSEQLQN---LEFFHEDVRKSDVECENGPQAESQKVTAGALRPSGPPKWGRAMVD 1313

  Fly  1141 VASSSSSSA--------QDIASGSNT---------------------LRKLGSETNIQQKIAALS 1176
            ..|.:|.::        ::||...|.                     |..|..:.|...|::.|.
  Rat  1314 SLSDTSRTSECRADTFTEEIAPNKNLYQDGRNYSQKNVPKVSFNFTGLNSLEGDINKGSKVSGLQ 1378

  Fly  1177 LA 1178
            .|
  Rat  1379 YA 1380

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32809	NP_001245466.1	AIP3	170..>247	CDD:427585	45/76 (59%)
Etl4	XP_063132338.1	None