DRSC/TRiP Functional Genomics Resources

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Protein Alignment hfw and islr2

DIOPT Version :9

Sequence 1:NP_001259135.1 Gene:hfw / 31120 FlyBaseID:FBgn0001189 Length:611 Species:Drosophila melanogaster
Sequence 2:NP_001013541.1 Gene:islr2 / 541396 ZFINID:ZDB-GENE-050320-95 Length:712 Species:Danio rerio


Alignment Length:206 Identity:53/206 - (25%)
Similarity:79/206 - (38%) Gaps:57/206 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly   400 VDCSNLGLVELPQRLPDNTFMLNITNNKITSLGDYFHTNPTY-------HN-------------- 443
            |||:...|||:|..||.|...|:::.|||..|......|.|.       ||              
Zfish    37 VDCAYKDLVEVPVGLPSNASTLSLSANKIKVLKSKTFVNVTQVTSLWLAHNEIITVERDTLAPLI 101

  Fly   444 -INRLLADNNQISSIYEFEGTKFIETFQRIYMRNNSLSKIPEYFLNNALMDSGLGRRIYLAGNK- 506
             :..|...||:|.. :.:|....:...|.:.|.||.:..||:...:| |.|.   |.|.:..|| 
Zfish   102 QLKNLDISNNKIVH-FPWEDLANLGALQLLKMNNNEMVSIPKNAFSN-LKDL---RSIRINNNKF 161

  Fly   507 ----------------LQ-------CDCNSAKTLQNWLKERSSDIPDYMEIRCRNMPQRVIELQE 548
                            ||       |.|| .:.|::|:.:.|..||:...|.| :.|..:...|.
Zfish   162 TTIVQGTFDSLAAMSHLQIFHNPFICSCN-LEWLRDWILKSSISIPEQNNIAC-DAPSHLKGSQV 224

  Fly   549 AKL----CQSP 555
            ..:    |::|
Zfish   225 TSMPKLNCKAP 235

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
hfwNP_001259135.1 LRR_8 235..294 CDD:290566
leucine-rich repeat 237..259 CDD:275378
leucine-rich repeat 260..283 CDD:275378
leucine-rich repeat 284..304 CDD:275378
leucine-rich repeat 420..443 CDD:275378 7/29 (24%)
leucine-rich repeat 444..465 CDD:275378 5/20 (25%)
leucine-rich repeat 466..497 CDD:275378 9/30 (30%)
leucine-rich repeat 498..509 CDD:275378 6/34 (18%)
islr2NP_001013541.1 leucine-rich repeat 35..53 CDD:275380 8/15 (53%)
LRR_RI <47..>184 CDD:238064 33/141 (23%)
LRR_8 53..113 CDD:290566 13/59 (22%)
leucine-rich repeat 57..78 CDD:275380 6/20 (30%)
leucine-rich repeat 79..102 CDD:275380 2/22 (9%)
LRR_8 102..161 CDD:290566 17/63 (27%)
leucine-rich repeat 103..126 CDD:275380 5/23 (22%)
leucine-rich repeat 127..150 CDD:275380 8/23 (35%)
leucine-rich repeat 151..174 CDD:275380 4/25 (16%)
LRRCT 183..>221 CDD:214507 11/39 (28%)
IG_like 252..345 CDD:214653
Ig 256..345 CDD:299845
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR24366
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
11.100

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