DRSC/TRiP Functional Genomics Resources

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Protein Alignment hfw and CG7896

DIOPT Version :9

Sequence 1:NP_001259135.1 Gene:hfw / 31120 FlyBaseID:FBgn0001189 Length:611 Species:Drosophila melanogaster
Sequence 2:NP_651754.1 Gene:CG7896 / 43552 FlyBaseID:FBgn0039728 Length:1392 Species:Drosophila melanogaster


Alignment Length:479 Identity:92/479 - (19%)
Similarity:172/479 - (35%) Gaps:161/479 - (33%)


- Green bases have known domain annotations that are detailed below.


  Fly   216 NLHVRNMTVEDMDLSN-PIFRSLQSLAVTDGNITRLV-NAFPRLSALKCLNISNNNISEIHSRAV 278
            :|::.:..::.:|.:: .:.|||:||.::...||.:. ..|..:.|||.|::|.|::..|...|:
  Fly   308 HLNLSSNMLQQLDYTHMQVVRSLESLDISRNTITTITPGTFREMGALKYLDLSLNSLRTIEDDAL 372

  Fly   279 KDVPHLEFFGMSNNNLSLVP---------------HRNQNKNITLDISGNMR---MLCTPLNEII 325
            :.:..|:...:.:||:.|||               ..|:...::.:|.|:::   :....|:..:
  Fly   373 EGLDSLQTLIIKDNNILLVPGSALGRLPQLTSLQLDYNRVAALSAEILGSLQAGDITTLSLSRNV 437

  Fly   326 YTESINFLNPKHSYCQYNATHTWFQSTDKVSV----------------EQLENRKRCVTNCP-VI 373
            ..|.     |..|:..:::.||...|.:.::|                :..:||...:...| |:
  Fly   438 IREL-----PPGSFQMFSSLHTLDLSGNSLAVINADTFAGLESTLMALKLSQNRLTGLGGAPWVL 497

  Fly   374 PNYGSCNCTLENIMIIQDNQSKPQCHVDCSNLGLVELPQRL---PDNTFMLNITNNKITSL---- 431
            |...|                     :|.|...|.|||..:   .:|...||::.|.:|.|    
  Fly   498 PELRS---------------------LDLSGNTLTELPSTIFEELENVQSLNLSGNHLTPLTGAL 541

  Fly   432 ---------------------GD-----------YFHTNPTYH----------NINRLLADNNQI 454
                                 ||           |.:.|....          ||:.:...||:|
  Fly   542 FKPLDRLQVIDLSGCNIRQISGDLLAGLQDLKHIYLNDNQLQELQDGSFVNLWNISSIDLSNNRI 606

  Fly   455 SSIYEFEGTKFIET--FQRIYMRNNSLSKIP-EYFLNNALMDSGLG-RRIYLAGNKLQCDCNSAK 515
            .||   ....|:..  .|::.:..|.||... |||      ::|.| ..:.::.|:|        
  Fly   607 GSI---RSGAFVNVMKLQKLDLHGNQLSAFKGEYF------NTGTGIEELDISDNQL-------- 654

  Fly   516 TLQNWLKERSSDI-PDYMEIRCRNMPQRVIELQEAKLCQSPPDWTDYIYYLIAAEVLLLLALITK 579
               ::|...|..| |...|||..|..                      :....||::..|..:..
  Fly   655 ---SYLFPSSFRIHPRLREIRAANNK----------------------FSFFPAELISTLQYLEH 694

  Fly   580 VSYDYWVFKTAGYLPWPASKMPKL 603
            :...:...||...|.:  :::|:|
  Fly   695 IDLSHNQLKTIEELDF--ARLPRL 716

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
hfwNP_001259135.1 LRR_8 235..294 CDD:290566 18/59 (31%)
leucine-rich repeat 237..259 CDD:275378 6/22 (27%)
leucine-rich repeat 260..283 CDD:275378 7/22 (32%)
leucine-rich repeat 284..304 CDD:275378 7/34 (21%)
leucine-rich repeat 420..443 CDD:275378 9/68 (13%)
leucine-rich repeat 444..465 CDD:275378 6/20 (30%)
leucine-rich repeat 466..497 CDD:275378 8/33 (24%)
leucine-rich repeat 498..509 CDD:275378 2/10 (20%)
CG7896NP_651754.1 LRR_8 109..172 CDD:290566
leucine-rich repeat 109..132 CDD:275380
LRR_RI <132..338 CDD:238064 7/29 (24%)
leucine-rich repeat 133..161 CDD:275380
LRR_8 160..220 CDD:290566
leucine-rich repeat 162..185 CDD:275380
leucine-rich repeat 186..209 CDD:275380
leucine-rich repeat 210..233 CDD:275380
LRR_8 232..290 CDD:290566
leucine-rich repeat 234..257 CDD:275380
leucine-rich repeat 258..281 CDD:275380
LRR_RI 273..535 CDD:238064 51/252 (20%)
LRR_8 281..338 CDD:290566 7/29 (24%)
leucine-rich repeat 282..329 CDD:275380 2/20 (10%)
LRR_8 328..388 CDD:290566 18/59 (31%)
leucine-rich repeat 330..353 CDD:275380 6/22 (27%)
leucine-rich repeat 354..377 CDD:275380 7/22 (32%)
leucine-rich repeat 378..401 CDD:275380 6/22 (27%)
leucine-rich repeat 402..425 CDD:275380 3/22 (14%)
leucine-rich repeat 428..451 CDD:275380 4/27 (15%)
LRR_8 429..487 CDD:290566 9/62 (15%)
leucine-rich repeat 452..473 CDD:275380 4/20 (20%)
leucine-rich repeat 477..497 CDD:275378 3/19 (16%)
LRR_8 498..558 CDD:290566 14/80 (18%)
leucine-rich repeat 500..523 CDD:275380 7/43 (16%)
LRR_RI 502..769 CDD:238064 52/280 (19%)
leucine-rich repeat 524..547 CDD:275380 5/22 (23%)
leucine-rich repeat 548..571 CDD:275380 2/22 (9%)
LRR_8 572..630 CDD:290566 12/60 (20%)
leucine-rich repeat 572..595 CDD:275380 2/22 (9%)
leucine-rich repeat 596..619 CDD:275380 7/25 (28%)
LRR_8 619..678 CDD:290566 19/97 (20%)
leucine-rich repeat 620..643 CDD:275380 8/28 (29%)
leucine-rich repeat 644..667 CDD:275380 5/33 (15%)
LRR_8 666..726 CDD:290566 13/75 (17%)
leucine-rich repeat 668..691 CDD:275380 7/44 (16%)
leucine-rich repeat 692..715 CDD:275380 3/24 (13%)
LRR_8 714..774 CDD:290566 2/3 (67%)
leucine-rich repeat 716..739 CDD:275380 1/1 (100%)
leucine-rich repeat 740..761 CDD:275380
leucine-rich repeat 764..789 CDD:275380
leucine-rich repeat 790..810 CDD:275380
leucine-rich repeat 818..850 CDD:275380
leucine-rich repeat 863..883 CDD:275378
LRR_RI <878..1070 CDD:238064
LRR_8 884..944 CDD:290566
LRR_4 884..925 CDD:289563
leucine-rich repeat 884..907 CDD:275380
leucine-rich repeat 908..933 CDD:275380
leucine-rich repeat 934..955 CDD:275380
leucine-rich repeat 958..982 CDD:275380
leucine-rich repeat 983..1055 CDD:275380
leucine-rich repeat 1009..1033 CDD:275380
leucine-rich repeat 1058..1085 CDD:275380
TPKR_C2 1121..1168 CDD:301599
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - P PTHR24366
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
11.100

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