Protein Alignment hfw and Lrrc3b

DIOPT Version :10

• Sequence 1: NP_569933.2
• Gene: hfw / 31120
• FlyBaseID: FBgn0001189
• Length: 611
• Species: Drosophila melanogaster
• Sequence 2: NP_666164.1
• Gene: Lrrc3b / 218763
• MGIID: 2384996
• Length: 259
• Species: Mus musculus
• Alignment Length: 208
• Identity: 55/208 - (26%)
• Similarity: 85/208 - (40%)
• Gaps: 42/208 - (20%)

  Fly   366 CVTNCPVIPNYGSCNCTLENIMIIQDNQSKPQCHVDCSNLGLVELPQRLPDNTFMLNITNNKITS 430
            |..:..:.|.  .|.|:           |....:|.|||..|.|:|:.||..|.:|.:.:|:|||
Mouse    27 CFHSASMCPK--GCLCS-----------SSGGLNVTCSNANLKEIPRDLPPETVLLYLDSNQITS 78

  Fly   431 LGDYFHTNPTYHNINRLLADNNQISSIYE--FEGTKFIETFQRIYMRNNSLSKIPEYFLNNALMD 493
            :.:....:  .|.:..|....|.|..|.|  |:|.  .||.|.:.:.:|.:..:.:...||
Mouse    79 IPNEIFKD--LHQLRVLNLSKNGIEFIDEHAFKGV--AETLQTLDLSDNRIQSVHKNAFNN---- 135

  Fly   494 SGLGRRIYLAGNKLQCDCNSAKTLQNWLKERSSDIPDYMEIRCRNMPQRVIE----------LQE 548
              |..|..:|.|...|||    |||..|:..:|:......:.|:.   .|::          ..:
Mouse   136 --LKARARIANNPWHCDC----TLQQVLRSMASNHETAHNVICKT---SVLDEHAGRPFLNAAND 191

  Fly   549 AKLCQSPPDWTDY 561
            |.||..|...|||
Mouse   192 ADLCNLPKKTTDY 204

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hfw	NP_569933.2	LRR	<198..>313	CDD:443914
		leucine-rich repeat	237..259	CDD:275378
		leucine-rich repeat	260..283	CDD:275378
		leucine-rich repeat	284..304	CDD:275378
		leucine-rich repeat	420..443	CDD:275378	5/22 (23%)
		leucine-rich repeat	444..465	CDD:275378	7/22 (32%)
		leucine-rich repeat	466..497	CDD:275378	6/30 (20%)
		leucine-rich repeat	498..509	CDD:275378	3/10 (30%)
Lrrc3b	NP_666164.1	LRRNT	33..68	CDD:214470	14/47 (30%)
		LRR 1	65..86		6/20 (30%)
		leucine-rich repeat	66..89	CDD:275378	6/24 (25%)
		LRR_8	69..125	CDD:404697	17/59 (29%)
		LRR 2	89..110		6/20 (30%)
		leucine-rich repeat	90..113	CDD:275378	7/24 (29%)
		LRR 3	114..135		3/20 (15%)
		leucine-rich repeat	115..138	CDD:275378	5/28 (18%)