Protein Alignment hfw and lron-1

DIOPT Version :9

• Sequence 1: NP_001259135.1
• Gene: hfw / 31120
• FlyBaseID: FBgn0001189
• Length: 611
• Species: Drosophila melanogaster
• Sequence 2: NP_510424.4
• Gene: lron-1 / 181553
• WormBaseID: WBGene00008093
• Length: 607
• Species: Caenorhabditis elegans
• Alignment Length: 481
• Identity: 105/481 - (21%)
• Similarity: 193/481 - (40%)
• Gaps: 103/481 - (21%)

  Fly    86 TTASSLAETQSMS-DPGSVTDTTSTSTSHS----TSTTSTTSPAPLPPAAPEQPEYLKHCFYAEE 145
            |..|:..|..|:: |.||..|....|.|:|    .|.|.:.:|....|....|...:|..|....
 Worm    28 TCTSTRYEAVSINCDGGSSLDAVLESLSNSPQAIDSLTISNTPIEKMPGYAFQGFQIKKLFLRNN 92

  Fly   146 QLCG---HTFDGRAETSEGQGSTVAQSEAQNRGGQGNSQCQCREHPTRPNSWYCCNISQLTMISS 207
            .|..   :||.|..|.|        ..|.:.||...:.         .|.|.... :.||.::|.
 Worm    93 GLRSFHPNTFTGNLENS--------LEELEIRGNYIDG---------IPQSGVSI-LKQLKILSL 139

  Fly   208 CSNISKWT------NLHVRNMTVEDMDLSNPIFRSLQSLAVTDGNITRL-VNAFPRLSALKCLNI 265
            ..|:.::.      :.|.|:              ||..|.::..|:|.: ......|..|..|::
 Worm   140 PDNLIEYVQDNAFLSYHSRD--------------SLLKLDLSANNLTAIHPTGLLGLENLSQLSL 190

  Fly   266 SNNNISEIHSRAVKDVPHLEFFGMSNNNLSLVPHRN----QNKNITLDISGNMRMLC------TP 320
            ..|.:|||.|:|::::|.||...:..|.:..:...:    ..|:::|::: .:|::.      ||
 Worm   191 DKNLLSEIPSQALENIPSLEDLSLGVNRIHTISRNSLPLPNLKSLSLEVN-QIRLIPSDSFSETP 254

  Fly   321 LNEIIY--------TESINFLN---PKHSYCQYNATHTWFQSTDKVSVEQLENRKRCVTNCPVIP 374
            |...:|        .::..||:   .|......|...|..|:..|:||:|.   |.|:
 Worm   255 LLSYLYLGNNLLTSIDASMFLHIGGLKVLSMSNNKDITSIQANGKLSVQQF---KLCI------- 309

  Fly   375 NYGSCNCTLENIMIIQDNQSKPQCHV-DCSNLGLVELPQRLP--DNTFMLNITNNKITSLG-DYF 435
                  |    |:..|...|..:..: ||| :..:| |:.|.  .:..::.::.|:||.:. |.|
 Worm   310 ------C----ILAFQHAPSLIRLELFDCS-ISRIE-PKSLQKVQHIQVILLSRNQITRISHDTF 362

  Fly   436 HTNPTYHNINRLLADNNQISSIYEFEGTKFIETFQRIYMRNNSLSKIPEYFLNNALMD---SGLG 497
            ...|   .::.|....|.|:::.:|..:: :.....:.:.:|.|..:|...:.::||.   |.:.
 Worm   363 SNLP---ELSELDLSGNSINAVDDFAFSQ-LPMLTSLDLSSNRLESLPSNVIYDSLMQKKTSPVQ 423

  Fly   498 RRIYLAGNKLQCDCNSAKTLQNWLKE 523
            |::.:..|..:|| .....|:.||::
 Worm   424 RKLSIQNNPWRCD-KDLMWLRKWLRD 448

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hfw	NP_001259135.1	LRR_8	235..294	CDD:290566	18/59 (31%)
		leucine-rich repeat	237..259	CDD:275378	5/22 (23%)
		leucine-rich repeat	260..283	CDD:275378	8/22 (36%)
		leucine-rich repeat	284..304	CDD:275378	3/23 (13%)
		leucine-rich repeat	420..443	CDD:275378	6/23 (26%)
		leucine-rich repeat	444..465	CDD:275378	4/20 (20%)
		leucine-rich repeat	466..497	CDD:275378	6/33 (18%)
		leucine-rich repeat	498..509	CDD:275378	2/10 (20%)
lron-1	NP_510424.4	PRK15370	<58..>289	CDD:185268	52/263 (20%)
		leucine-rich repeat	85..109	CDD:275380	7/23 (30%)
		leucine-rich repeat	110..133	CDD:275380	5/32 (16%)
		leucine-rich repeat	134..157	CDD:275380	3/22 (14%)
		leucine-rich repeat	161..184	CDD:275380	5/22 (23%)
		leucine-rich repeat	185..208	CDD:275380	8/22 (36%)
		leucine-rich repeat	209..231	CDD:275380	3/21 (14%)
		leucine-rich repeat	232..255	CDD:275380	4/23 (17%)
		leucine-rich repeat	256..279	CDD:275380	3/22 (14%)
		leucine-rich repeat	280..319	CDD:275380	13/58 (22%)
		leucine-rich repeat	320..343	CDD:275380	6/24 (25%)
		LRR_8	343..402	CDD:338972	11/62 (18%)
		leucine-rich repeat	344..367	CDD:275380	6/25 (24%)
		leucine-rich repeat	368..391	CDD:275380	4/23 (17%)
		leucine-rich repeat	392..410	CDD:275380	3/17 (18%)
		leucine-rich repeat	414..435	CDD:275378	5/20 (25%)
		LRRCT	431..>472	CDD:214507	6/19 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000