Protein Alignment dor and Vps11

DIOPT Version :10

• Sequence 1: NP_477286.2
• Gene: dor / 31118
• FlyBaseID: FBgn0000482
• Length: 1002
• Species: Drosophila melanogaster
• Sequence 2: NP_730776.1
• Gene: Vps11 / 317987
• FlyBaseID: FBgn0052350
• Length: 830
• Species: Drosophila melanogaster
• Alignment Length: 873
• Identity: 157/873 - (17%)
• Similarity: 286/873 - (32%)
• Gaps: 311/873 - (35%)

  Fly   222 YPITGLKLLRVPNSSRYIIVVTSPECIYTFQETLKA-EERSLQAIFAGYVSGVQEPHCEERKTDL 285
            :.|..:..:::||::..       .| |.|.|:..: |||:::.:.           |::.:..|
  Fly    14 FNIIVVPFVKIPNTAEI-------SC-YCFPESKSSTEERNIKLVI-----------CDKNRNIL 59

  Fly   286 TFSQ----LRFFAPPNSKYPKQWAWLCGEGIRVGELSIEANSAATLIGNTLINLDFEKTMHLSYG 346
            .:..    :.|.:|...|           .|.:..|: ..||.||      :..|....:|:...
  Fly    60 IYLSNWECITFKSPSTRK-----------AIALCSLT-SNNSLAT------VTPDINNGIHIDIF 106

  Fly   347 ERRLNTPKAFVLTEYHAVLLYAD-----HVRAICLLNQEQVYQEAFDEA-------------RVG 393
            :  ||.     ||:..|..:.|.     ....:| ||.:.:..:.|..|             ::.
  Fly   107 D--LNR-----LTKKQAAPIIASAYTQPSSTPLC-LNADVIDDKLFALAIGLGNGDILLHYGKIT 163

  Fly   394 KPLS--IERDELTGS-------------------IYVYTVKTVFNLRVTREERNVWRIYL--DKG 435
            |..|  |.:..::|:                   ::|..|:.|:...:..:.....:..|  |||
  Fly   164 KNFSANIRQHTVSGNAVNGIHFDFKTQPLDTTQIMFVTCVQGVYCFMLKEKCIMDTKFVLDNDKG 228

  Fly   436 --QYELATAHAAEDPEHLQLVLCQRADAAFA------------DGSYQVAA--DYY---AETDKS 481
              .|......|.....:..:::..||||.:.            :|:.:..|  .:|   ...:.:
  Fly   229 NLNYRSIMCKAGGGEINDSMLVVGRADAVYCYTPEGRGPCFAIEGAKECLAWVGHYLIVGVKNSN 293

  Fly   482 FEEVCLKFMVLPDKRPIINYVKK-----------RLSRVTTKPMETDE-----LDEDKMNI-IKA 529
            .::.....:||..:..||.:.::           ....:.|...:||.     |:::.::: |:.
  Fly   294 LKQNATTLIVLDTENKIIVFQRQFQELFYVISENNFCYIVTNSGDTDACNMLMLEKNSIDVNIRL 358

  Fly   530 LV---IWLIDLYLIQINMPDKDEEWRSSWQTEYDEFMMEAHVLSCTRQNRETVRQLIAEHADPRN 591
            ||   ::.|.|.|:.      .|.:.||.:|....|....|:|.
  Fly   359 LVEKHMYNIALRLLH------REGYTSSPETALVRFQYGNHLLQ--------------------- 396

  Fly   592 MAQFAIAIGDYDEVVAQQLKA----ECYAEALQTLINQRNPELFYKYAPELITRLPKPTVDALMA 652
                   .||:.....:.:|.    :.||...:.|.::.|     .|....:|...|..
  Fly   397 -------KGDFSRATQEFIKTIGFIKPYAVISKLLYSRYN-----TYLLNYLTEWKKKN------ 443

  Fly   653 QGSRLEVEKLVPTLIIMENREQREQTQRYLEFAIYKLNTTNDAIHNFLLHLYAEHEPKLLMKYL- 716
            :.|.... :|:...|   .|:|.|...:..:|..||....            .:|...|...|.
  Fly   444 ESSSCHT-RLIECCI---KRDQIEHEMQQDDFKHYKSPAK------------IKHLATLSKMYFA 492

  Fly   717 -----EIQGRDESLVHYDIYYA-HKVCTDL----------DVKEARVFLE-----------C--M 752
                 ::...:|.|:|..:.|. ..:..||          :|||::..|.           |  |
  Fly   493 CTPSNQVPVEEEHLLHQLLEYGPASLAVDLTTYLNNITFENVKESKNILSFCSILADHNDYCAKM 557

  Fly   753 LRKWISA---VDLALTFDM--------KLAKETASRPSD-----------SKIRRKLWL------ 789
            |.|.|.|   .|..|.|.:        :|.|.|:|..||           :.|..:|:.
  Fly   558 LAKIIEAFPVCDEKLLFYLLVFYFKLWRLDKVTSSFVSDFIKTHSLRMDKTIIVSRLYTFFNVTQ 622

  Fly   790 RIAYHD------------------IKGTNDVKKALNLLKECDLLRIED-----------LLPFFA 825
            ||..|.                  ||...||....||.|...|:.::.           :.|.|.
  Fly   623 RIHGHQKNTGTLHNETIDKCIENLIKNNPDVALNENLSKRSFLMMLKSSCSTEEIKAIKIKPIFK 687

  Fly   826 DFEKIDNFKEAICDA------LRDYNQRIQELQREMAETTEQTDRVTAELQQLRQHSLTVE-SQD 883
                 |....:|.|:      :.::|::|:..:..::..|..                .:| ..|
  Fly   688 -----DRLLRSIVDSANELKLVENFNEKIKRSRSMLSLYTNN----------------PIEFRND 731

  Fly   884 TCEICEMMLLVKPFFIFICGHKFHSDCL 911
            .|:||..||.::..: |:|.|.||.:||
  Fly   732 KCDICREMLSMQSIY-FLCQHSFHEECL 758

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dor	NP_477286.2	Pep3_Vps18	311..464	CDD:461557	36/195 (18%)
		Clathrin	650..783	CDD:459884	37/184 (20%)
		RING_Ubox	883..981	CDD:473075	13/29 (45%)
Vps11	NP_730776.1	RING-H2_Vps11	731..777	CDD:438349	13/29 (45%)