Protein Alignment Mur2B and dpy-6

DIOPT Version :9

• Sequence 1: NP_001284789.1
• Gene: Mur2B / 31111
• FlyBaseID: FBgn0025390
• Length: 1795
• Species: Drosophila melanogaster
• Sequence 2: NP_509435.2
• Gene: dpy-6 / 181099
• WormBaseID: WBGene00001068
• Length: 1254
• Species: Caenorhabditis elegans
• Alignment Length: 1444
• Identity: 388/1444 - (26%)
• Similarity: 574/1444 - (39%)
• Gaps: 452/1444 - (31%)

  Fly   401 PETPATAATTREPLNDINKYQYKRYTYGT--DKNDVTEA--PEIKSPLKG--LHLSENIVILPET 459
            |..|...:||...:|:.|      ...|.  |.|....:  .||::.:.|  :....||....|.
 Worm    58 PSNPFDVSTTISSINNDN------VDIGPSGDSNPTGSSWFQEIEATVGGQTVKSEHNIDSSVEV 116

  Fly   460 TTTTTTTTKPVVLTCPTISPPDTTPKPSTTTAVTKSTPKISSTEQHSTTTAKTTTTKRPTTVTEK 524
            ....||:|.......||.....|||:..|...|..|  |..|....|||  :.:||..||  ||.
 Worm   117 EKKVTTSTDASTTNAPTTGKDSTTPEIITGIVVINS--KSESVTDMSTT--RFSTTLSPT--TEL 175

  Fly   525 TSSATEKPRTTVVTTTTQKRSTTTHNTSPDTKTTIRSTTLSPKTTTTPSTTTPSTTTPSTTTPST 589
            .:|    |.|.|.|.:    ||:|..||||..|.|    .||..|   :|||.:|||  :..||.
 Worm   176 LTS----PETLVSTDS----STSTEQTSPDNTTEI----ASPMET---NTTTEATTT--SVEPSV 223

  Fly   590 TTPST---TTPSTTTPSTTTTV-KVSTHRPRTTSQKTTTASTTTKKTTTSPKTTKTTDIPTSTTS 650
            :|.::   ||.:....||||.: :|||    ||.:.||||.:||||:||  |...||:.||.||:
 Worm   224 STLASEDETTVTAIAESTTTVIAEVST----TTEEPTTTAESTTKKSTT--KAPATTEEPTPTTT 282

  Fly   651 KLSTTTQKTTTTTHKFTAATTSTEKP--------------------------------------- 676
            :..|||:..|:||   |::.||||||
 Worm   283 EEVTTTEAETSTT---TSSETSTEKPTTPLIDNKIAGPATGKPETTHFPVTGTTPNFDTATETPF 344

  Fly   677 ------KTTTEKTSTVSTTTKKSTESSPKPTSSTGK------PTTTPKPSTRTTPTTTKVT---- 725
                  |.|..||: .:.||:::||.:..|...|.|      |.|| .|...||.||:..:
 Worm   345 VAKSEDKMTLSKTA-ATETTQQTTEVTDGPEKETTKNVSIEIPITT-VPLVETTSTTSTASKESD 407

  Fly   726 ---TTTQITTTTPLRSSTETTSTQPP----TTT----TPQPTTTTTLTVTPK------------- 766
               ||.::..||....|||:.:|..|    |||    .|:||...|:.||||
 Worm   408 GFHTTLKLKVTTADSDSTESATTVKPFNEETTTKSHVVPKPTKKGTVKVTPKLELSFDEPTEITK 472

  Fly   767 -------------TSTTTTTTEKPI-----------------TSSPKPTTTTQKTTSTAPNTTKV 801
                         |::||||||||:                 :::..||||.:.||:|..:.|:.
 Worm   473 APHPVKPRKTTTTTTSTTTTTEKPVITEGSTTNKQPTTSEHESTTEVPTTTEEPTTTTGQHKTEK 537

  Fly   802 AITTQKETTPTQSTSTT--IFTRKTTTNNPEPTSTEKPITSTTPKPSTTTPKTSTVASSTEKTTI 864
            ||||::.|| |:.:|||  :.|.:...|...|.:||.|  :||.:|::|...|:|....|.:.|:
 Worm   538 AITTEEPTT-TEESSTTEEVTTTEEPANTGNPPTTENP--TTTEQPTSTAESTTTALPFTTEQTV 599

  Fly   865 SSPKPTT-EKS--TENPTTNSVKTSALTSSTQRATSTTSEPTKTTQNITTTTPKPTTLKTSTQEA 926
            ::.:||| |||  |:.|||.....|...:||.:..|||.||| ||...||||...||.|.:|.|.
 Worm   600 TTEEPTTAEKSTATQKPTTTQESVSTEKTSTTKKASTTEEPT-TTDEPTTTTESSTTGKATTPEL 663

  Fly   927 TTSTQKVST--VTITTKKATESSPLTTLSTEEPNTT------PKPLRTTTPTTTSVTATTRITTT 983
            :|::::.:|  :.|||:.:|        :||||.||      ...:.||...|||.|:||...|:
 Worm   664 STTSEETTTTELKITTEGST--------TTEEPTTTAIFAEASTGIITTDEETTSTTSTTPEITS 720

  Fly   984 T---ISESSTETTSTQKPKSTTP---------------------------------TSTTRTTPK 1012
            |   ::||:...||....:|:||                                 ||||.:...
 Worm   721 TKEIVTESAITQTSVSVVESSTPRQLPERWKAIVNKFKHNLEVLKEKKRLLKEKESTSTTGSDSS 785

  Fly  1013 VTTVIVSTQNPTTTTSKTSTVTITTP--NPSPSTQRPTTTTRQPTSITASTTSIGTTRIPTTTNP 1075
            .||.:|:......||::...|..|||  ....:||..||||   |:.|..|||..||..|||
 Worm   786 ETTTVVAENIDEVTTTEKEKVVQTTPITTEKSTTQEETTTT---TTTTEKTTSKTTTEKPTT--- 844

  Fly  1076 QNSTSSTDLTTVTRPPCPDPDSTSDKNTNTACTQELQQVNLLELQSPQKQEQFTHTRTHTALTGS 1140
              |.|:|..||.:.|      ||::..|             ::..|...:|..|...|.|
 Worm   845 --SESATTETTTSEP------STTESTT-------------VDTSSATTEESSTAAETTT----- 883

  Fly  1141 RNTLGGQEVPDYMDDAPSSAEAESGQATTAKAPTMSTLAAAHLLQKLFHIISTTPPSREHAPTQR 1205
                               ..||:.:.||::       :||.:          |..|.|:...|
 Worm   884 -------------------TSAETSETTTSE-------SAAFI----------TGESPENTALQ- 911

  Fly  1206 PSSQPSSSQRSRGVTIAQMARHNLATSKPFIAHSLRLSIQQLASTQKRSIPPKTLVTHNTTKEPE 1270
                 ||||:|.        .:..:..||               ..:|...||   .|.||.:|.
 Worm   912 -----SSSQKSE--------ENESSAEKP---------------GARRDFVPK---KHKTTVKPA 945

  Fly  1271 DSEYYDSETSEQYTDEDNEVLDKTQPRAMSSTTVAAVLPAVPSTTTEREPQKTSSSPSPTKATSS 1335
            ::                     |...|.|:||..      |.||||             |:|:.
 Worm   946 ET---------------------TSAVAASTTTTE------PITTTE-------------KSTTL 970

  Fly  1336 TTTQPIETTTGDLEYDSSGSSDYVNDANDISSGVVNSLEARKNFLLSLLKQRLTQIERTEAKKPA 1400
            .|| |||.||.:   :.:|.: :|..| .:....:|:||.            |::|..|:..:|.
 Worm   971 ETT-PIEATTLN---EVTGPA-FVTGA-PVDETTINTLEL------------LSKINNTQISQPK 1017

  Fly  1401 TSTSTTTDAPKT------SSSSTSPASTTSESTSP---VTSSTARSSLTASKHLGPEALSRQKSL 1456
            .:..:.|||..:      .|.:.:|.:.|..:|:.   ||::.|..:..:.|.:..||
 Worm  1018 PTDISKTDALSSLISGLIGSFTKAPMAPTIHTTTDAAFVTATEASLNDGSDKKIIDEA------- 1075

  Fly  1457 TPQSAEYYDEDDDYMEDEPVGSSDAEKKEHGTVLISEKQAAATAKRHIAPPSAQPLRQAMLNILA 1521
                    ...|:....:|....|.|.:       .||:   ..::.|....|:.||:.  .:|.
 Worm  1076 --------QPTDEIRRAQPTNEMDKEME-------FEKR---IREQRIQMEQAKRLREE--ELLE 1120

  Fly  1522 TRSEENKVDLKTTSDGLQFRRFESSQIPTEGPPNRASIVVAEALSRRLADNVGEHLPGPTVPHTS 1586
            .:.:|.:::.|..::.::.::....|:...........|:.|  ..||.:...:.|    :....
 Worm  1121 KQLQEQEIEEKARNEMIERKQKMLQQLEELKEAEERQRVLLE--QERLQEQERQRL----IAEKE 1179

  Fly  1587 DAKAISSVSQTT------IRSRESQ-------TKSSSQTPPSISTETPATQAIQNHRTDEATQST 1638
            ...|..|:|.||      .|.|.:|       |:..:.|.||                 |..|..
 Worm  1180 AEIAFGSISTTTEASKFKYRLRPAQCAAINKFTRVFNITDPS-----------------EWIQKN 1227

  Fly  1639 LEIVTQTTPKSAPP 1652
            .|...:..|:::.|
 Worm  1228 CEFAKRYFPEASCP 1241

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mur2B	NP_001284789.1	ChtBD2	88..136	CDD:214696
		CBM_14	150..197	CDD:279884
		CBM_14	221..275	CDD:279884
dpy-6	NP_509435.2	GBP_C	<1089..1182	CDD:303769	17/110 (15%)
		coiled coil	1157..1166	CDD:293879	2/10 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000