Protein Alignment Mur2B and srap-1

DIOPT Version :9

• Sequence 1: NP_001284789.1
• Gene: Mur2B / 31111
• FlyBaseID: FBgn0025390
• Length: 1795
• Species: Drosophila melanogaster
• Sequence 2: NP_001364584.1
• Gene: srap-1 / 174709
• WormBaseID: WBGene00011522
• Length: 3532
• Species: Caenorhabditis elegans
• Alignment Length: 2088
• Identity: 449/2088 - (21%)
• Similarity: 712/2088 - (34%)
• Gaps: 625/2088 - (29%)

  Fly   172 TQPW------LFACPAGTIFSPVE------------------RKCLPGDQCPSTEISDSGSYIPQ 212
            |.||      |......|..||.|                  :.|:...|....|..:.....|.
 Worm   697 TNPWGETETPLSEGEKTTTSSPKEEAATLKTIGQEVDDDSLLKGCIVHFQSQPIEERNKEFTAPF 761

  Fly   213 NCELKFP-------ECAEEGTFRSPTD-----CALYYTCRLQESGTYLQTRFKCPGSNSFDLERK 265
            ...||.|       .|.::|...:..|     |:|.|           :.:..|......:::
 Worm   762 ELNLKVPTAEICAHRCYQDGCTAAKYDPSTQQCSLAY-----------EDKPFCGNGRLVNID-- 813

  Fly   266 LCRPRSE----VDCFDFVP-----------GPVQVPYAP--------------QPYYPPYPAAPP 301
                ||:    :.|...||           |.|.....|              :|...|. .||.
 Worm   814 ----RSDKTVWIHCLSCVPLKNSKPAENTDGEVTESNLPDGSGEHGADTASGEEPTSTPI-TAPT 873

  Fly   302 LYEEDDYDTGAREQQPALKSEKLQVAAEGFEKPSLNVVVLQTT---TLEPSTAYHKYPAYPSYPS 363
            .:..||..|.|..::....:     |.|...:.:....|.:.:   |..|:|.
 Worm   874 DFSNDDQVTEASGEETTTAA-----ATEASSEETTTSAVTEGSGEETTVPTTV------------ 921

  Fly   364 YEYSSHHRGKERAAENLELEKEGVPRKLKLSENIV-IQPETPATAATTREPLND----------- 416
                      |.:.|...|....||.:|...:.:. ...|...|||.|.....:
 Worm   922 ----------ESSGEEPALSSTSVPTELSKDDQVTEASGEETTTAAATEASSEETTTPAVTEASG 976

  Fly   417 -------INKYQYKRYTYGTDKNDVTEAPEIKSPLKGLHLSENIVIL----PETTTTTTTTTKPV 470
                   :.:...:..|..|......|.|.:.|......||::..:.    .||||...|.....
 Worm   977 EESTTSAVTEGSGEEITVPTTVESSGEEPALSSTSVPTELSKDDQVTEASGEETTTAAATEASSE 1041

  Fly   471 VLTCPTISPPDTTPKPSTTTAVTKST----------------PKISSTE---------------- 503
            ..|.|.::  :.:.:.|||:|||:.:                |.||||.
 Worm  1042 ETTTPAVT--EASGEESTTSAVTEGSGEEITVHTTVESSGEEPAISSTSIPTELSKDDQVTEASG 1104

  Fly   504 QHSTTTAKTTTTKRPTT---VTE------KTSSATEK--PRTTVVTTT-----TQKRSTTTHNT- 551
            :.:||.|.|..:...||   |||      .||:.||:  ..||||...     .|..|:|:..|
 Worm  1105 EETTTAAATEASLEATTTPAVTEASGEEITTSAVTEESGEETTVVAVVESSGEEQASSSTSIPTE 1169

  Fly   552 ----------SPDTKTTIRSTTLSPKTTTTPSTTTPS---TTTPSTTTPSTTTP---STTTPS-- 598
                      |.:..||..:|..|.:.||||:.|..|   ||..:....|...|   ||:.|:
 Worm  1170 LSKDDQVTEASGEETTTAAATEASSEATTTPAVTEASGEETTVVAVVESSGEEPASSSTSIPTEL 1234

  Fly   599 -------------TTTPSTT------TTVKVSTHRPRTTSQKTTTASTTT---KKTTTSPKTTKT 641
                         |.|.:.|      ||...:|   .|:|::||.::.|.   ::||.......:
 Worm  1235 SKDNQVTEASGEETNTAAVTEGSGEETTTAAAT---ETSSEETTISAVTEASGEETTVVAVVQSS 1296

  Fly   642 TDIPTSTTSKLSTTTQKTTTTTHKFTAATTSTEKPKTTTEKTSTVSTTTKKSTE---------SS 697
            .:.|.|:::.:.|...|....|......||:....:.::|:|:|::.|.....|         |.
 Worm  1297 GEEPASSSTSIPTELSKDDQVTEASGEETTTAAATEASSEETTTLAVTEGSGEETTVVAVVESSG 1361

  Fly   698 PKP-TSSTGKPTTTPKPSTRTTPTTTKVTTTTQIT------TTTP--LRSSTETTSTQPPTTTTP 753
            .:| :|||..||...| ..:.|..:.:.|||..:|      |.||  ..:|:|.|:|...|..:.
 Worm  1362 EEPASSSTSIPTELSK-DDQVTEASGEETTTAAVTEGSGEETVTPAATEASSEATTTPAGTEASG 1425

  Fly   754 QPTTTTTLT-----------------VTPKTSTTTTTTE----KPITSSPKPTTTTQKTTSTAPN 797
            :.|||:.:|                 ..|.:|:|:..||    ..:|......|||...|.|:..
 Worm  1426 EETTTSAVTEGSGEENTVVAVVESSGEEPASSSTSIPTELSNDDQVTEGSGEETTTAAATETSSE 1490

  Fly   798 TTKVAITTQ---KETTPT-------QSTSTTIFTRKTTTNNP----EPTSTEKPITSTTPKPS-- 846
            .|..::.|:   :|||.:       :.|:|:..|..:...|.    ..:|.|:|.:|:|..|:
 Worm  1491 ETTTSVVTEGSGEETTTSAVTEASGEETTTSAVTEGSGEENTVVAVVQSSGEEPASSSTSIPTEL 1555

  Fly   847 ------------TTTPKTSTVASSTEKTTISSPKPTTEKSTENPTTNSVK--------------- 884
                        .||...:|.|||.|.||    ...||.|.|..||::|.
 Worm  1556 SKDDQVTEASGEETTTAAATEASSEETTT----SAVTEGSGEETTTSAVSEGSGDETTTAAATEA 1616

  Fly   885 -------------------TSALT------SSTQRATSTTSEPTKTTQNIT------TTTPK--- 915
                               |||:|      ::|..||..:||.| .|..:|      |||..
 Worm  1617 SSEETITSAVTEGSGEETTTSAVTEGSGEETTTAAATEASSEET-ITSAVTEGSGEETTTSAVTE 1680

  Fly   916 --------PTTLKTSTQEATTSTQKVST-------VT------ITTKKATE-SSPLTTLST---- 954
                    |||:::|.:|...|:..:.|       ||      .||..||| ||..||.|.
 Worm  1681 GSGEEITVPTTVESSGEEPALSSMSIPTELSKDDQVTEASGEETTTAAATETSSEETTTSVVTEG 1745

  Fly   955 ---------------EEP----NTTPKPL------------RTTTPTTTSVTATTRITTTTISES 988
                           |||    .:.|..|            .|||...|..::...||:.....|
 Worm  1746 SGEQTTVVAVVESSGEEPASSSTSIPTELSKDDQVTEASGEETTTAAATEASSEETITSAVTEGS 1810

  Fly   989 STETT-------STQKPKSTT---PT------STTRTTPKVTTVIVSTQ--NPTTTTS------- 1028
            ..|||       |.::|.|::   ||      ..|..:.:.||...:|:  :..||||
 Worm  1811 GEETTVVAVVESSGEEPASSSTSVPTELSKDDQVTEASGEETTTAAATEASSEETTTSAVTEGSG 1875

  Fly  1029 ---KTSTVT------ITTPNPSPSTQRPTTTTR------QPTSITASTTSIG------TTRIPTT 1072
               .||.||      .|||..:.::...|||:.      :.|::.|...|.|      :|.|||.
 Worm  1876 EETTTSAVTEASSEATTTPAGTEASGEETTTSAVTEGSGEETTVVAVVESSGEEPASSSTSIPTE 1940

  Fly  1073 TNPQNS-TSSTDLTTVTRPPCPDPDSTSDKNTNTACT----QELQQVNLLELQSPQ--------- 1123
            .:..:. |.::...|:|..    ....|::.|.:|.|    ::...|.::||...|
 Worm  1941 LSKNDQVTEASGEETITAA----ATEASEETTTSAVTEGSGEDTTVVAVVELSGEQPASSSTSIP 2001

  Fly  1124 ----KQEQFT-----HTRTHTALTGSRNTL-------GGQE-----VPDYMDDAPSSAE------ 1161
                |.:|.|     .|.|..|...|..|.       .|:|     |.:...:.|:|:.
 Worm  2002 TELSKDDQVTEASGEETTTAAATEASEETTTSAVTEGSGEETTVVAVVESSGEEPASSSTSIPTE 2066

  Fly  1162 -AESGQATTAKAPTMSTLAAAHLLQKLFHIISTTPPSREH--------APTQRPSSQPSSSQRS- 1216
             ::..|.|.|.....:|.||....::     :||....|.        |..:....||:||..|
 Worm  2067 LSKDDQVTEASGEETTTAAATEASEE-----TTTSAVTEGSGEDTTVVAVVESSGEQPASSSTSI 2126

  Fly  1217 ---------------RGVTIAQMARHNLATSKPFIAHSLRLSIQQLASTQKRSIPPKTLVTHNTT 1266
                           ...|.|.....:..|:...:..........:|..:.....|.:..|...|
 Worm  2127 PTELSKDDQVTEASGEETTTAAATEASEETTTSAVTEGSGEDTTVVAVVESSGEQPASSSTSIPT 2191

  Fly  1267 KEPEDSEYYDSETSEQYTDEDNEVLDKTQPRAMS-----STTVAAVL------PAVPSTTTEREP 1320
            :..:|.:..::...|..|....|..::|...|::     .|||.||:      ||..||:...|.
 Worm  2192 ELSKDDQVTEASGEETTTAAATEASEETTTSAVTEGSGEETTVVAVVESSGEEPASSSTSIPTEL 2256

  Fly  1321 QK----TSSSPSPTKATSSTTTQPIETTTGDLEYDSSGSSDYV------NDANDISSGVVNSLEA 1375
            .|    |.:|...|...::|.....||||..:. :.||....|      :|....||......|.
 Worm  2257 SKDDKVTEASGEETTTAAATDASSEETTTSAVT-EGSGEETTVVAVVESSDEEPASSSTSIPTEL 2320

  Fly  1376 RKNFLLSLLKQRLTQIERTEAKKPATSTSTTTDA-PKTSSSSTSPASTTSESTSPVTSSTARSSL 1439
            .|:          .|:  |||....|:|:..|:| .:|::|:.:..|....:...|..|:.....
 Worm  2321 SKD----------DQV--TEASGEETTTAAATEASEETTTSAVTEGSGEETTVVAVVESSGEEPA 2373

  Fly  1440 TASKHLGPEALSRQKSLTPQSAEYYDEDDDYMEDEPVGSSDAEKKEHGTVLISEKQAAATAKRHI 1504
            ::|..: |..||:...:|..|.|         |.....::||..:|..|..::|.....|....:
 Worm  2374 SSSTSI-PTELSKDDKVTEASGE---------ETTTAAATDASSEETTTSAVTEGSGEETTVVAV 2428

  Fly  1505 APPSAQPLRQAMLNILATRSEENKV-----DLKTTSDGLQFRRFESSQIPTEGPPNRASIV-VAE 1563
            ...|.:....:..:|....|::::|     :..||:...:.....::...|||.....::| |.|
 Worm  2429 VESSDEEPASSSTSIPTELSKDDQVTEASGEETTTAAATEASEETTTSAVTEGSGEETTVVAVVE 2493

  Fly  1564 A---------------LSR--RLADNVGEHLPGPTVPHTSDAKAISSVSQ-----TTI-----RS 1601
            :               ||:  ::.:..||..........|:....|:|::     ||:     .|
 Worm  2494 SSGEEPASSSTSIPTELSKDDQVTEASGEETTTAAATEASEETTTSAVTEGSGEDTTVVAVVESS 2558

  Fly  1602 RESQTKSSSQTPPSISTETPATQAI-QNHRTDEATQSTLEIVTQTTPKSAPPATAVPVAV----R 1661
            .|....||:..|..:|.:...|:|. :...|..||:::.|..|....:.:...|.|...|    .
 Worm  2559 GEQPASSSTSIPTELSKDDQVTEASGEETTTAAATEASEETTTSAVTEGSGEETTVVAVVESSGE 2623

  Fly  1662 QEVLSVNSRPWLLAARNQ----------TVHLTPISSIAARAPSNPVSHANRSINPLVS--SPED 1714
            :...|..|.|..|:..:|          |...|..||......:........:....|:  |.|:
 Worm  2624 EPASSSTSIPTELSKDDQVTEASGEETTTAAATEASSEETTTSAVTEGSGEETTTSAVTEGSGEE 2688

  Fly  1715 HSTEKVPQ 1722
            .:|..||:
 Worm  2689 TTTSAVPE 2696

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mur2B	NP_001284789.1	ChtBD2	88..136	CDD:214696
		CBM_14	150..197	CDD:279884	9/48 (19%)
		CBM_14	221..275	CDD:279884	9/62 (15%)
srap-1	NP_001364584.1	PRK13108	<1876..2013	CDD:237284	32/140 (23%)
		PAN_APPLE	<3374..3413	CDD:412169

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000