DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment inc and KCTD17

DIOPT Version :9

Sequence 1:	NP_001284786.1	Gene:	inc / 31110	FlyBaseID:	FBgn0025394	Length:	211	Species:	Drosophila melanogaster
Sequence 2:	XP_011528676.1	Gene:	KCTD17 / 79734	HGNCID:	25705	Length:	370	Species:	Homo sapiens

Alignment Length:	172	Identity:	108/172 - (62%)
Similarity:	134/172 - (77%)	Gaps:	4/172 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 GTDQWVKLNVGGTYFLTTKTTLSRDPNSFLSRLIQEDCDLISDRDETGAYLIDRDPKYFAPVLNY 83
            |..:||:||||||.||||:.||.|:..||||||.|.: :|.|||||||||||||||.||.|:||:
Human    28 GWGKWVRLNVGGTVFLTTRQTLCREQKSFLSRLCQGE-ELQSDRDETGAYLIDRDPTYFGPILNF 91

  Fly    84 LRHGKLVLD-GVSEEGVLEEAEFYNVTQLIALLKECILHRDQR-PQTDKKRVYRVLQCREQELTQ 146
            ||||||||| .::||||||||||||:..||.::|:.:..:|.. .|...|.|||||||:|:||||
Human    92 LRHGKLVLDKDMAEEGVLEEAEFYNIGPLIRIIKDRMEEKDYTVTQVPPKHVYRVLQCQEEELTQ 156

  Fly   147 MISTLSDGWRFEQLISMQYT-NYGPFENNEFLCVVSKECGTT 187
            |:||:|||||||||:::..: |||..:..|||||||||..:|
Human   157 MVSTMSDGWRFEQLVNIGSSYNYGSEDQAEFLCVVSKELHST 198

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
inc	NP_001284786.1	BTB	23..122	CDD:197585	67/99 (68%)
inc	NP_001284786.1	BTB_2	24..112	CDD:280393	63/88 (72%)
KCTD17	XP_011528676.1	BTB	32..131	CDD:197585	67/99 (68%)
KCTD17	XP_011528676.1	BTB_2	33..121	CDD:280393	63/88 (72%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165145622
Domainoid	1	1.000	137	1.000	Domainoid score	I4894
eggNOG	1	0.900	-	-		E1_KOG2715
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	237	1.000	Inparanoid score	I3380
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1333587at2759
OrthoFinder	1	1.000	-	-		FOG0001778
OrthoInspector	1	1.000	-	-		otm40345
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR14958
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1131
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	13	12.860