DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment inc and kctd2

DIOPT Version :9

Sequence 1:	NP_001284786.1	Gene:	inc / 31110	FlyBaseID:	FBgn0025394	Length:	211	Species:	Drosophila melanogaster
Sequence 2:	NP_001038899.1	Gene:	kctd2 / 751724	ZFINID:	ZDB-GENE-060825-85	Length:	267	Species:	Danio rerio

Alignment Length:	204	Identity:	125/204 - (61%)
Similarity:	159/204 - (77%)	Gaps:	9/204 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 SPNVLKKQGTDQWVKLNVGGTYFLTTKTTLSRDPNSFLSRLIQEDCDLISDRDETGAYLIDRDPK 75
            ||...:|.|: :||:||||||||:|||.||.|||.|||.||.|||.||.||:||||||||||||.
Zfish    67 SPEATEKPGS-RWVRLNVGGTYFVTTKQTLCRDPKSFLYRLCQEDPDLDSDKDETGAYLIDRDPT 130

  Fly    76 YFAPVLNYLRHGKLVLD-GVSEEGVLEEAEFYNVTQLIALLKECILHRDQRPQTDK---KRVYRV 136
            ||.|:|||||||||::: .::||||||||||||:..|:.|:||.|  ||...:|.:   |.||||
Zfish   131 YFGPILNYLRHGKLIINKNLAEEGVLEEAEFYNIASLVRLVKERI--RDNENRTSQGPVKHVYRV 193

  Fly   137 LQCREQELTQMISTLSDGWRFEQLISMQYT-NYGPFENNEFLCVVSKEC-GTTAGRELELNDRAK 199
            |||:|:|||||:||:||||:||||||:..: |||..:..|||||||:|. .:|.|..:|..::||
Zfish   194 LQCQEEELTQMVSTMSDGWKFEQLISIGSSYNYGNEDQAEFLCVVSRELNNSTNGIVIEPTEKAK 258

  Fly   200 VLQQKGSRI 208
            :||::|||:
Zfish   259 ILQERGSRM 267

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
inc	NP_001284786.1	BTB	23..122	CDD:197585	71/99 (72%)
inc	NP_001284786.1	BTB_2	24..112	CDD:280393	65/88 (74%)
kctd2	NP_001038899.1	BTB	78..179	CDD:197585	73/102 (72%)
kctd2	NP_001038899.1	BTB_2	79..167	CDD:280393	65/87 (75%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170579013
Domainoid	1	1.000	141	1.000	Domainoid score	I4648
eggNOG	1	0.900	-	-		E1_KOG2715
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	240	1.000	Inparanoid score	I3315
OMA	1	1.010	-	-		QHG48084
OrthoDB	1	1.010	-	-		D1333587at2759
OrthoFinder	1	1.000	-	-		FOG0001778
OrthoInspector	1	1.000	-	-		otm25396
orthoMCL	1	0.900	-	-		OOG6_106132
Panther	1	1.100	-	-	O	PTHR14958
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1131
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	15	14.770