DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment inc and KCTD9

DIOPT Version :9

Sequence 1:	NP_001284786.1	Gene:	inc / 31110	FlyBaseID:	FBgn0025394	Length:	211	Species:	Drosophila melanogaster
Sequence 2:	NP_060104.2	Gene:	KCTD9 / 54793	HGNCID:	22401	Length:	389	Species:	Homo sapiens

Alignment Length:	250	Identity:	76/250 - (30%)
Similarity:	115/250 - (46%)	Gaps:	52/250 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 KSPNVLKKQGTDQWVKLNVGGTYFLTTKTTL-SRDPNSFLSRLIQEDCDLISDRDETGAYLIDRD 73
            |.|..|....|| |:.|||||.||.||::|| :::|:|.|:.:.::.....:.:|..||:||||.
Human    78 KPPEGLLGFHTD-WLTLNVGGRYFTTTRSTLVNKEPDSMLAHMFKDKGVWGNKQDHRGAFLIDRS 141

  Fly    74 PKYFAPVLNYLRHGKLVL-DGVSEEGVLEEAEFYNVTQLIALLKECILHRDQRPQTDKKRVYRVL 137
            |:||.|:|||||||:|:: ||::..||||||.|:.:..||..|:..|  ::.:|..|...:.|..
Human   142 PEYFEPILNYLRHGQLIVNDGINLLGVLEEARFFGIDSLIEHLEVAI--KNSQPPEDHSPISRKE 204

  Fly   138 QCREQELTQMISTL-SDGWRFE----QLISMQYTNYGPFEN-------NEFLCVVSKE------- 183
            ..|....|...|.| ..|..|.    ..:.::|.|: ...|       :..||..:.|
Human   205 FVRFLLATPTKSELRCQGLNFSGADLSRLDLRYINF-KMANLSRCNLAHANLCCANLERADLSGS 268

  Fly   184 -------------CGTTAGRELEL--------------NDRAKVLQQKGSRILGI 211
                         |....|..|:|              ....|.:..:||::.||
Human   269 VLDCANLQGVKMLCSNAEGASLKLCNFEDPSGLKANLEGANLKGVDMEGSQMTGI 323

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
inc	NP_001284786.1	BTB	23..122	CDD:197585	47/100 (47%)
inc	NP_001284786.1	BTB_2	24..112	CDD:280393	42/89 (47%)
KCTD9	NP_060104.2	KHA	2..66	CDD:340593
		BTB_POZ_KCTD9	89..188	CDD:349677	47/99 (47%)
		YjbI	168..378	CDD:224276	33/158 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D545341at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920