DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment inc and KCTD5

DIOPT Version :9

Sequence 1:	NP_001284786.1	Gene:	inc / 31110	FlyBaseID:	FBgn0025394	Length:	211	Species:	Drosophila melanogaster
Sequence 2:	NP_061865.1	Gene:	KCTD5 / 54442	HGNCID:	21423	Length:	234	Species:	Homo sapiens

Alignment Length:	191	Identity:	123/191 - (64%)
Similarity:	151/191 - (79%)	Gaps:	4/191 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 QWVKLNVGGTYFLTTKTTLSRDPNSFLSRLIQEDCDLISDRDETGAYLIDRDPKYFAPVLNYLRH 86
            :||:|||||||||||:.||.|||.|||.||.|.|.||.||:||||||||||||.||.||||||||
Human    44 KWVRLNVGGTYFLTTRQTLCRDPKSFLYRLCQADPDLDSDKDETGAYLIDRDPTYFGPVLNYLRH 108

  Fly    87 GKLVLD-GVSEEGVLEEAEFYNVTQLIALLKECILHRDQR-PQTDKKRVYRVLQCREQELTQMIS 149
            ||||:: .::||||||||||||:|.||.|:|:.|..||.: .|...|.|||||||:|:|||||:|
Human   109 GKLVINKDLAEEGVLEEAEFYNITSLIKLVKDKIRERDSKTSQVPVKHVYRVLQCQEEELTQMVS 173

  Fly   150 TLSDGWRFEQLISMQYT-NYGPFENNEFLCVVSKEC-GTTAGRELELNDRAKVLQQKGSRI 208
            |:||||:||||:|:..: |||..:..|||||||||. .|..|...|.:::||:||::|||:
Human   174 TMSDGWKFEQLVSIGSSYNYGNEDQAEFLCVVSKELHNTPYGTASEPSEKAKILQERGSRM 234

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
inc	NP_001284786.1	BTB	23..122	CDD:197585	73/99 (74%)
inc	NP_001284786.1	BTB_2	24..112	CDD:280393	67/88 (76%)
KCTD5	NP_061865.1	BTB_POZ_KCTD5	40..151	CDD:349698	75/106 (71%)
KCTD5	NP_061865.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	213..234		8/20 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165145621
Domainoid	1	1.000	137	1.000	Domainoid score	I4894
eggNOG	1	0.900	-	-		E1_KOG2715
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H10363
Inparanoid	1	1.050	237	1.000	Inparanoid score	I3380
Isobase	1	0.950	-	0	Normalized mean entropy	S2734
OMA	1	1.010	-	-		QHG48084
OrthoDB	1	1.010	-	-		D1333587at2759
OrthoFinder	1	1.000	-	-		FOG0001778
OrthoInspector	1	1.000	-	-		otm40345
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR14958
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3727
SonicParanoid	1	1.000	-	-		X1131
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	16	15.850