DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment inc and kctd9a

DIOPT Version :9

Sequence 1:	NP_001284786.1	Gene:	inc / 31110	FlyBaseID:	FBgn0025394	Length:	211	Species:	Drosophila melanogaster
Sequence 2:	NP_001013585.2	Gene:	kctd9a / 541442	ZFINID:	ZDB-GENE-050320-147	Length:	389	Species:	Danio rerio

Alignment Length:	215	Identity:	69/215 - (32%)
Similarity:	109/215 - (50%)	Gaps:	47/215 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 TDQWVKLNVGGTYFLTTKTTL-SRDPNSFLSRLIQEDCDLISDRDETGAYLIDRDPKYFAPVLNY 83
            || |:.||:||..|.||::|| |::|:|.|:.:.:|.....:.:||.||:||||.|:||.|:|||
Zfish    88 TD-WLTLNIGGRLFTTTRSTLVSKEPDSMLAHMFREKDVWGNKQDERGAFLIDRSPEYFEPILNY 151

  Fly    84 LRHGKLVL-DGVSEEGVLEEAEFYNVTQLIALLKECILHRDQRPQTD-----KKRVYRVL----- 137
            ||||:::: ||::..||||||.|:.:.||...|:..|  ::..|..|     :|...|.|
Zfish   152 LRHGQIIINDGINLLGVLEEARFFGIEQLAEQLEVAI--KNSHPPEDHSPLSRKEFVRFLLATPT 214

  Fly   138 --QCREQELTQMISTLSDGWRFEQLISMQYTNYG---------PFENNEFLCVVSKECGTTAGRE 191
              :.|.|.|....:.||       .:.::|.|:.         .:.|   ||..:.|....:|..
Zfish   215 KSELRCQGLNFSGADLS-------RLDLRYINFKMANLSRCNLTYAN---LCCSNLERADLSGAN 269

  Fly   192 LELNDRAKVLQQKGSRILGI 211
            |:           |:.:.|:
Zfish   270 LD-----------GANLQGV 278

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
inc	NP_001284786.1	BTB	23..122	CDD:197585	47/100 (47%)
inc	NP_001284786.1	BTB_2	24..112	CDD:280393	43/89 (48%)
kctd9a	NP_001013585.2	KHA	2..64	CDD:288667
		BTB	90..192	CDD:197585	47/103 (46%)
		BTB	91..181	CDD:295341	43/89 (48%)
		Pentapeptide	219..251	CDD:279183	7/38 (18%)
		Pentapeptide_4	224..310	CDD:290330	12/76 (16%)
		Pentapeptide	243..280	CDD:279183	8/50 (16%)
		Pentapeptide	303..342	CDD:279183
		Pentapeptide_4	310..384	CDD:290330
		Pentapeptide	338..377	CDD:279183
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D545341at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920