DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment inc and Kctd2

DIOPT Version :9

Sequence 1:	NP_001284786.1	Gene:	inc / 31110	FlyBaseID:	FBgn0025394	Length:	211	Species:	Drosophila melanogaster
Sequence 2:	XP_008766633.1	Gene:	Kctd2 / 498024	RGDID:	1566063	Length:	263	Species:	Rattus norvegicus

Alignment Length:	197	Identity:	119/197 - (60%)
Similarity:	154/197 - (78%)	Gaps:	9/197 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 GTDQWVKLNVGGTYFLTTKTTLSRDPNSFLSRL-IQEDCDLISDRDETGAYLIDRDPKYFAPVLN 82
            |..:||:||||||||:||:.||.|:|.|||.|| .|||.:|.||:||||||||||||.||.|:||
  Rat    69 GAARWVRLNVGGTYFVTTRQTLGREPKSFLCRLCCQEDPELDSDKDETGAYLIDRDPTYFGPILN 133

  Fly    83 YLRHGKLVL-DGVSEEGVLEEAEFYNVTQLIALLKECILHRDQRPQTDK---KRVYRVLQCREQE 143
            |||||||:: ..::||||||||||||:..|:.|:||.|  ||...:|.:   |.|||||||:|:|
  Rat   134 YLRHGKLIITKELAEEGVLEEAEFYNIASLVRLVKERI--RDNENRTSQGPVKHVYRVLQCQEEE 196

  Fly   144 LTQMISTLSDGWRFEQLISMQYT-NYGPFENNEFLCVVSKEC-GTTAGRELELNDRAKVLQQKGS 206
            ||||:||:||||:||||||:..: |||..:..|||||||:|. .:|.|..:|.:::||:||::||
  Rat   197 LTQMVSTMSDGWKFEQLISIGSSYNYGNEDQAEFLCVVSRELNNSTNGIVIEPSEKAKILQERGS 261

  Fly   207 RI 208
            |:
  Rat   262 RM 263

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
inc	NP_001284786.1	BTB	23..122	CDD:197585	68/100 (68%)
inc	NP_001284786.1	BTB_2	24..112	CDD:280393	62/89 (70%)
Kctd2	XP_008766633.1	BTB	73..175	CDD:197585	70/103 (68%)
Kctd2	XP_008766633.1	BTB_2	74..163	CDD:280393	62/88 (70%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166339314
Domainoid	1	1.000	137	1.000	Domainoid score	I4759
eggNOG	1	0.900	-	-		E1_KOG2715
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	239	1.000	Inparanoid score	I3274
OMA	1	1.010	-	-		QHG48084
OrthoDB	1	1.010	-	-		D1333587at2759
OrthoFinder	1	1.000	-	-		FOG0001778
OrthoInspector	1	1.000	-	-		otm44475
orthoMCL	1	0.900	-	-		OOG6_106132
Panther	1	1.100	-	-	O	PTHR14958
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1131
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	13	12.810