DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment inc and Kctd5

DIOPT Version :9

Sequence 1:	NP_001284786.1	Gene:	inc / 31110	FlyBaseID:	FBgn0025394	Length:	211	Species:	Drosophila melanogaster
Sequence 2:	NP_001099238.1	Gene:	Kctd5 / 287109	RGDID:	1304990	Length:	234	Species:	Rattus norvegicus

Alignment Length:	197	Identity:	124/197 - (62%)
Similarity:	153/197 - (77%)	Gaps:	4/197 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 KKQGTDQWVKLNVGGTYFLTTKTTLSRDPNSFLSRLIQEDCDLISDRDETGAYLIDRDPKYFAPV 80
            :..|..:||:|||||||||||:.||.|||.|||.||.|.|.||.||:||||||||||||.||.||
  Rat    38 RPSGVSKWVRLNVGGTYFLTTRQTLCRDPKSFLYRLCQADPDLDSDKDETGAYLIDRDPTYFGPV 102

  Fly    81 LNYLRHGKLVLD-GVSEEGVLEEAEFYNVTQLIALLKECILHRDQR-PQTDKKRVYRVLQCREQE 143
            ||||||||||:: .::||||||||||||:|.||.|:|:.|..||.: .|...|.|||||||:|:|
  Rat   103 LNYLRHGKLVINRDLAEEGVLEEAEFYNITSLIKLVKDKIRERDSKTSQMPVKHVYRVLQCQEEE 167

  Fly   144 LTQMISTLSDGWRFEQLISMQYT-NYGPFENNEFLCVVSKEC-GTTAGRELELNDRAKVLQQKGS 206
            ||||:||:||||:||||:|:..: |||..:..|||||||||. .|..|...|.:::||:||::||
  Rat   168 LTQMVSTMSDGWKFEQLVSIGSSYNYGNEDQAEFLCVVSKELHNTPYGTTSEPSEKAKILQERGS 232

  Fly   207 RI 208
            |:
  Rat   233 RM 234

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
inc	NP_001284786.1	BTB	23..122	CDD:197585	73/99 (74%)
inc	NP_001284786.1	BTB_2	24..112	CDD:280393	67/88 (76%)
Kctd5	NP_001099238.1	BTB_POZ_KCTD5	40..151	CDD:349698	76/110 (69%)
Kctd5	NP_001099238.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	213..234		8/20 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166339312
Domainoid	1	1.000	137	1.000	Domainoid score	I4759
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H10363
Inparanoid	1	1.050	239	1.000	Inparanoid score	I3274
OMA	1	1.010	-	-		QHG48084
OrthoDB	1	1.010	-	-		D1333587at2759
OrthoFinder	1	1.000	-	-		FOG0001778
OrthoInspector	1	1.000	-	-		otm44475
orthoMCL	1	0.900	-	-		OOG6_106132
Panther	1	1.100	-	-	LDO	PTHR14958
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1131
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	13	12.910