Protein Alignment Nmdar2 and Ir7e

DIOPT Version :10

• Sequence 1: NP_001014714.1
• Gene: Nmdar2 / 31107
• FlyBaseID: FBgn0053513
• Length: 1083
• Species: Drosophila melanogaster
• Sequence 2: NP_001138176.1
• Gene: Ir7e / 7354417
• FlyBaseID: FBgn0259189
• Length: 608
• Species: Drosophila melanogaster
• Alignment Length: 881
• Identity: 148/881 - (16%)
• Similarity: 272/881 - (30%)
• Gaps: 340/881 - (38%)

  Fly   134 AKLTFLKDYSFEQKN-------------IHFDMMSLTPSPTAILSTLCKEFLRVNVSAILYMMNN 185
            |.|....|.|.||.|             :|..::|:|||   ::.|||   .|.|.:...|
  Fly     5 ALLNSYYDLSGEQMNHINEFVARAVLHVVHHYILSVTPS---LVLTLC---CRSNHTCNFY---- 59

  Fly   186 EQFGHSTASAQYFLQLAGYLGIPVISWNADNSGLERRASQSTLQLQLAPSIEHQSAAMLSILERY 250
                                       |...|.|.|....:.||:             :::|...
  Fly    60 ---------------------------NKMMSTLFREWGLAPLQI-------------VNVLRGV 84

  Fly   251 KWH------QFSVV-TSQIAGHDDFVQAVRERVAEMQEHFKFTILNSIVVTRTSDLMELVNSEAR 308
            .||      .|:|: |...|..::.......|.....||: |..|                 :||
  Fly    85 PWHPVPGRRHFNVIFTDSFAAFEEIRMEYYSREYNYNEHY-FIFL-----------------QAR 131

  Fly   309 VMLLYATQTEAITILRAAEEMKLTGENYVW---VVSQSV-IEKKDA----HSQFPVGMLGVHFDT 365
            ..||..             ||:|..: |.|   ::..|: ::|.:.    :|.:|.|..|.  ..
  Fly   132 DRLLQG-------------EMRLIFD-YCWRYRLIHCSIQVQKSNGDILFYSYYPFGEHGC--SD 180

  Fly   366 SSAALMNEISNAIKIYSYGVEAYLTDPANRDRRLTTQSLSCEDEGRGRWDNGEIFFKYLRNVSIE 430
            ....|:|..:.::          |.:|                         ::|.:.|||.
  Fly   181 MEPQLINRYNGSM----------LVEP-------------------------DLFPRKLRNF--- 207

  Fly   431 GDLNKPNIEFTADGDLRSAELKIMNLRPSANNKNLVWEEIGVWKSWETQKLDIRDIAWPGNSHAP 495
              ...|         ||.|                :|:
  Fly   208 --FGCP---------LRCA----------------LWD--------------------------- 218

  Fly   496 PQGVPEKFHLKITFLEEAPYINLSPADPVSGKCLMDRGVLCRVAADHEMAADIDVGQAHRNESFY 560
               ||             |::.|.                    .|.|....::.|...|
  Fly   219 ---VP-------------PFLTLD--------------------EDQEEVLRVNGGYEGR----- 242

  Fly   561 QCCSGFCIDLLEKFAEELGFTYELVRVEDGKWGTLENGKWNGLIADLVNR-KTDMVLTSLMINTE 624
                     ||...||::.||..:.:|.       .|.:...|  :::.| :.|:.|..:.....
  Fly   243 ---------LLLALAEKMNFTIAVRKVH-------VNMRDEAL--EMLRRDEVDLTLGGIRQTVA 289

  Fly   625 REAVVDFSEPFMET-GIAIVVAKRTGIISPTAFLEPFDTASWM-LVGIVAIQAATFMIFLFEWLS 687
            |..|...|..:.:| .:..|:|....:.|......|:....|| ::|:||:.|...:|.
  Fly   290 RGMVATSSHNYHQTREVFGVLASSYELSSFDILFYPYRLQIWMGILGVVALSALIQLIV------ 348

  Fly   688 PSGYDMKLYLQNTNVTPYRFSLFRTYWLVWAVLFQAAVHVDSPRGFTSRFMTNVWALFAVVFLAI 752
              |..:            |..:...:||...::|.....::.||..|:|....:..::.::...|
  Fly   349 --GRML------------RERMGSRFWLNLELVFVGMPLLECPRSHTARLYCVMLMMYTLIIRTI 399

  Fly   753 YTANLAAFMITREEFHEFSGLNDSRLVHPFS------------HKPSFKFGTIPYSHTDSTIHK- 804
            | ..|...:|...:.:.:....:|.:...|:            ..||.:.........:|.:..
  Fly   400 Y-QGLLYHLIRTHQLNRWPQTIESLVQKNFTVVLTPIVQEVLDEIPSVQHMRFRLLEANSELDPL 463

  Fly   805 YFNVMHNYMRQYNKTSVADGVAAVLNGNLDSFIY--------------DGTVLDYLVAQDEDCRL 855
            ||...::.:||:...|.           ||.||:              .|:...:.:..::...:
  Fly   464 YFLEANHQLRQHVTASA-----------LDIFIHFNRLSADKVHQRGEQGSGAHFEIVPEDIISM 517

  Fly   856 MTVGSWYAMTGYGLAFSRNSKYVQMFNKRLLEFRANGDLERLRRYWMTGTCRPGKQEHKSSDPLA 920
            .       :|.|   .:::|..:...|:.::..|:.|.|....|:.::.:....:|   |...|.
  Fly   518 Q-------LTMY---LAKHSFLIDQLNEEIMWMRSVGLLSVWSRWELSESYLRNEQ---SFQVLG 569

  Fly   921 LEQFLSAFLLLMAGILLAALLLLLEHVYFK--YIRK 954
            ..:..:.||:::.|:::..|:.:||.|..:  |:||
  Fly   570 TMELYAIFLMVLVGLIVGLLVFILELVSMRSIYLRK 605

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nmdar2	NP_001014714.1	PBP1_iGluR_NMDA_NR2	99..485	CDD:380601	64/378 (17%)
		PBP2_iGluR_NMDA_Nr2	502..908	CDD:270436	69/435 (16%)
Ir7e	NP_001138176.1	Periplasmic_Binding_Protein_Type_2	218..>313	CDD:473866	26/180 (14%)