DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Nmdar2 and Ir94d

DIOPT Version :9

Sequence 1:	NP_001014714.1	Gene:	Nmdar2 / 31107	FlyBaseID:	FBgn0053513	Length:	1083	Species:	Drosophila melanogaster
Sequence 2:	NP_001138099.1	Gene:	Ir94d / 7354412	FlyBaseID:	FBgn0259193	Length:	593	Species:	Drosophila melanogaster

Alignment Length:	393	Identity:	78/393 - (19%)
Similarity:	130/393 - (33%)	Gaps:	125/393 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   634 PFMETGIA----IVVAKRTGIIS----------P-TAFLEPFDTASWMLVGIVAIQAATFMIFLF 683
            ||.|:.|:    ::.:.:.|.:.          | |.:..|.:..||.|:..|..:.....::..
  Fly   230 PFDESAISPARDLIASVQNGSVQIALGAIYPQVPYTGYSYPIELMSWCLMMPVPEEVPHSQLYSM 294

  Fly   684 EWLSPSGY--------------DMKLYLQNTNVTPYRFSLFRTYWLVWAVLFQAAVHVDSPRGFT 734
            .: ||..:              .|.|.|..     ||.| |..|:|          |....||..
  Fly   295 VF-SPMAFGITIVAMVLISLTLSMALRLHG-----YRVS-FSEYFL----------HDSCLRGVL 342

  Fly   735 SRFMTNVW---ALFAVVFLAI----------YTANLAAFMITREEFHEFSGLNDSRLVHPFSH-- 784
            |:....|.   ||...::|.|          |.:..:.|:.:...|.:.:.....|      |
  Fly   343 SQSFYEVLRAPALIKAMYLVICLLGLLITSWYNSYFSTFVTSAPRFPQLTSYESIR------HSN 401

  Fly   785 ------KPSF-----------KFGTIPYSHTDST----IHKYFNVMHNYMRQYNKTSVADGVAAV 828
                  ||.:           |:.:|.....|..    :...|:..:.||....|.|:......|
  Fly   402 IKIVIWKPEYEMLLFFSENMEKYSSIFQLQEDYKEFLHLRDSFDTRYGYMMPMEKWSLMKEQQRV 466

  Fly   829 LNGNLDSFIYDGTVLDYLVAQDEDCRLMTVGSWYAMTGYGLAFSRNSKYVQMFNKRLLEFRANGD 893
            .:..|.|.            ||:.|...||...:.|.       :||.:.:.|::.:|:..|.|.
  Fly   467 FSSPLFSL------------QDDLCVFHTVPIVFPMV-------KNSIFKEPFDRLILDVTATGL 512

  Fly   894 LERLRRYWMTGTCRPGK------------QEHKSSDPLALEQFLSAFLLLMAGILLAALLLLLEH 946
            |.|.|....|...:.|:            :..|..|.:.:.:|:.    .|.|  ||.::.|||.
  Fly   513 LSRWRDMSFTEMIKAGQLGLEDRGHPKEFRAMKVGDLIQIWRFVG----WMLG--LATIVFLLEL 571

  Fly   947 VYF 949
            :.|
  Fly   572 ICF 574

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Nmdar2	NP_001014714.1	PBP1_iGluR_NMDA_NR2	99..490	CDD:107373
		PBP2_iGluR_NMDA_Nr2	502..908	CDD:270436	66/338 (20%)
		Lig_chan	665..928	CDD:278489	61/324 (19%)
Ir94d	NP_001138099.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45463094
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930