Protein Alignment Nmdar2 and Ekar

DIOPT Version :9

• Sequence 1: NP_001014714.1
• Gene: Nmdar2 / 31107
• FlyBaseID: FBgn0053513
• Length: 1083
• Species: Drosophila melanogaster
• Sequence 2: NP_001036250.1
• Gene: Ekar / 43806
• FlyBaseID: FBgn0039916
• Length: 899
• Species: Drosophila melanogaster
• Alignment Length: 907
• Identity: 216/907 - (23%)
• Similarity: 362/907 - (39%)
• Gaps: 240/907 - (26%)

  Fly   141 DYSFEQKNIHFDMMSLTPSPTAILSTLCKEFLRVNVSAILYMMNNEQFGHSTASAQYFLQLAGYL 205
            ||..|..| .||...       .:..:|| .:||.|.|:....:       :..|.:...:...|
  Fly    62 DYYVEYVN-RFDSFE-------TVQKVCK-LIRVGVQAVFSPTD-------SVLATHINSICDAL 110

  Fly   206 GIPVISWNADNSGLERRASQSTLQLQLAPSIEHQSAAMLSILERYKWHQFSVVTSQIAG------ 264
            .||.|..:|.:           ..:.:.||.:..:.|...:::...|.:|.::..:..|
  Fly   111 DIPNIGRSAHD-----------FSINVYPSKQLVNYAFNDVIQYLNWTRFGILHEKENGIINLHQ 164

  Fly   265 ---------------HDDFVQAVRERVAEMQEHFKFTILNSIVVTRTSD---------LMELVNS 305
                           .|.:|.|:.|        ||...:::|::...|:         |.:.:|.
  Fly   165 LSRSFHGEVHMRQVSRDSYVSALNE--------FKGKEIHNIIIDTNSNGISILLKNILQQQMNE 221

  Fly   306 EARVMLLYATQTEAITILRAAEEMKLTGENYVWVVSQSVIEKKD-------------AHSQFPVG 357
            .....|..:...|...:    |:.|.   |:|.:.|..:::..|             :|..|...
  Fly   222 YKYHYLFTSFDLETYDL----EDFKY---NFVNITSFRLVDTADVGVKQILKDIGLYSHHIFKKP 279

  Fly   358 MLGVHFDTSS-----AALMNEISNAIKIYSYGVEAYLTDPANRDRRLTTQSLSCEDEGRGRWDNG 417
            .|.:|...|:     .|||   .:::.:::.|::.     ..:...||..::|||:|  ..||.|
  Fly   280 YLNLHIKKSTILESEPALM---FDSVYVFAIGLQT-----LEQSHSLTLLNISCEEE--NSWDGG 334

  Fly   418 EIFFKYLRNVSIEGDLNKPNIEFTADGDLRSAELKIMNLRPSANNKNLVWEEIGVWKSWETQKLD 482
            .....||..|..:| |..| |:| .||.....:|.::.|:..:..|      :|.|
  Fly   335 LSLINYLNAVEWKG-LTGP-IQF-KDGQRVQFKLDLIKLKQHSIVK------VGEW--------- 381

  Fly   483 IRDIAWPGNSHAPPQGVPEKFHLKIT----FLE--------------EAPYINLSPADPVSGKCL 529
                        .|.|     ||.||    |.:              |.||:.:......:|
  Fly   382 ------------TPHG-----HLNITEPSMFFDAGSMNVTLVVITILETPYVMMHYGKNFTG--- 426

  Fly   530 MDRGVLCRVAADHEMAADIDVGQAHRNESFYQCCSGFCIDLLEKFAEELGFTYELVRVEDGKWGT 594
                                      ||.||    |||:|:||..:.|:||.|.|..|.|.|:|.
  Fly   427 --------------------------NERFY----GFCVDILETISREVGFDYILDLVPDRKYGA 461

  Fly   595 L--ENGKWNGLIADLVNRKTDMVLTSLMINTEREAVVDFSEPFMETGIAIVVAKRTGIISPT--- 654
            .  |.|:|||::|.|:..|.|:.:.|:.|...||:|:||::|||..||:|:....|.  .||
  Fly   462 KDPETGEWNGMVAQLMKYKADLAVGSMTITYARESVIDFTKPFMNLGISILFKVPTS--EPTRLF 524

  Fly   655 AFLEPFDTASWMLVGIVAIQAATFMIFL------FEWLSPSGYDMKLYLQNTNVTPYRFSLFRTY 713
            :|:.|.....|:.| ::|....:..|::      .||...:..|    |:|.:: ..:|||..::
  Fly   525 SFMNPLAIEIWIYV-LIAYFLVSLCIYIVGKLSPIEWKCINACD----LENISI-GNQFSLTDSF 583

  Fly   714 WLVWAVLFQAAVHVDSPRGFTSRFMTNVWALFAVVFLAIYTANLAAFMITREEFHEFSGLNDSRL 778
            |.......|.:..: .||..::|.:::.|..|:::.:|.||||||||:.|            .|:
  Fly   584 WFTIGTFMQQSPDI-YPRAMSTRIISSTWGFFSLIIVASYTANLAAFLTT------------ERM 635

  Fly   779 VHPFSH------KPSFKFGTIPYSHT-----DSTIHKYFNV---MHNYMRQYNKTSVADGVAAVL 829
            ::|..:      :....:||:....|     ||.|..|..:   |.|.......|:..||:..|.
  Fly   636 INPIENAEDLASQTEISYGTLDSGSTMTFFRDSVIETYKKIWRSMDNKKPSAFTTTYEDGIKRVN 700

  Fly   830 NGNLDSFIYDGTVLDYLVAQDEDCRLMTVGSWYAMTGYGLAFSRNSKYVQMFNKRLLEFRANGDL 894
            .||. :|:.:.|:|||:|  ..||.|..:|......|||:|..:.|.:....:..:||.:..||:
  Fly   701 QGNY-AFLMESTMLDYIV--QRDCNLTQIGGLLDTKGYGIATPKGSPWRDKISLAILELQERGDI 762

  Fly   895 ERLRRYWMTG---TC-RPGKQEHKSSDPLALEQFLSAFLLLMAGILLAALLLLLEHVY-FKY 951
            :.|...|...   || |....:...::.|.||.....|::|:|||::||::...|..| |:|
  Fly   763 QMLYDKWWKNTDETCTRKNTSKQSKANSLGLESIGGVFVVLIAGIIVAAVVAFFEFWYNFRY 824

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nmdar2	NP_001014714.1	PBP1_iGluR_NMDA_NR2	99..490	CDD:107373	75/396 (19%)
		PBP2_iGluR_NMDA_Nr2	502..908	CDD:270436	124/452 (27%)
		Lig_chan	665..928	CDD:278489	73/286 (26%)
Ekar	NP_001036250.1	PBP1_iGluR_Kainate	24..388	CDD:107377	78/412 (19%)
		ANF_receptor	39..371	CDD:279440	71/363 (20%)
		PBP2_iGluR_Kainate	402..771	CDD:270432	117/425 (28%)
		Lig_chan	533..807	CDD:278489	76/295 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45463096
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR18966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840