Protein Alignment Nmdar2 and Grik

DIOPT Version :9

• Sequence 1: NP_001014714.1
• Gene: Nmdar2 / 31107
• FlyBaseID: FBgn0053513
• Length: 1083
• Species: Drosophila melanogaster
• Sequence 2: NP_001262788.1
• Gene: Grik / 42476
• FlyBaseID: FBgn0038840
• Length: 907
• Species: Drosophila melanogaster
• Alignment Length: 981
• Identity: 226/981 - (23%)
• Similarity: 379/981 - (38%)
• Gaps: 239/981 - (24%)

  Fly    50 KRILTPPSGPISLLLLTVLTLLILDTRSCQGLRLTNGGGSLSKGAAANKEQLNIGLIAPHTNFGK 114
            |.|.|..|.|:..    :||.|:|....|:|                  |:.|:||:..:|:
  Fly     5 KMISTEASFPLGF----ILTSLLLAFPGCRG------------------ERTNVGLVYENTD--- 44

  Fly   115 REYLRSINNAVTGLTKTRGAKLTFLKDYSFEQKNIHFDMMSLTPSPTAILS-TLCKEFLRVNVSA 178
            .:..:..:.|::...:..            |...:|...:|:.|..:...| .||| .||.|:.|
  Fly    45 PDLEKIFHLAISKANEEN------------EDLQLHGVSVSIEPGNSFETSKKLCK-MLRQNLVA 96

  Fly   179 ILYMMNNEQFG-HSTASAQYFLQLAGYLGIPVISWNADNSGLERRASQSTLQLQLAPSIEHQSAA 242
            :        || .|..:|::.:.:.....:|.:....|..     |...|:.|...|:.  ...|
  Fly    97 V--------FGPTSNLAARHAMSICDAKELPFLDTRWDFG-----AQLPTINLHPHPAT--LGVA 146

  Fly   243 MLSILERYKWHQFSV----------------------------------------VTSQIAGHDD 267
            :..::....|..|::                                        |..:|...||
  Fly   147 LRDMVVALGWESFTIIYESGEYLPTVRELLQMYGTAGPTVTVRRYELDLNGNYRNVLRRIRNADD 211

  Fly   268 FVQAVRERVAEMQEHFKFTILNSIVVTRTSDLMELV-NSEARVMLLYATQTEAITILRAAEEMKL 331
            |...|...:|.:.|.||......:|   |||...:: |.:...|.|...|.....|
  Fly   212 FSFVVVGSMATLPEFFKQAQQVGLV---TSDYRYIIGNLDWHTMDLEPYQHAGTNI--------- 264

  Fly   332 TGENYVWVVSQSVIEKKDA--HSQFPVGMLGVHFDTSSAALMNEISNAIKIYSYGVEAYLTDPAN 394
            ||...|...|:.|.|...|  .|:.|       |...|..|.|.::   .:|. ||:  |.....
  Fly   265 TGLRLVSPDSEQVQEVAKALYESEEP-------FQNVSCPLTNSMA---LVYD-GVQ--LLAETY 316

  Fly   395 RDRRLTTQSLSCEDEGRGRWDNGEIFFKYLRNVSIEGDLNKPNIEFTADGDLRSAELKIMNLRPS 459
            :.......:|||.|:  ..||.|.....|::::::.| |..| |.|..:|.....:|:::.|..|
  Fly   317 KHVNFRPVALSCNDD--SAWDKGYTLVNYMKSLTLNG-LTGP-IRFDYEGLRTDFKLEVIELAVS 377

  Fly   460 ANNKNLVWEEIGVWKSWETQKLDIRDIAWPGNSHAPP-QGVPEKFHLKITFLEEAPYINLSPADP 523
            ...|      ||.| |.|....:.|..  |.:|..|. :.:..|..:.||.:.| ||
  Fly   378 GMQK------IGQW-SGEDGFQENRPA--PAHSLEPDMRSLVNKSFVVITAISE-PY-------- 424

  Fly   524 VSGKCLMDRGVLCRVAADHEMAADIDVGQAHRNESFYQCCSGFCIDLLEKFAEELGFTYELVRVE 588
                     |:|...:...|           .|:.|    .||.|:|:::.:::|||:|.....|
  Fly   425 ---------GMLKETSEKLE-----------GNDQF----EGFGIELIDELSKKLGFSYTWRLQE 465

  Fly   589 DGKWGTLE--NGKWNGLIADLVNRKTDMVLTSLMINTEREAVVDFSEPFMETGIAIVVAKRTGII 651
            |.|:|.::  .|:|||::.::::.:.||.:|.|.:.:|||:.|||:.|||..||.|:.  |..:.
  Fly   466 DNKYGGIDPKTGEWNGMLREIIDSRADMGITDLTMTSERESGVDFTIPFMSLGIGILF--RKPMK 528

  Fly   652 SPT---AFLEPFDTASWMLVGIVAIQAATFMIFLFEWLSPSGYDMKLYLQNTNVTPY-------- 705
            .|.   :|:.||....|:.:|: |....:..:|:...|||:.:|          .||
  Fly   529 EPPKLFSFMSPFSGEVWLWLGL-AYMGVSISMFVLGRLSPAEWD----------NPYPCIEEPTE 582

  Fly   706 ---RFSLFRTYWLVWAVLFQAAVHVDSPRGFTSRFMTNVWALFAVVFLAIYTANLAAFMITREEF 767
               :||.....|.....|.|....: :|:.:::|.:...|..|.::.::.||||||||:....
  Fly   583 LENQFSFANCLWFSIGALLQQGSEL-APKAYSTRAVAASWWFFTLILVSSYTANLAAFLTVES-- 644

  Fly   768 HEFSGLNDSRLVHPFSHKPSF-----------KFGTIPYSHTDSTIHKYFNVMHNYMR---QYNK 818
                      ||.|.:.....           |.|...::....:.:..:..|:.:||   ||..
  Fly   645 ----------LVTPINDADDLSKNKGGVNYGAKIGGATFNFFKESNYPTYQRMYEFMRDNPQYMT 699

  Fly   819 TSVADGVAAVLNGNLDSFIYDGTVLDYLVAQDEDCRLMTVGSWYAMTGYGLAFSRNSKYVQMFNK 883
            .:..:||..|.|.|. :|:.:.|.::|:.  :..|.|..||:.....|||:|..:|..|....::
  Fly   700 NTNQEGVDRVENSNY-AFLMESTTIEYIT--ERRCTLTQVGALLDEKGYGIAMRKNWPYRDTLSQ 761

  Fly   884 RLLEFRANGDLERLRRYWMT-----GTCRPGKQEHKSSDPLALE--QFLSAFLLLMAGILLAALL 941
            .:||.:..|.|.:::..|..     |.|....::   |..:|||  .....||::..|......:
  Fly   762 AVLEMQEQGLLTKMKTKWWQEKRGGGACSDADED---SGAVALEISNLGGVFLVMGVGSFFGIFV 823

  Fly   942 LLLEHV 947
            .|||.|
  Fly   824 SLLEMV 829

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nmdar2	NP_001014714.1	PBP1_iGluR_NMDA_NR2	99..490	CDD:107373	91/435 (21%)
		PBP2_iGluR_NMDA_Nr2	502..908	CDD:270436	110/440 (25%)
		Lig_chan	665..928	CDD:278489	66/294 (22%)
Grik	NP_001262788.1	PBP1_iGluR_Kainate	37..391	CDD:107377	88/420 (21%)
		ANF_receptor	53..374	CDD:279440	77/377 (20%)
		Periplasmic_Binding_Protein_Type_2	411..781	CDD:304360	108/431 (25%)
		Lig_chan	543..816	CDD:278489	68/302 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45462855
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR18966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940