Protein Alignment Nmdar2 and Ir84a

DIOPT Version :10

• Sequence 1: NP_001014714.1
• Gene: Nmdar2 / 31107
• FlyBaseID: FBgn0053513
• Length: 1083
• Species: Drosophila melanogaster
• Sequence 2: NP_649720.2
• Gene: Ir84a / 40891
• FlyBaseID: FBgn0037501
• Length: 644
• Species: Drosophila melanogaster
• Alignment Length: 769
• Identity: 144/769 - (18%)
• Similarity: 261/769 - (33%)
• Gaps: 236/769 - (30%)

  Fly   261 QIAGHDDFVQAVRERVAEMQEHFKFTILNSIVVTRTSDL-----ME-----LVNSEARV------ 309
            ::|..:||:::         ||     |:.::|.|..|.     :|     |.|...:.
  Fly    34 ELAAFEDFLRS---------EH-----LSHVLVVRGDDADGDWKIECHQKLLANYRVQFYRPEMS 84

  Fly   310 -----MLLYATQTEAITILRA------------AEEMKLTGENYVWVVSQSVIEKKDAHSQFPVG 357
                 ::.|.:...|:.:|.:            |.|......:..|.:..|      .....||.
  Fly    85 ANFEDLMFYGSPRTAVLVLNSEHVLVRRQVFGVASEAGYFNNSLAWFILGS------GRESLPVE 143

  Fly   358 MLGVHFDTSSAALMNEISNAIKIYSYGVEAYLTDPANRDRRLTTQSLSCEDEGRGRWDNGEIFFK 422
            .|              |...:..|..|::|.:|...                 ||. ||..:.|.
  Fly   144 QL--------------IDQLLSGYRMGIDADITVAL-----------------RGP-DNASMLFY 176

  Fly   423 YLRNVSIEGDLNKPNIEFTADGDLRSAELKIMNLRPSANNKNLVWEEIGVW-------------K 474
            .:..:|                  |.|            |..|:.|:.|:|             .
  Fly   177 DVYRIS------------------RQA------------NTPLIIEKKGLWTHSGGYQKFGNFKN 211

  Fly   475 SWETQKLDIRDIAWPGNSHAPPQGVPEKFHLKITFLEEAPYINLSPADPVSGKCLMDRGVLCRVA 539
            :|..::.:..::...|:                |.|.|.|        |..|    |...|
  Fly   212 TWVIRRRNFLNVTLIGS----------------TVLTEKP--------PGFG----DMEYL---- 244

  Fly   540 ADHEMAADIDVGQAHRNESFYQCCSGFCIDLLEKFAEELGFTYELVRVEDGKWG-TLENGKWNGL 603
            ||.:....:|..|....:.|         .|:|:.     |...|......||| .|:||.|:|:
  Fly   245 ADDKQLQQLDPMQRKTYQLF---------QLVERM-----FNLSLAISLTDKWGELLDNGSWSGV 295

  Fly   604 IADLVNRKTDMVLTSLMINTEREAVVDFSEPFMETGIAIVV--AKRTGIISPTAFLEPFDTASWM 666
            :..:.:|:.|..:..:....:|:..|.:|.......|..:.  .:|:.|  ...|.||.....|.
  Fly   296 MGQVTSREADFAVCPIRFVLDRQPYVQYSAVLHTQNIHFLFRHPRRSHI--KNIFFEPLSNQVWW 358

  Fly   667 LVGIVAIQAATFMIFLFEWLSPSGYDMKLYLQNTNVTPYRFSLFRTYWLVWAVLFQAAVHVDSP- 730
            .|  :|:...:.::.||.        ::|....:|: ..|||      .||..:.:..:. ..|
  Fly   359 CV--LALVTGSTILLLFH--------VRLERMLSNM-ENRFS------FVWFTMLETYLQ-QGPA 405

  Fly   731 ----RGFTSRFMTNVWALFAVVFLAIYTANLAAFMITR--EEFHEFSGLNDSRLVHPFSHKPSFK 789
                |.|::|.:.::..:|:.:.:..|.|.:...:::.  ........|.||.|.....: .|:.
  Fly   406 NEIFRLFSTRLLISLSCIFSFMLMQFYGAFIVGSLLSESARSIVNLQALYDSNLAIGMEN-ISYN 469

  Fly   790 FGTIPYSHTDSTIHKYFNVMHNYMR------QYNKTSVADGVAAVLNGNLDSFIYDGTV------ 842
            |..  :::|.:.:     |...|::      ::|..|:..|...::.|.   |.:...:
  Fly   470 FPI--FTNTSNQL-----VRDVYVKKICKSGEHNIMSLQQGAERIIQGR---FAFHTAIDRMYRL 524

  Fly   843 -LDYLVAQDEDCRLMTVGSWYAMTGYGLAFSRNSKYVQMFNKRLLEFRANGDLERLRRYWMTGTC 906
             |:..:.:.|.|.|..| .:......|....:.|.:.:.....||.|||.|.|:...:.||..
  Fly   525 LLELQMDEAEFCDLQEV-MFNLPYDSGSVMPKGSPWREHLAHALLHFRATGLLQYNDKKWMVR-- 586

  Fly   907 RPGKQEHKSSD-PLALEQFLSAFLLLMAGILLAALLLLLEHVYFKYI---RKRL 956
            ||.....|:|. .:.||.|..|...|...::.:||:.||| ::..::   |:||
  Fly   587 RPDCSLFKTSQAEVDLEHFAPALFALALAMVASALVFLLE-LFLHWLPDFRRRL 639

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nmdar2	NP_001014714.1	PBP1_iGluR_NMDA_NR2	99..485	CDD:380601	41/269 (15%)
		PBP2_iGluR_NMDA_Nr2	502..908	CDD:270436	85/428 (20%)
Ir84a	NP_649720.2	ATP-sulfurylase	<54..>112	CDD:460310	8/57 (14%)
		Periplasmic_Binding_Protein_Type_2	<282..>355	CDD:473866	19/74 (26%)
		Lig_chan	353..602	CDD:459656	53/280 (19%)