Protein Alignment Nmdar2 and Ir75d

DIOPT Version :10

• Sequence 1: NP_001014714.1
• Gene: Nmdar2 / 31107
• FlyBaseID: FBgn0053513
• Length: 1083
• Species: Drosophila melanogaster
• Sequence 2: NP_649074.2
• Gene: Ir75d / 40065
• FlyBaseID: FBgn0036829
• Length: 675
• Species: Drosophila melanogaster
• Alignment Length: 646
• Identity: 126/646 - (19%)
• Similarity: 207/646 - (32%)
• Gaps: 223/646 - (34%)

  Fly   472 VWKSWETQKLD-----------IRDI----AWPGNSHAPPQGVPEKFHLKITFLEEAPYINLSPA 521
            :||.|:...|:           :||:    |...:..|||   |:.||...:...|..:  |.||
  Fly    76 LWKLWQHFNLNNFYVQVSTESSLRDLQHVDALDEHKDAPP---PKSFHANNSTHWETSF--LLPA 135

  Fly   522 DP---------VSGKCLMDRGVLCR--VAADH-------------EMAADID------------- 549
            .|         .|.:|.::   |.|  .|::|             |...|||
  Fly   136 LPYKMGILLLEFSSECALN---LLRWSAASEHNYFTTNRFWLLLTEDPGDIDLLEDPEIFIPPDS 197

  Fly   550 ---------------------------------VGQAHRNE--------------SFYQCCSGFC 567
                                             ||...||.              ::.|...|..
  Fly   198 ELRVLHYENVGNFSCSLIDLYKVAAWKPLKRTLVGHNIRNSRHVIHALQHFGSAITYRQDLEGIV 262

  Fly   568 -----------------------IDLLEK--------FAEELGFTYELVRVEDGKWGTLENGKWN 601
                                   ||.:.|        .|..|..:|...:..:..| ...||.::
  Fly   263 FNSAIVIAFPDLFTNIEDLSLRHIDTISKVNHRLMLELANRLNMSYNTYQTVNYGW-RQPNGSFD 326

  Fly   602 GLIADLVNRKTDMVLTSLMINTEREAVVDFSEPFMETGIAIVVAKRTGI------ISPTA--FLE 658
            ||:......:.|:...::.:..:|.|:|||        :|.....|.||      :|..|  |..
  Fly   327 GLMGRFQRYELDLAQLAIFMRLDRIALVDF--------VAETYRVRAGIMFRQPPLSAVANIFAM 383

  Fly   659 PFDTASWMLVGIVAIQAATFMIFLFE-WLSPSGYDMKLYLQNTNVTPYRFSLFRTYWLVWAVLFQ 722
            ||:...|  |.|:.:...|.::.:.| :.||..:||. |:...|             .||..:.|
  Fly   384 PFENDVW--VSILMLLIITTVVLVLELFFSPHNHDMS-YMDTLN-------------FVWGAMCQ 432

  Fly   723 AAVHVDSPRGFTSR---FMTNVWALFAVVFLAIYTANLAAFMIT-REEFHEFSGLNDSRL---VH 780
            ...:|: .|..::|   |.|.|.|||   ....::||:.|.:.: .:.....|.|..|.|   |.
  Fly   433 QGFYVE-VRNRSARIIVFTTFVAALF---LFTSFSANIVALLQSPSDAIQSLSDLGQSPLEIGVQ 493

  Fly   781 PFSHKPSFKFGTIPYSHTDSTIHKYFNVMHN---------YMRQYNKTSVADGVAAVLNGNLDSF 836
            ...:...:        .|:||.....|:.|.         |||...      |:..:..|   .|
  Fly   494 DTQYNKIY--------FTESTDPVTKNLYHKKIASKGENIYMRPLL------GMEKMRTG---LF 541

  Fly   837 IYDGTV-LDYLVAQD-----EDCRLMTVGSWYAMTGYGLAFSRNSKYVQMFNKRLLEFRANGDLE 895
            .|...: ..|.:..|     |.|.||.:.. :.:....:...:|..|.::..::|...|....:.
  Fly   542 AYQVELQAGYQIVSDTFSEPEKCGLMELEP-FQLPMLAIPTRKNFPYKELIRRQLRWQREVSLVN 605

  Fly   896 RLRRYWM--TGTCRPGKQEHKSSDPLALEQFLSAFLLLMAGILLAALLLLLEHVY--FKYI 952
            |..|.|:  ...|..|.....|   :.:.:...|..:...|..::.:|.|.|.::  ||.:
  Fly   606 REERKWIPQKPKCEGGVGGFVS---IGITECRYALGIFGCGAAVSFVLFLFEFIFRHFKQV 663

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nmdar2	NP_001014714.1	PBP1_iGluR_NMDA_NR2	99..485	CDD:380601	4/23 (17%)
		PBP2_iGluR_NMDA_Nr2	502..908	CDD:270436	106/553 (19%)
Ir75d	NP_649074.2	Periplasmic_Binding_Protein_Type_2	299..>372	CDD:473866	18/81 (22%)
		Lig_chan	386..643	CDD:459656	60/297 (20%)