Protein Alignment Nmdar2 and Ir75a

DIOPT Version :9

• Sequence 1: NP_001014714.1
• Gene: Nmdar2 / 31107
• FlyBaseID: FBgn0053513
• Length: 1083
• Species: Drosophila melanogaster
• Sequence 2: NP_649012.2
• Gene: Ir75a / 39982
• FlyBaseID: FBgn0036757
• Length: 629
• Species: Drosophila melanogaster
• Alignment Length: 657
• Identity: 126/657 - (19%)
• Similarity: 220/657 - (33%)
• Gaps: 204/657 - (31%)

  Fly   423 YLRNVSIEGDLNKPNIEFTADG----------DLR---SAELKIMNLRPSANNKNLVWEEIGVWK 474
            |.:.|.:.|.||..::|.:..|          |::   :.:|.....|....|::..|..:|
  Fly    50 YHQFVQMRGVLNWSHLELSYMGHTQPTLAIYVDIKCDQTQDLLEEASREQIYNQHYHWLLVG--- 111

  Fly   475 SWETQKLDIRDIAWPGNSHAPPQGVPEKFHL-KITFLEEAPYI-------NLSPADPV-----SG 526
              ...||:..|:                |.| .|:...:..|:       |.|.|..|     :|
  Fly   112 --NQSKLEFYDL----------------FGLFNISIDADVSYVKEQIQDNNDSVAYAVHDVYNNG 158

  Fly   527 KCLMDRGVLCRVAADHEMAADIDVGQAHRNESFYQCCSGF------------------------- 566
            |.:   |....|...|||:.|..|.:..|:.|..|..|.:
  Fly   159 KII---GGQLNVTGSHEMSCDPFVCRRTRHLSSLQKRSKYGNREQLTDVVLRVATVVTQRPLTLS 220

  Fly   567 --------------CIDLLEKFAEELGFTYELVRVED---GKWGTLENGKWN------GLIADLV 608
                          .||.|.:|    ||...|: :.|   .|...:.:..|:      |.:..:|
  Fly   221 DDELIRFLSQENDTHIDSLARF----GFHLTLI-LRDLLHCKMKFIFSDSWSKSDVVGGSVGAVV 280

  Fly   609 NRKTDMVLTSLMINTEREAVVDFSEPFMETG----IAIVVAKRTGIISPTAFLEPFDTASWMLVG 669
            ::..|:..|..:..   |..:.:....:|||    :.|........:....||:||....|.|.|
  Fly   281 DQTADLTATPSLAT---EGRLKYLSAIIETGFFRSVCIFRTPHNAGLRGDVFLQPFSPLVWYLFG 342

  Fly   670 IVAIQAATFMIFLFEWLSPSGYDMKLYLQNTNV-----TPYRFSLFRTYWLVWAVLFQAAVHVDS 729
                 ....:|.:..|::       .|::...:     ..|..||..|:    .:.|.||....|
  Fly   343 -----GVLSLIGVLLWIT-------FYMECKRMQKRWRLDYLPSLLSTF----LISFGAACIQSS 391

  Fly   730 ---PRGFTSRFMTNVWALFAVVFLA--IYTANLAAFMIT---REEFHEFSGLNDSRLVHPFSHKP 786
               ||....|.:  .:|||.:.|:.  .||:.:.:.:::   :.:......|.:|
  Fly   392 SLIPRSAGGRLI--YFALFLISFIMYNYYTSVVVSSLLSSPVKSKIKTMRQLAES---------- 444

  Fly   787 SFKFGTIPYSHTDSTIHKYFNV-----MHNYMRQYNKTSVAD---------GVAAVLNGNLDSFI 837
            |...|..|...|.|    |.|.     :|.::::..::...:         ||..|.:.....::
  Fly   445 SLTVGLEPLPFTKS----YLNYSRLPEIHLFIKRKIESQTQNPELWLPAEQGVLRVRDNPGYVYV 505

  Fly   838 YDGT-----VLDYLVAQDEDCRLMTV-----GSWYAMTGYGLAFSRNSKYVQMFNKRLLEFRANG 892
            ::.:     |..|..|| |.|.|..|     ..:|.      ...|||.|.::|..|.|.....|
  Fly   506 FETSSGYAYVERYFTAQ-EICDLNEVLFRPEQLFYT------HLHRNSTYKELFRLRFLRILETG 563

  Fly   893 DLERLRRYWMTGTCRPGKQEHKSSDPLA--------LEQFLSAFLLLMAGILLAALLLLLEHVYF 949
            ...:.|.||:          |.....:|        :|......|:|:...:|..::||:|..:.
  Fly   564 VYRKQRSYWV----------HMKLHCVAQNFVITVGMEYVAPLLLMLICADILVVVILLVELAWK 618

  Fly   950 KYIRKRL 956
            ::..:.|
  Fly   619 RFFTRHL 625

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nmdar2	NP_001014714.1	PBP1_iGluR_NMDA_NR2	99..490	CDD:107373	16/79 (20%)
		PBP2_iGluR_NMDA_Nr2	502..908	CDD:270436	100/507 (20%)
		Lig_chan	665..928	CDD:278489	59/307 (19%)
Ir75a	NP_649012.2	Lig_chan	337..603	CDD:306551	61/314 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45462783
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR18966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840